A5079183979- Air Quality and Health Impacts
- Allergic Rhinitis and Sensitization
- Ocular Surface and Contact Lens
- Skin Protection and Aging
- Glaucoma and retinal disorders
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Contact Dermatitis and Allergies
- Cancer Diagnosis and Treatment
- Intraocular Surgery and Lenses
- Indoor Air Quality and Microbial Exposure
- Ophthalmology and Eye Disorders
- Head and Neck Cancer Studies
- Endometrial and Cervical Cancer Treatments
- Ocular and Laser Science Research
- Impact of Light on Environment and Health
- Psoriasis: Treatment and Pathogenesis
- Heme Oxygenase-1 and Carbon Monoxide
- Healthcare and Environmental Waste Management
- Education and Digital Technologies
- Liver physiology and pathology
- Air Quality Monitoring and Forecasting
- COVID-19 impact on air quality
- Lung Cancer Treatments and Mutations
- Bladder and Urothelial Cancer Treatments
Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo
2007-2020
University of Michigan
2016-2018
Michigan United
2018
Secretaria Municipal de Saúde
2018
Universidade de São Paulo
2007-2014
National Council for Scientific and Technological Development
2012
Ophthalmology Associates (United States)
2012
Universidade Estadual de Campinas (UNICAMP)
2009
AC Camargo Hospital
2006
Hospital São Paulo
2006
To evaluate the effect of high levels environmental air pollution on tear osmolarity and its possible correlation with clinical signs symptoms.This was a panel study involving 71 taxi drivers traffic controllers from São Paulo, Brazil. Mean individual 24-hour exposure to nitrogen dioxide (NO2) particulate matter smaller than 2.5 μm (PM2.5) were assessed 4 different occasions. On first third visits, subjects submitted evaluations including administration Ocular Surface Disease Index...
Ocular mucosa is exposed constantly to the external environment, and chronic exposure air pollution may affect ocular surface.We assessed effect of on surface by combining determinations individual conjunctival impression cytology.A panel study was conducted with 29 volunteers recruited in two locations different levels: São Paulo (n = 13) Divinolândia 16). We mean levels nitrogen dioxide (NO2) for 7 days, using a passive sampler. Impression cytology samples were obtained from inferior...
To evaluate the effect of diesel exhaust particles (DEP) on viability, proliferation, apoptosis, secretion cytokines (IL-6, IL-8, and TNF-α), mucin gene transcription (MUC1, MUC5AC, MUC16) in human epithelial cells cornea (HCLE) conjunctiva (IOBA-NHC).HCLE IOBA-NHC were incubated with DEP (10-500 μg/mL) for 24 hours. Cell proliferation was evaluated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Apoptotic measured an annexin V-FITC propidium iodide kit flow cytometry....
O presente artigo traz luz acerca da Educação Matemática no Ensino na Básica, tendo como centralidade, conteúdos de ensino unidade temática Estatística Médio, estabelecida pela Base Nacional Comum Curricular (BNCC), do currículo Matemática, a pesquisa é permeada interseccionalidade com à das Relações Étnico-Raciais (ERER), analisadas por meio tratamento estatístico extraídos indicadores especializados recentes Segurança Pública e outros órgãos confiáveis referência nacional maior violência...
Objective: To estimate the prevalence of blindness in elderly population Campinas, Brazil, and to describe coverage quality cataract surgery services area. Methods: A brief assessment (using "RACSS" (Rapid Assessment Cataract Surgical Services Method) was conducted using random cluster sampling, with a sample composed 60 clusters 40 people aged 50 years or older. Visual acuity (VA) measured lens status observed by direct visual ophthalmoscopy. From selected 2,400 subjects, 92.67% were...
Purpose: Orbital fibroblasts from patients with Graves' disease (GD-OF) express many different cytokines when treated bovine thyrotropin (bTSH). The present study aimed to determine why TNF-α cannot be induced by bTSH in GD-OF. Methods: Fibrocytes and GD-OFs were cultivated donors who a busy academic medical center practice. Real-time PCR, Western blot analysis, reporter gene assays, cell transfections, mRNA stability ELISA, flow cytometry performed. Results: We found that induces...
Abstract Dry eye disease (DED) is common in Rheumatoid Arthritis (RA) patients. The application of conjunctival goblet cell count as a clinical biomarker to diagnose and respond treatment can take place rheumatoid arthritis patients under TNF-inhibitors (TNFi) therapy. This study aimed investigate the ocular surface parameters long-term effects TNFi therapy on features At baseline, eligible were compared healthy controls (similar age/gender), regarding Ocular Surface Disease Index (OSDI)...
Abstract Dry eye disease can compromise the patient’s quality of life. Few studies assessed ocular surface (OS) in Ankylosing Spondylitis (AS) patients. This study aimed to evaluate clinical and cytological findings OS patients with AS, classify dry (DED) severity grade conjunctival impression cytology (IC), effects TNF inhibitors (TNFi) a one-year follow-up. A baseline (BL) evaluation included 36 AS 39 healthy controls. They fulfilled Ocular Surface Index Disease questionnaire underwent...
Este artigo explora a integração da abordagem STEAM (Ciência, Tecnologia, Engenharia, Artes e Matemática) na Educação Básica, com foco em metodologias ativas no de Ciências Matemática suas Tecnologias ensino Básica. Objetiva-se nesta presente pesquisa apresentar potencialidades didático-pedagógica metodológica para melhoria do processo aprendizagem nos conteúdos das disciplinas áreas conhecimento citadas; Justifica-se pela demanda por abordagens inovadoras Básica brasileira detrimento...
Atmospheric pollution arising from diesel-powered engines can result in acute and chronic diseases of the respiratory cardiovascular systems. The annual carnival festival that takes place city Salvador, Bahia-Brazil, is a large-scale event gathers approximately 2 m revelers 170,000 workers who accompany dozens sound-trucks, or trios elétricos, for period seven days. These slow-moving sound-trucks run on diesel fuel, constantly exposing those around them to exhaust fumes. present...
Introduction: Developing countries lack the technology to detect and measure levels of air pollution, making it difficult update legislation on quality standards for control emission sources, as well implement surveillance program. Several methodological approaches have been suggested by international agencies, however local context is necessary make adjustments that will result in replicable methods across Brazilian agencies. In Brazil, Ministry Health, through Environmental Health...