A5003579211- Obsessive-Compulsive Spectrum Disorders
- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Sexuality, Behavior, and Technology
- Suicide and Self-Harm Studies
- Body Image and Dysmorphia Studies
- Treatment of Major Depression
- Eating Disorders and Behaviors
- Sexual function and dysfunction studies
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Mental Health and Psychiatry
- Mental Health Treatment and Access
- Tryptophan and brain disorders
- Mental Health Research Topics
- Long-Term Effects of COVID-19
- Intensive Care Unit Cognitive Disorders
- Data-Driven Disease Surveillance
- Child and Adolescent Psychosocial and Emotional Development
- Psychology of Moral and Emotional Judgment
- Misinformation and Its Impacts
- Mental Health via Writing
- Stress Responses and Cortisol
- Hypothalamic control of reproductive hormones
- Digital Mental Health Interventions
- Psychosomatic Disorders and Their Treatments
University of Genoa
2009-2024
Ospedale Policlinico San Martino
2020-2024
Azienda Ospedaliera Universitaria Senese
2018
University of Miami
2012-2015
To present an updated, comprehensive review on clinical and pre-clinical studies agomelatine.A MEDLINE, Psycinfo Web of Science search (1966-May 2009) was performed using the following keywords: agomelatine, melatonin, S20098, efficacy, safety, adverse effect, pharmacokinetic, pharmacodynamic, major depressive disorder, bipolar Seasonal Affective Disorder (SAD), Alzheimer, ADHD, Generalized Anxiety (GAD), Panic (PD), Obsessive-Compulsive (OCD), anxiety disorders mood disorder. STUDY...
Previously institutionalized older patients with schizophrenia show changes in cognitive and functional capacity over time. This study examined real-world functioning a sample of people who varied their history long-term institutionalization related real world to cognition the follow-up period. Older (n=111) were assessments functioning, capacity, clinical symptoms, everyday functioning. They then followed up 45 months two times. Mixed-model regression was used examine social, living,...
OPINION article Front. Psychiatry, 03 August 2023Sec. Anxiety and Stress Disorders Volume 14 - 2023 | https://doi.org/10.3389/fpsyt.2023.1206304
As lithium treatment might be effective in reducing the risk of deliberate self-harm (DSH) adult patients with unipolar affective disorders, we designed a pragmatic randomised trial to assess its efficacy more than 200 treatment-resistant depression. However, 56 only. The aim this report is therefore twofold: first, disseminate results underpowered study which may incorporated into future meta-analytical reviews; second, analyse some critical aspects explain failure reach target sample size....
Social deficits are common in people with schizophrenia and the treatment of social skills has been a long-time strategy. However, negative (i.e., deficit) symptoms also appear to contribute dysfunction. In this study, we combined data from three separate studies (total n=561) who were assessed identical methods. We examined prediction real-world functioning, rated by high contact clinicians, comparing influence global specific ratings performance-based assessments on these outcomes....
Although recent data show that SARS-CoV-2 infection seems to affect the central nervous system (CNS), little is known about neuropsychiatric effects resulting from this condition. In addition well-known neurotrophism of coronaviruses, evidence shows also "cytokine storm" induced by at basis neuroinflammation CNS. Furthermore, prolonged hospitalization, polypharmacotherapy, and isolation could be onset delirium in hospitalized COVID patients. This multicentric observational study explores...
Long acting injectable (LAI) antipsychotics have been claimed to ensure treatment adherence and possibly reduce the daily burden of oral formulations. So far, only surveys investigating theoretical prescribing attitudes clinicians employed. On this basis, we aimed investigate reasons for LAIs in a real-world, unselected sample patients.The STAR Network Depot Study is an observational, multicentre study consecutively enrolling adults initiating LAI over 12-months period. Clinical severity was...
Data on therapeutic interventions following deliberate self harm (DSH) in patients with treatment-resistant depression (TRD) are very scant and there is no unanimous consensus the best pharmacological option for these patients. There some evidence that lithium treatment might be effective reducing risk of completed suicide adult unipolar affective disorders, however clear cut results have been found so far. The primary aim present study to assess whether adding standard therapy an strategy...
Abstract Instagram is the social network with largest number of adolescent users in Italy; it also suicide‐related posts. Suicide third leading cause death Italy 15–19 age group. This study aims to describe Italian posts on related suicide and investigate whether there are differences likes, comments, hashtags relation characteristics We searched for Italian‐language by typing ‘#suicidio’, an translation English word ‘suicide’, found 303 between January May 2022. Most were written ordinary...
Sexual response in obsessive-compulsive disorder (OCD) research and practice is overlooked. According to the Dual Control Model, satisfactory sexual based upon a balance of excitation inhibition. The assessment OCD may have clinical implications, such as integration sex therapy psychotherapeutic intervention. present study was aimed at comparing inhibition levels between patients matched control subjects, investigating whether obsessive beliefs might predict excitation/inhibition.Seventy-two...
Abstract Different findings would indicate that obsessive-compulsive disorder (OCD), a common psychiatric condition, might significantly impair intimate relationships and sexual well-being. The aim of the present study was to ascertain whether OCD outpatients with contamination/washing symptoms experience lower arousal than those experiencing other symptoms. In addition, we explored higher disgust propensity/sensitivity moderate relation between impaired arousal. A total 72 (27 45 symptoms)...
Abstract Background Highlighting the relationship between obsessive–compulsive disorder (OCD) and tic (TD), two highly disabling, comorbid, difficult-to-treat conditions, Diagnostic Statistical Manual of Mental Disorders, fifth edition (DSM-5) acknowledged a new “tic-related” specifier for OCD, ie, tic-related (OCTD). As patients with OCTD may frequently show poor treatment response, aim this multicenter study was to investigate rates clinical correlates remission, resistance in large sample...