A5061503957- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Retinal and Optic Conditions
- Polyomavirus and related diseases
- Systemic Lupus Erythematosus Research
- Ocular Diseases and Behçet’s Syndrome
- Cerebral Venous Sinus Thrombosis
- Rheumatoid Arthritis Research and Therapies
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Mosquito-borne diseases and control
- Systemic Sclerosis and Related Diseases
- Neurosurgical Procedures and Complications
- interferon and immune responses
- Ophthalmology and Eye Disorders
- Health Systems, Economic Evaluations, Quality of Life
- Psoriasis: Treatment and Pathogenesis
- Glaucoma and retinal disorders
- Glioma Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Viral Infections and Vectors
- Autoimmune Neurological Disorders and Treatments
- Intracerebral and Subarachnoid Hemorrhage Research
- Hereditary Neurological Disorders
- Viral Infections and Immunology Research
- Chemokine receptors and signaling
University of Calgary
2015-2025
Alberta Health Services
2014-2024
Health Sciences Centre
2017-2024
Deleted Institution
2021-2023
National Institute of Neurological Disorders and Stroke
2023
Ontario Brain Institute
2015-2022
Allen Institute for Brain Science
2020-2021
Centre National pour la Recherche Scientifique et Technique (CNRST)
2021
Montreal Neurological Institute and Hospital
2019
Alberta Bible College
2014-2019
Background: There is a role for brief assessment instruments in detection and management of major depression MS. However, candidate scales have rarely been validated against diagnostic interview. In this study, we evaluated the performance several scales: Patient Health Questionnaire (PHQ)-9, PHQ-2, Center Epidemiologic Studies Depression rating scale (CES-D), Hospital Anxiety Scale (HADS-D) relation to Structured Clinical Interview DSM-IV (SCID). Methods: The sample was an unselected series...
In this prospective case series, we aimed to characterise the temporal evolution of functional and structural measures in afferent visual pathway patients with acute optic neuritis (ON).Fifty ON were followed over 12 months. Testing spectral-domain optical coherence tomography, Early Treatment Diabetic Retinopathy Study logarithm minimum angle resolution (LogMAR) acuity Humphrey perimetry central 30-2 threshold (SITA strategy) was performed at baseline, 3, 6 months after symptom onset. The...
Abstract Background: Over the past four years, West Nile virus (WNV) has become a significant health issue in North America. In 2002, WNV infection made its first appearance human population Canada. Methods: Patients who presented to University Health Network and Mount Sinai Hospital Toronto with neurological disease attributed were identified followed by neurology service. Clinical features results of laboratory, electrodiagnostic, radiological pathological studies are presented. Results:...
<h3>Objective:</h3> The primary objective of this study was to explore the potential influence gender on recovery from optic neuritis (ON) by determining whether differences in retinal nerve fiber layer (RNFL) thickness can be detected between men and women 6 months after an ON event. <h3>Methods:</h3> In prospective cohort study, 39 105 with acute underwent repeat visual optical coherence tomography (OCT) testing. main outcome measures were change RNFL measurements for male female patients...
ABSTRACT: Background: The “chronic cerebrospinal venous insufficiency” or “CCSVI” hypothesis, namely that multiple sclerosis (MS) is caused by abnormalities in the azygous and internal jugular veins with subsequent alterations hemodynamics central nervous system, has been a dominant topic MS care Canada over past year. Although there no methodologically rigorous evidence to support this hypothesis presently, considerable number of patients have undergone endovascular CCSVI procedures. Such...
Disease modifying therapies (DMTs) reduce the frequency of relapses and accumulation disability in multiple sclerosis (MS). Long-term persistence with treatment is important to optimize benefit. This long-term, cohort study was conducted at Calgary MS Clinic. All consenting adults relapsing-remitting who started either glatiramer acetate (GA) or interferon-β 1a/1b (IFN-β) between January 1st, 1996 July 2011 were included. Follow-up continued February 2014. Time-to-discontinuation initial...
Background: Risk factors for aquaporin-4 (AQP4+) antibody neuromyelitis optica spectrum disorder (NMOSD) are not well-established. Objective: To investigate demographic and environmental associated with NMOSD using a validated questionnaire case–control design. Methods: We enrolled patients AQP4 + through six Canadian Multiple Sclerosis Clinics. Participants completed the Environmental Factors in Study (EnvIMS) questionnaire. Their responses were compared to those of 956 unaffected controls...