- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Aortic Disease and Treatment Approaches
- Mechanical Circulatory Support Devices
- Antimicrobial Resistance in Staphylococcus
- Aortic aneurysm repair treatments
- Acute Myocardial Infarction Research
- Streptococcal Infections and Treatments
- Cardiac Arrest and Resuscitation
- Venous Thromboembolism Diagnosis and Management
- Heart Failure Treatment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac electrophysiology and arrhythmias
- Cardiac pacing and defibrillation studies
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Pulmonary Hypertension Research and Treatments
- Pericarditis and Cardiac Tamponade
- Atrial Fibrillation Management and Outcomes
- Spanish Literature and Culture Studies
- Historical Studies in Latin America
- Acute Ischemic Stroke Management
- Intensive Care Unit Cognitive Disorders
- Cardiac tumors and thrombi
Hospital Clínico San Carlos
2015-2024
Instituto de Investigación Sanitaria del Hospital Clínico San Carlos
2014-2022
Institute of Clinical and Experimental Medicine
2021
Freeman Hospital
2019-2020
Universidad Autónoma de Madrid
2018
Creative Commons
2014
Hospital Universitario de La Princesa
2014
Christie's
2014
Cardiovascular Institute Hospital
2013
The prognosis of patients with infective endocarditis (IE) remains poor despite the great advances in last decades. One factors closely related to mortality is development septic shock (SS). aim our study was describe profile IE complicated SS, and identify prognostic new-onset SS during hospitalization. We conducted a prospective including 894 episodes diagnosed at three tertiary centres. A backward logistic regression analysis undertaken determine associated development. Multivariable...
<h3>Objective</h3> To develop and validate a calculator to predict the risk of in-hospital mortality in patients with active infective endocarditis (IE) undergoing cardiac surgery. <h3>Methods</h3> Thousand two hundred ninety-nine consecutive IE were prospectively recruited (1996–2014) retrospectively analysed. Left-sided who underwent surgery (n=671) form our study population randomised into development (n=424) validation (n=247) samples. Variables statistically significant in-mortality...
Persistent infection is not a scientific evidence-based definition. The guidelines of infective endocarditis (IE) establish cut-off point 7-10 days, which arbitrary and probably too long. Our hypothesis that persistent positive blood cultures after 48-72 h from the initiation antibiotic therapy are associated with worse prognosis in patients left-sided IE.We repeated treatment 407 IE total 692 episodes consecutively diagnosed 1996 to 2011. We have compared profile whose became negative those...
From an epidemiologic point of view, right-sided infective endocarditis (RSIE) affects different types patients: intravenous drug users (IDUs), cardiac device carriers (pacemakers and implantable automatic defibrillators), the "3 noes" group: no left-sided, IDUs, devices. Our objective is to describe compare clinical profile outcome these groups patients. Every episode (IE) consecutively diagnosed in 3 tertiary centers from 1996 2012 was included ongoing multipurpose database. We assessed 85...
Background: Recent advances in the diagnosis and treatment of acute aortic syndrome should improve outcome this disease. The Spanish Registry Acute Aortic Syndrome aimed to assess current results management a wide cohort hospitals same geographical area. Methods: From January 2012 2014, 26 tertiary included 629 consecutive patients with syndrome: 73% men, mean age 64.7±14 years (range 22–92), 443 type A (70.4%) 186 B (29.6%). Results: Time elapsed between symptom onset was <12 hours 70.7%...
Abstract Funding Acknowledgements None. Background Most acute pulmonary embolism (PE) patients receive anticoagulation as a sole treatment. Reperfusion therapies are required in high-risk (HR) and intermediate-risk (IR)-PE with clinical deterioration. Systemic thrombolysis (ST) is the first-line reperfusion therapy, but due to contraindications major bleeding concerns, catheter-directed (CDT) rising suitable alternative. Purpose The main objective of this study was look for predictors that...
Acute onset of infective endocarditis has been previously linked to the development septic shock and a worse prognosis. The purpose this study was analyse clinical features in-hospital evolution patients with acute-onset as well potential role early surgery in treatment these patients.From 1996 2014, 1053 consecutive left-sided were prospectively included. Patients classified into 2 groups according presentation: (n = 491) non-acute 562). Acute-onset considered when time between appearance...
Objectives To evaluate the safety and midterm hemodynamic results of direct transcatheter aortic valve replacement (TAVR) without pre‐implantation balloon valvuloplasty (BAV). Background BAV was considered a mandatory previous step in TAVR procedures. Methods A total 339 consecutive patients who underwent transfemoral were prospectively selected. 1:1 matching conducted, pairing age, prosthesis type (self‐expandable or expandable) size, calcification grade (48% with moderate to severe...
The incidence of aortitis in patients with thoracic aortic diseases is not well established. aim this study was to analyse the frequency and clinical course a surgical series.320 consecutive ascending aorta/aortic arch aneurysm or acute syndrome who underwent surgery from 2012 2017 single tertiary referral hospital were retrospectively reviewed. Epidemiological data, variables related diagnosis, treatment follow-up collected histologically proven aortitis.From 320 examined samples, 279...