A5026705101- Photodynamic Therapy Research Studies
- Reproductive Biology and Fertility
- Sperm and Testicular Function
- Nanoplatforms for cancer theranostics
- Endometriosis Research and Treatment
- Orbital Angular Momentum in Optics
- Reproductive Health and Technologies
- Ovarian function and disorders
- Photoacoustic and Ultrasonic Imaging
- Assisted Reproductive Technology and Twin Pregnancy
- Microfluidic and Bio-sensing Technologies
- Gynecological conditions and treatments
- Skin Protection and Aging
- Porphyrin and Phthalocyanine Chemistry
- Optical Imaging and Spectroscopy Techniques
- Solid State Laser Technologies
- Dermatologic Treatments and Research
- Reproductive System and Pregnancy
- Ultrasound and Hyperthermia Applications
- Uterine Myomas and Treatments
- Minimally Invasive Surgical Techniques
- Pelvic floor disorders treatments
- Pleural and Pulmonary Diseases
- Genital Health and Disease
- Spectroscopy Techniques in Biomedical and Chemical Research
Beckman Laser Institute and Medical Clinic
2004-2024
University of California, Irvine
2000-2024
Tel Aviv University
1990-2013
Rabin Medical Center
1991-2013
Karolinska University Hospital
2011
Mitera Hospital
2011
Reinier de Graaf Hospital
2011
Amsterdam UMC Location University of Amsterdam
2011
Bar-Ilan University
1992-2009
Sheba Medical Center
2009
Optical traps offer the promise of being used as noninvasive micromanipulators for biological objects. An analytical model was developed that accurately describes forces exerted on dielectric microspheres while in a single-beam gradient force optical trap. The can be extended to trapping predicts existence stable point and effective range. A minimum power approximately 5 mW an range 2.4 mu m were measured 10- m-diameter are reasonable agreement with expected results. In cell biology, trap...
The aims of this study were: (i) to quantify near-infrared optical properties normal cervical tissues and high-grade squamous intra-epithelial lesions (H-SIL); (ii) assess the feasibility differentiating from H-SIL on basis these properties; (iii) determine how tissue change following photodynamic therapy (PDT) in vivo. Using frequency domain photon migration technique, non-invasive measurements dysplastic ecto-cervical properties, i.e. absorption (μa) effective scattering coefficients,...
Photodynamic therapy (PDT) based on topical application of photosensitizers has been under development over the last years. Typical applications are treatment basal cell carcinoma skin and photoablation endometrium. The dosimetry for topically administered must take a time-dependent inhomogenous drug distribution into account together with conventional parameters such as optical scattering, absorption, photobleaching.This study presents model where cytotoxic dose is calculated in stepwise...
Photostress has to be considered during optical micromanipulation of gametes. Ultraviolet light, including low-energy UVA (32-400 nm) radiation, as well high-intensity near infrared (NIR) laser radiation may induce cell damage. A total number 580 light-exposed sperm cells were studied in single-cell photostress experiments. Low-power (1.5 mW, 5.3 W/cm2) exposure with 365 nm a standard mercury microscopy lamp human spermatozoa resulted within 109 +/- 30 s paralysis and 310 110 death....
Abstract Background and Objectives To determine the safety efficacy of 5‐aminolevulinic acid (ALA) as a topically applied photosensitizer for photodynamic therapy (PDT) cervical intraepithelial neoplasia (CIN). Study Designs/Materials Methods Forty women, who were at least 18 years old with persistent biopsy‐proven CIN 2 3 within previous months enrollment, underwent PDT in phase I II design. Five escalating radiant energies (increments 25 J/cm , beginning 50–150 ) using Coherent Dye Model...
Benzoporphyrin-derivative (BPD)–monoacid-ring A photodynamic therapy (PDT) was performed on subcutaneous tumor implants in a rat ovarian cancer model. In order to assess PDT efficacy the and normal tissue optical properties were measured noninvasively prior during using frequency-domain photon migration (FDPM). FDPM data used quantify absorption reduced scattering (given by parameters μa μ′s, respectively) at four near-infrared (NIR) wavelengths (674, 811, 849 956 nm). Tissue physiologic...