A5065527674- Sulfur Compounds in Biology
- Glaucoma and retinal disorders
- Neuroscience and Neuropharmacology Research
- Biochemical effects in animals
- Amino Acid Enzymes and Metabolism
- Neuroscience of respiration and sleep
- Retinal Development and Disorders
- Nitric Oxide and Endothelin Effects
- Nicotinic Acetylcholine Receptors Study
- Connexins and lens biology
- Antioxidant Activity and Oxidative Stress
- Eicosanoids and Hypertension Pharmacology
- Receptor Mechanisms and Signaling
- Retinoids in leukemia and cellular processes
- Mast cells and histamine
- Redox biology and oxidative stress
- Biomedical Research and Pathophysiology
- Molecular Sensors and Ion Detection
- Neurotransmitter Receptor Influence on Behavior
- Cannabis and Cannabinoid Research
- Obstructive Sleep Apnea Research
- Ion Transport and Channel Regulation
- Ocular Surface and Contact Lens
- Photoreceptor and optogenetics research
- Retinal Diseases and Treatments
Creighton University
2016-2025
Texas Southern University
2020
CHI Health Creighton University Medical Center - Bergan Mercy
2004-2013
University Medical Center
2007
University of Houston
2004
Alcon (United States)
2003
Both hydrogen sulfide and endocannabinoids can protect the neural retina from toxic insults under in vitro vivo conditions. Purpose: The aim of present study was two-fold: (a) to examine neuroprotective action cannabinoids [methanandamide 2-arachidonyl glycerol (2-AG)] against peroxide (H2O2)-induced oxidative damage isolated bovine (b) evaluate role endogenously biosynthesized (H2S) inhibitory actions on stress retina. Methods: Isolated retinas cows were exposed using H2O2 (100 µM) for 10...
In this study, we investigated the effect of a slow-releasing hydrogen sulfide (H2S) donor, GYY 4137, on intraocular pressure (IOP) in normotensive rabbits. Furthermore, compared IOP-lowering action 4137 with those elicited by other H2S-producing compounds, l-cysteine and ACS67 (a hybrid compound latanoprost an H2S-releasing moiety).IOP was measured New Zealand male albino rabbits using pneumatonometer (model 30 classic; Reichert Ophthalmic Instruments, Depew, NY). At 0 h, 50 μL test...
Abstract Hydrogen sulfide (H 2 S) is a multifaceted gasotransmitter molecule which has potential applications in many pathological conditions including lowering intraocular pressure and providing retinal neuroprotection. However, its unique physicochemical properties pose several challenges for developing efficient safe delivery method system. This study aims to overcome related H S toxicity, gaseous nature, narrow therapeutic concentrations range by polymeric microparticles sustain the...
We have evidence that hydrogen sulfide (H