The aim of our study is to compare the effects sugammadex and neostigmine, used for neuromuscular blockage antagonism, on postoperative nausea vomiting (PONV). Our was completed with 98 ASA I-II risk patients undergoing endotracheal intubation under general anesthesia. At end surgery were randomly divided into two groups given 2 mg kg−1 (Group S) or 50 μg neostigmine plus 0.2 atropine N). Monitoring recording times set as 1 hour from 1–6, 6–12, 12–24 hours. anti-emetic amounts administered...

BACKGROUND:Sugammadex is a reversal agent with well known advantages but it's effects on haemostasis and bleeding have been topic of interest. Septoplasty common surgical procedure postoperative respiratory complications bleeding. The aim this study to investigate the sugammadex coagulation parameters after septoplasty procedure. MATERIAL AND METHODS:In randomized controlled study, fifty patients were grouped into two groups; neostigmine (Group N) vs. S). For evaluation PT, aPTT INR, blood...

Schiff bases are compounds that have gained importance in the paint industry due to their colorful nature and field of chemistry biochemistry biological activities. Various applications bases, such as antitumor, antifungal, antibacterial, antioxidant, antituberculosis, anthelmintic, been widely studied. Within scope study, 5-bromo-2-hydroxybenzaldehyde amino acid methyl esters (isoleucine, phenylalanine, methionine) were synthesized first. The synthesis new Zn(II) complexes these was carried...

Objective:The aim of this study is to compare the sedative properties and haemodynamic respiratory effects dexmedetomidine a ketamine-propofol combination (ketofol), which are expected have minimal on spontaneous breathing.Methods: Sixty patients were enrolled in prospective randomised study.Patients divided into 2 groups according administration (Group D) ketofol K).Target sedation level was determined as Ramsay Sedation Score 3. In Group D, 0.5 mcg kg -1 administered via intravenous route...

The aim of this study was to measure the haemodynamic responses a etomidate-propofol combination used for anaesthesia induction and compare with separate use each drug.The patients were randomly divided into three groups as group P (n = 30, propofol 2.5 mg kg(-1)), E etomidate 0.3 kg(-1)) PE 1.25 kg(-1) + 0.15 kg(-1)). For patient, times measurement heart rate (HR) mean arterial pressure values defined baseline, after induction, before intubation, immediately intubation 1, 2, 3, 4, 5 10...

Tumor Necrosis Factor-α (TNF-α) and Interleukin-1β (IL-1β) are among the cytokines released secondary to surgical stress response. The objective of this study was investigate effect a Transversus Abdominis Plane (TAP) block on postoperative pain its immunomodulatory activity through proinflammatory cytokines.TAP (study group; n=40) or p-TAP (placebo n=40). Patients in TAP group underwent an Ultrasound (US) guided unilateral using 20-cc 0.5% bupivacaine solution. sham isotonic TNF-α IL-1β...

O objetivo de nosso estudo foi comparar os efeitos sugamadex e neostigmina, usados para o antagonismo do bloqueio neuromuscular em náusea vômito no pós‐operatório (NVPO). concluído com 98 pacientes risco ASA I‐II, submetidos à intubação traqueal sob anestesia geral. Ao final da cirurgia, foram aleatoriamente divididos dois grupos que receberam 2 mg kg−1 (Grupo A) ou 50 μg neostigmina mais 0,2 atropina N). Os tempos monitoração registro definidos como uma hora 1‐6, 6‐12 12‐24 horas. As...

Metal nanoparticles that are widely studied in optoelectronics, catalysis, medicine, and sensors offer remarkable optical electronic properties. To address the cost environmental concerns associated with their synthesis, this study employs an environmentally friendly method using Laureus nobilis extract to produce silver zinc nanoparticles, which prominent nanotechnology. This includes investigations of factors such as reaction time, AgNO3/laurel ratio, Zn(Ac)2·H2O/laurel ratio temperature...

To compare the postoperative analgesic efficacy and side effects of paracetamol tramadol in patients undergoing lumbar disc surgery.Group P (paracetamol group) was given 1 g intravenously 30 min before end operation each day at 6-h intervals. Group T (tramadol 1.5 mg/kg as a loading dose patient-controlled analgesia for day. Hemodynamic parameters, modified Aldrete score, Ramsay sedation scale patient satisfaction (PSS) visual analog (VAS) nausea/vomiting additional needs/times were...

In this study, we prepared nine Schiff bases by condensation of amino acid methyl esters (isoleucine, phenylalanine and methionine) with salicylaldehyde derivatives (2,4-dihydroxybenzaldehyde, 2-hydroxy-3-methoxybenzaldehyde 5-bromo-2-hydroxybenzaldehyde) characterized various spectroscopic methods (FT-IR, UV-Vis NMR techniques). FT-IR spectra exhibited characteristic peaks for all imine compounds. pointed out the bond which is indicator formation bases. Besides, antiproliferative cytotoxic...

Objective:The aim of this study is to compare general anaesthesia (GA) versus regional (RA) for endovascular aneurysm repair (EVAR). Methods:We analysed the files 89 patients between August 2010-August 2012 who underwent elective EVAR retrospectively. Results:We performed RA 32 (36%) and GA 57 (64%).The operations were completed successfully in both groups did not require conventional surgery.The mean age was 71.5±7 (range 50-88 years).RA preferred more than presence advanced-stage chronic...

Cerebral ischemia-reperfusion (I/R) injury causes neurological dysfunction and cell death. Sugammadex, as a large molecule, is normally difficult to pass through the blood-brain barrier (BBB). In ischemia, molecules can into brain tissue. this study, we aimed evaluate effect of sugammadex in presence cerebral I/R damage rats with general anesthesia model sevoflurane rocuronium.

Objective: Sleep is one of the basic daily activities that are important for an individual with physical, mental, social, and intellectual needs to be in good physical mental health. Although many definitions made, sleep; a complex physiological event affected by pathophysiological, psychological, environmental factors. Anesthesiologists often work closed environments long working hours, which can cause severe, chronic sleep loss disruption. Sleeplessness low quality decreased attention...

ÖzPurpose: We aimed to evaluate frequency of electroconvulsive therapy (ECT) use among hospitalized patients in a psychiatry clinic university hospital and determine the diagnostic, socioodemographic features these ECT treated retrospectively.Material Method: Of 759 inpatients, 32 who was with Ministery Health-Ordu University Training Research Hospital were included study.The data evaluated study obtained from patient files retrospectively.Results: Among (4.21%) ECT, 23 (71.9%) male mean age...

Acute acetaminophen (APAP) overdose has been shown to cause toxicity and the primary treatment medication is N-acetylcysteine (NAC). Dexmedetomidine (DEX) a sedative drug with known antioxidant properties. We researched whether DEX an injury-reducing effect on toxicity.Rats were divided into: Group I (control), II III (NAC) IV V (NAC+DEX). Histopathologic investigations of tissues performed glutathione peroxidase (GSH-Px), catalase (CAT), malondialdehyde (MDA), myeloperoxidase (MPO) beta...

Endovascular aneurysm repair (EVAR) is increasingly being used in abdominal aortic (AAA) treatment, as it less invasive than open surgery. A wide range of anaesthetic types, such general anaesthesia, neuroaxial blocks and local have been shown to be appropriate for the EVAR procedure. In continuous spinal anaesthesia (CSA) method, may titrated through a catheter placed subarachnoid space, allowing better control level reduction potential haemodynamic side effects. Our aim present CSA...

ABSTRACT Objective: The aim of this prospective randomized trial is to verify whether there an association between the methods administration enteral nutrition and leptin ghrelin hormones, which have a major role in regulation energy metabolism. Methods: This study enrolled 38 enteral-fed patients aged 18 85 Intensive Care Unit. were prospectively receive either continuous infusion (n=19) or intermittent feeding (n=18) nutrition. In addition routine biochemical assays, blood samples taken...

The aim of the study was to compare block characteristics and clinical effects dextrose added levobupivacaine solutions at different concentrations provide unilateral spinal anaesthesia in lower extremity surgery.This prospective, randomised, double-blind comprised 75 ASA I-II risk patients for whom total knee arthroscopy planned. were assigned three groups: Group I, 60mg 7.5mg 0.5% levobupivacaine, II, 80mg III, 100mg. Spinal applied patient lateral decubitus position with operated side...

Elektrokonvulsif tedavi (EKT), pek çok psikiyatrik bozuklukta etkili olan bir biçimidir.Anestezi uygulaması, hem EKT'nin başarılı olmasında rol oynar de işlem sırasında vücudun oksijen kullanımını iyileştirir

A very efficient ligand-free method was developed for the transfer hydrogenation of ketones and aldehydes catalyzed by different metal complexes. With this catalytic system, performance stability Ir, Ru, Pd complexes were more favorable than those previously reported systems hydrogenation. This system showed good excellent activity even with lower catalyst concentrations tested.

Abstract Objective: Determination of the factors associated with intensive care unit (ICU) prognosis and mortality has important role in clinical follow-up patients. Definition novel biomarkers, beside older biomarkers available for evaluation outcome these patients been proposed. Platelet-activating factor acetylhydrolase (PAF-AH) is an enzyme that inactivates platelet-activating factor. A reduction level PAF-AH demonstrated during systemic inflammation multiple organ failure. This research...