A5056593471- Long-Term Effects of COVID-19
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
Institute of Life Sciences
2021
The response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is largely impacted by the level of virus exposure and status host immunity. nature protection shown direct asymptomatic contacts disease 2019 (COVID-19)-positive patients quite intriguing. In this study, we have characterized antibody titer, SARS-CoV-2 surrogate neutralization, cytokine levels, single-cell T-cell receptor (TCR), B-cell (BCR) profiling in contacts, infected cases, controls. We observed significant...
Abstract The response to SARS-CoV-2 is largely impacted by the level of exposure and status immunity. nature protection shown direct contacts COVID-19 positive patients quite intriguing note. We aimed study immune differences reinforcing contact individuals in circumventing disease. Our observation showed PCR developed elevated neutralizing antibody titres cytokine levels. On other hand, single cell data revealed differential usage V(D)J genes unique BCR clonotypes imparting protective...