A5100447758- Thyroid Disorders and Treatments
- Trace Elements in Health
- Redox biology and oxidative stress
- Birth, Development, and Health
- Growth Hormone and Insulin-like Growth Factors
- Chemical Synthesis and Analysis
- Genomics, phytochemicals, and oxidative stress
- Image Retrieval and Classification Techniques
- Glutathione Transferases and Polymorphisms
- Supramolecular Self-Assembly in Materials
- Anesthesia and Neurotoxicity Research
- Chemical Analysis and Environmental Impact
- ATP Synthase and ATPases Research
- AI in cancer detection
- Mitochondrial Function and Pathology
- Asymmetric Synthesis and Catalysis
- Advanced Image Fusion Techniques
Tianjin Medical University
2014-2018
Anyang Normal University
2016
A major source of reactive oxygen species (ROS) generation is the mitochondria. By using flow cytometry mitochondrial fluorescent probe, MitoSOX Red, western blot ROS scavenger Peroxiredoxin (Prx) 3 and fluorescence immunostaining, ELISA cleaved caspases 9, TUNEL staining, we demonstrated that exposure to 100 μ M KI for 2 hours significantly increased superoxide production Prx protein expression with expressions 9. Besides, indicated dismutase (SOD) at 1000 unit/mL attenuated increase in...
Wistar rats were randomly divided into groups of varying iodide intake: normal iodide; 10 times high and 100 on Days 7, 14, 28. Insignificant changes observed in thyroid hormone levels ( p > 0.05). Urinary iodine concentration content the glands increased after consumption from NI to HI < The urinary group 28 was 60–80 that group. mitochondrial superoxide production expressions Nrf2, Srx, Prx 3 all significantly increased, while Keap 1 decreased when compared or Immunofluorescence...
We aim to figure out the effect of metallothioneins on iodide excess induced oxidative stress in thyroid. Eight-week-old MT-I/II knockout (MT-I/II KO) mice and background-matched wild-type (WT) were used. Mitochondrial superoxide production peroxiredoxin (Prx) 3 expression measured. In vitro study, more significant increases mitochondrial Prx detected KO groups. vivo significantly higher concentrations urinary iodine level 100 HI group. Compared NI group, there was no difference existing...
Increased oxidative stress has been suggested as one of the underlying mechanisms in iodide excess-induced thyroid disease. Metallothioneins (MTs) are regarded scavengers reactive oxygen species (ROS) stress. Our aim is to investigate effects propylthiouracil (PTU), a peroxidase inhibitor, perchlorate (KClO₄), competitive inhibitor transport, and stimulating hormone (TSH) on mitochondrial superoxide production instigated by high concentrations thyroids MT-I/II knockout (MT-I/II KO) mice....
In order to improve accuracy of computer-aided diagnosis breast lumps, the authors introduce an improved interactive segmentation method based on Live Wire. This paper presents Gabor filters and FCM clustering algorithm is introduced Wire cost function definition. According image analysis for edge enhancement, we eliminate interference weak access external features clear results lumps through improving two cases data. Compared with traditional segmentation, experimental show that achieves...
Abstract An operationally simple method for the oxidative coupling of cyclohexene to a variety N‐heterocycles is demonstrated.