A5101637195- MicroRNA in disease regulation
- Extracellular vesicles in disease
- Mesenchymal stem cell research
- Plant Molecular Biology Research
- Histone Deacetylase Inhibitors Research
- Periodontal Regeneration and Treatments
- Circular RNAs in diseases
- Epigenetics and DNA Methylation
- Plant Reproductive Biology
- Cancer, Hypoxia, and Metabolism
- Protein Degradation and Inhibitors
- Magnolia and Illicium research
- Food Chemistry and Fat Analysis
- Meat and Animal Product Quality
- Oral microbiology and periodontitis research
- Obstructive Sleep Apnea Research
- Botanical Research and Applications
- Plant Parasitism and Resistance
- Plant-derived Lignans Synthesis and Bioactivity
- Bone Tissue Engineering Materials
- Polysaccharides and Plant Cell Walls
- Plant Diversity and Evolution
- Biocrusts and Microbial Ecology
- Cancer-related molecular mechanisms research
- Plant Gene Expression Analysis
Nanjing Forestry University
2019-2024
Chinese PLA General Hospital
2015-2024
Tianjin Huanhu Hospital
2022
Nankai University
2022
Zero to Three
2022
Tianjin University of Science and Technology
2021
Nanjing Medical University
2019-2020
Academy of Military Medical Sciences
2015
Periodontal bone defects occur in a wide variety of clinical situations. Adult stem cell- and biomaterial-based tissue regeneration are promising alternative to natural grafts. Recent evidence has demonstrated that two populations adult marrow mesenchymal stromal cells (BMSCs) can be distinguished based on their embryonic origins. These BMSCs not interchangeable, as bones preferentially heal using share the same origin. However, feasibility engineering human craniofacial was unclear. The...
Circulating microRNAs (miRNAs) prove to be potential non-invasive indicators of cancers. The purpose this study is profile serum miRNA expression in breast cancer (BC) patients find biomarkers for BC diagnosis.The patterns samples from 216 and 214 normal control subjects were compared. A four-phase validation was conducted biomarker identification. In the screening phase, Exiqon qPCR panel employed select candidates, which further analyzed by quantitative reverse transcriptase PCR following...
To determine the utility of plasma microRNAs (miRNAs) as biomarkers in cervical cancer (CC).Some studies were conducted about specific expression miRNAs diagnosis CC. Plasma samples 97 CC patients and 87 normal controls (NCs) used to identify dysregulation training, testing, external validation phases. Receiver operating characteristic (ROC) curves area under ROC curve (AUC) evaluate sensitivity specificity identified individual miRNA panels for Expression levels also examined exosomes...
Bone is a self-renewing tissue. marrow mesenchymal stromal cells (BMSCs) are located in the adult skeleton and believed to be involved maintenance of skeletal homeostasis throughout life. With increasing age, ability repair itself decreases, possibly due reduced functional capacity BMSCs. Recent evidence has suggested existence at least two populations BMSCs with different embryonic origins that cannot interchanged during stem cell recruitment: craniofacial (neural crest origin) appendicular...
Magnolia × soulangeana 'Changchun' are trees that bloom in spring and summer respectively after flower bud differentiation. Here, we use phenological morphological observation RNA-seq technology to study the molecular basis of flowering initiation 'Changchun'. During process summer, growth expanded buds increased significantly, their shape was obviously enlarged, which indicated initiated. A total 168,120 expressed genes were identified dormant buds, 11,687 showed significantly differential...
Abstract Oral squamous cell carcinoma (OSCC) is the prime kind of human malignancy with a great mortality ratio and deprived prognosis due to its high level relapse metastasis. Recently reported that betanin exerts preventive role cytotoxic activity on numerous cancer cells. Betanin comprises betalain group, which highly bioavailable antioxidant. However, precise molecular actions in OSCC cells are yet be elucidated. It may first report antiproliferative apoptotic mechanisms OSCC. The...
Background: Oral appliance (OA) treatment for obstructive sleep apnea syndrome (OSAS) has attracted more and attention due to its low price, comfort, portable non-invasion. This study aimed investigate the clinical effectiveness of adjustable oral on older adult patients with OSAS. Methods: Thirty diagnosed OSAS were chosen as participants received an OA 6 months. Then, subjected a polysomnographic examination, Berlin Questionnaire (BQ) scale questionnaire, cone beam computer tomography...
In angiosperms, floral architecture diversity reflects its significance in exploring plant evolution. Magnolia polytepala, an endemic and ancient species China, possesses a unique multi-tepal trait. Notably, the origin formation of these multi-tepals are poorly understood. this study, we investigated from inner whorl elucidated underlying molecular regulatory mechanisms by combining phenotypic analysis, sequencing, experiments. We found that exhibited morpho-anatomical characteristics...
Objective: Asiaticoside (AS), an active compound extracted from Centella asiatica, can promote the osteogenic differentiation of human periodontal ligament cells. In this study, we investigated impact AS on lipopolysaccharide (LPS)-induced osteoblast and inflammatory response in stem cells (hPDLSCs) its possible mechanisms. Method: hPDLSCs were treated with LPS to establish a model mimicking periodontitis then administered different concentrations (30, 60, 120 μM). Flow cytometry CCK-8...
Background: Medullary infarction (MI) often leads to severe dysphagia and sudden death. We investigated whether was associated with Methods: Patients MI were divided into death group nonsudden group. Dysphagia evaluated in 2 ways: the water-swallowing test (WST) points degree of dysphagia. Random undersampling (RUS), random oversampling (ROS), synthetic minority technique (SMOTE) techniques used process original data solve imbalance problem between classes. Univariate multivariate logistic...