A5017525703- Eosinophilic Esophagitis
- Liver Disease Diagnosis and Treatment
- Cardiac, Anesthesia and Surgical Outcomes
- Esophageal Cancer Research and Treatment
- Diabetes Treatment and Management
- Microscopic Colitis
- Genetic factors in colorectal cancer
- Metastasis and carcinoma case studies
- Chronic Kidney Disease and Diabetes
- Gastroesophageal reflux and treatments
- Cancer Cells and Metastasis
- Helicobacter pylori-related gastroenterology studies
- Cancer, Hypoxia, and Metabolism
- Ultrasound Imaging and Elastography
- HIV-related health complications and treatments
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Constructed Wetlands for Wastewater Treatment
- DNA and Biological Computing
- Pleural and Pulmonary Diseases
- Biological Research and Disease Studies
- Medical Imaging and Pathology Studies
- Infrared Thermography in Medicine
- Wnt/β-catenin signaling in development and cancer
- Frailty in Older Adults
- Cardiovascular Health and Risk Factors
Mansoura University
2015-2025
University of Gezira
2025
Yale New Haven Hospital
2023
Istanbul University
2023
University of Kirkuk
2021
Karary University
2020
Orange Regional Medical Center
2019-2020
Cornell University
2018-2019
Weill Cornell Medicine
2018-2019
Brown University
2018-2019
Programmed Death-Ligand 1 (PD-L1) and Cytotoxic T Lymphocyte -Associated Antigen-4 (CTLA-4) are presently considered as prognostic markers therapeutic targets in numerous human malignancies. The goal of this study was to determine whether PD-L1 CTLA-4 might be used predict patients' survival Triple Negative Breast Cancer (TNBC). This retrospective cohort analyzed 100 primary TNBC cases that had surgical resection at the Oncology Center Mansoura University (OCMU), Faculty Medicine, Egypt....
Abstract Background Breast cancer is a significant global health issue and leading cause of female deaths worldwide. Ultrasonography (US) an adjunct technique for early diagnosis breast but has low specificity. So, researchers have suggested using US elastography to distinguish between benign malignant lesions, which may lead decrease in unnecessary biopsy rates. We aimed assess the diagnostic performance strain if there was increase accuracy after adding it conventional results BI-RADS 4...
Abstract Background Epithelial–mesenchymal transition (EMT) is a key step in the development of colorectal cancer (CRC) that confers metastatic capabilities to cells. The present study aimed assess immunohistochemical (IHC) expression and impact EMT markers, including E-cadherin, Vimentin, β-catenin, SMAD4, on oncologic outcomes CRC. Methods This was retrospective review 118 CRC patients. Tissue slides were retrieved from slide archive five tissue microarray construction blocks constructed....
Renal hypoxia is one of the currently highlighted pathophysiologic mechanisms diabetic nephropathy (DN). Both hypoxia-inducible factor-1α (HIF-1α) and HIF-2α are major regulators renal adaptive responses to hypoxia.This study aims compare effects vildagliptin (a dipeptidyl peptidase-IV inhibitor, DPP-4i) empagliflozin sodium-glucose cotransporter 2 SGLT2i) on differential expression HIF-1α/2α. Tissue prolylhydroxylase 3 (PHD3), a key regulator stability, was also in rat model. Type 1...
Adherens junctions (AJs), together with tight (TJs), form an apical junctional complex that regulates intestinal epithelial cell-to-cell adherence and barrier homeostasis. Within the AJ, membrane-bound E-cadherin binds β-catenin, which functions as essential intracellular signaling molecule. We have previously identified a novel protein in region of junction complex, chloride channel protein-2 (ClC-2), we used to study TJ regulation. In this study, investigated possible effects ClC-2 on...
Vessel Plus is an open acccess journal, which publishes articles related to vascular diseases, including acute respiratory distress syndrome, aneurysm, atherosclerosis, hypertension, stroke, peripheral or pulmonary etc.
Abstract To raise awareness of high blood pressure (BP) levels and associated risk factors among the Sudanese population. A cross-sectional study was conducted in six states during period May–August 2018. The area included public indoor outdoor areas, institutes, service facilities. questionnaire for collecting data employed including demographic data, along with three consecutive BP measurements. Data were collected by trained volunteers. Hypertension (HTN) defined as a systolic ≥140 mmHg...
To assess the role of 1H-magnetic resonance spectroscopy (1H-MRS) in confirmation pathological complete response after neoadjuvant chemotherapy breast cancer.Forty-seven cases (53.72 ± 8.53 years) were evaluated using magnetic imaging (MRI) and 1H-MRS with choline (Cho) signal-to-noise ratio (SNR) measured followed by histopathology ROC analyses.Twelve patients had response, 35 residual disease. Mean age was 53.72 years. The mean tumour size before (NAC) 4.21 0.99 cm NAC 0.9 0.44 cm.Positive...
Abstract Background Lung cancer is one of the leading causes cancer-related mortality worldwide. It frequently metastasizes to bone, brain, lung, and liver, causing a shorter survival. Unusual metastasis also occurs. A few reports have been published, majority described metastatic sites involved gastrointestinal system and, occasionally, thyroid gland. Gastrointestinal from primary lung rare; however, tract as an event frequent. However, distant gland rare for all types tumors. Case...
Objectives: Our aim is to investigate the prevalence of hyperuricemia and its relationships MetS components such as hypertension (HTN), glucose intolerance, obesity hyperlipidemia among Sudanese population. Methods: This a descriptive cross sectional study, held in Khartoum State, Sudan. The study was performed with sample 217, adults, attending clinics set by Society Hypertension on occasion International day from 2016 2017. Using World Health Organization WHO) definition, direct...
Abstract Background Several conditions are associated with esophageal eosinophilia such as eosinophilic esophagitis (EoE) and gastro-esophageal reflux disease (GERD). The aim of this study was to detect the prevalence in patients upper gastrointestinal (GI) symptoms referred for diagnostic GI endoscopy. This included 86 who underwent endoscopy biopsies. Results Esophageal EE found 26 (30.2%): 3 (3.5%) had EoE 23 (26.7%) low-grade eosinophilia. most common presenting were heart burn 84...
Colorectal cancer (CRC) is one of the most prevalent and deadly neoplasms.It develops through several molecular pathways varies in clinical presentation patient prognosis.The prognosis CRC influenced by variable pathologic variables.Understanding basis that promote progression, invasive metastatic features, important for establishing effective therapeutic strategies.Epithelial mesenchymal transition (EMT) regarded to be key hallmark carcinogenesis, providing capacities cells promoting...
Pleural malignancies disturb normal ways of protein metabolism deferring imbalance backside markers in body tissues and fluids see the sights muscle derangement. The aim this work to study depletion catabolism cases with malignant pleural effusion. Thirty patients effusions not under chemotherapy were studied regarding derangement (plasma albumin & potassium levels creatinine height index) radiological signs (the presence thickness by computed tomography (CT) chest wasting skeletal...
Objective: The aim of the current study is to assess impact hyperglycemia and elevated blood pressure on serum lipid profile in Sudanese patients. results will influence monitoring management policies so as avoid complications related hypertension diabetes mellitus. Design Method: This a cross sectional case control conducted Khartoum state, Sudan at 2015. A total 228 participants we enrolled this study. Out them 68 were known hypertensive, 42 diabetics, 24 both hypertensive diabetic 94 sex...
Background Information: Cardiovascular diseases (CVDs) are number one killer in the world among non-communicable (NCDs).The principal underlying risk factor for CVDs is hypertension (HTN).Objectives: To identify prevalence of hypertension, stages HTN and related factors such as age, sex, smoking body mass index (BMI) population Khartoum