A5080591502- Functional Brain Connectivity Studies
- Sleep and related disorders
- Child and Adolescent Psychosocial and Emotional Development
- Attention Deficit Hyperactivity Disorder
- Mental Health Research Topics
- Sleep and Work-Related Fatigue
- Sleep and Wakefulness Research
- Circadian rhythm and melatonin
- Child Abuse and Trauma
- Early Childhood Education and Development
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Psychosocial Factors Impacting Youth
- COVID-19 and Mental Health
- Obstructive Sleep Apnea Research
- Youth Substance Use and School Attendance
- Health and Wellbeing Research
- 3D Shape Modeling and Analysis
- Advanced MRI Techniques and Applications
- Treatment of Major Depression
- Sexual Assault and Victimization Studies
- Brain Tumor Detection and Classification
- Intimate Partner and Family Violence
- Moyamoya disease diagnosis and treatment
- Perfectionism, Procrastination, Anxiety Studies
- Cognitive Abilities and Testing
Seoul National University Hospital
2019-2025
Seoul National University
2020-2025
Boramae Medical Center
2025
National University College
2024
New Generation University College
2024
Eulji University
2024
Importance Selective serotonin reuptake inhibitors (SSRIs) are considered a first-line pharmacological treatment for adolescent depression with moderate or higher levels of symptom severity. Thus, it is important to understand neurobiological changes related SSRIs during the course adolescents depression. Objective To examine associated SSRI in major depressive disorder (MDD) by measuring longitudinal volume and resting-state functional connectivity (rsFC) dorsolateral prefrontal cortex...
We examined the neural basis of emotion regulation in shift workers, and relationships between regulation, mood, sleep disturbance 24-h rest-activity rhythm (RAR). Fifty-six workers (SW) with non-standard schedules 52 controls (CON) participated this study. They completed self-reported measures mood problems, kept a diary, wore wrist actigraphy device to assess RAR. underwent one-night polysomnography were scanned while performing an task. group differences correlations neural, RAR...
Abstract Background Academic performance is an important issue for Korean students. Various psychological factors contribute to academic performance. We aimed evaluate the that affect integratively. Methods A total of 102 high achievers and 120 comparison participants were recruited. evaluated (test anxiety, perfectionism, personality traits, resilience, self-efficacy) measured using College Scholastic Ability Test current college grade. compared between achiever groups. Multiple linear...
Abstract Literature suggests that neurobiological factors such as brain structure play an important role in linking social stress with depression adolescence. We aimed to examine the of subcortical volumetric alteration association between peer problems one type and adolescent depression. hypothesized there would be indirect effects on through alteration. Seventy eight adolescents major depressive disorder (MDD) (age mean [SD] = 14.9 ± 1.5, 56 girls) 47 healthy controls [14.3 1.4, 26 girls])...
Cognitive behavioral therapy for insomnia (CBTi) is the first-line chronic insomnia. Mobile app-based CBTi (MCBTi) can enhance accessibility of treatment; however, few studies have evaluated effectiveness MCBTi using a multicenter, randomized controlled trial design.
Abstract Background The objective of this study is to investigate the direct and indirect effects childhood trauma, internalizing symptoms, externalizing symptoms on suicidality among adolescents, thereby establishing a structural equation model. Methods present uses cross-sectional descriptive design. Among 147 adolescents aged 12–17, 93 outpatients diagnosed with major depressive disorder 54 controls were included in study. They completed Early Trauma Inventory Self-Report (Short Form)...
In this review, we provide information about the etiology, risk factors, and clinical presentations of maltreatment to help clinicians better understand child abuse neglect. Child is a major global health challenge that can result in severe consequences. Abused neglected children are likely develop psychiatric disorders, such as depressive disorder, anxiety posttraumatic stress disorder. Understanding expected prevent reduce victimization children, adolescents, their families.
This study investigated alterations in resting-state functional connectivity (RSFC) and hyperarousal biomarkers patients with chronic insomnia disorder (CID), compared good sleepers (GS). We also examined the relationships between altered RSFC biomarkers. Fifty CID 52 GS completed self-reporting questionnaires, then underwent polysomnography magnetic resonance imaging. analyzed amygdala (AMG) anterior insula (aINS), which are core regions of salience network that likely to be involved...
Due to the vast array of NeRF-based techniques, representation power Neural Radiance Fields (NeRF) has been quickly rising in recent years. However, it is still difficult offer fresh perspectives for user-controlled geometry alterations with current techniques; instead, they restrict edits those that were observed during training or particular regions chosen by provider. In this paper, we present NeRFlex, Flexible Diffeomorphic Deformation, which lets users process completely unrestricted...
This study aimed to examine the association between normal-but-low folate levels and cognitive function in elderly population using a prospective cohort study.We analyzed 3,910 participants whose serum were within normal reference range (1.5-16.9 ng/mL) at baseline evaluation population-based named "Korean Longitudinal Study on Cognitive Aging Dementia." The quartile categories disorders [mild impairment (MCI) or dementia] was examined binary logistic regression analysis adjusting for...
Background Studies on the brain structures of shift workers are limited; thus, this cross-sectional study aimed to compare and structural correlates subjective sleepiness insomnia symptoms between non-shift workers. Methods Shift ( n = 63) 58) completed questionnaires assessing symptoms. Cortical thickness, cortical surface area, subcortical volumes were measured by magnetic resonance imaging. The morphometric measures compared groups, interaction analyses using as dependent variable...
Abstract Background The aim of this study was to examine the psychometric properties Korean version Screen for Child Anxiety Related Emotional Disorders (SCARED) on a sample youths and cross-cultural differences in adolescents’ anxiety. Methods Our included 147 adolescents (ages 12–17, 92 girls), 93 with major depressive disorder 54 as controls. Participants were evaluated using Kiddie-Schedule Affective Schizophrenia School-Age Children-Present Lifetime Version (K-SADS-PL), SCARED, Behavior...
Abstract Study Objectives This study compared resting-state functional connectivity (rsFC) of the salience network (SN) between rotating shift workers (RSWs) and controls. Furthermore, we examined whether rsFC SN was correlated with sleep, emotion, cognition, attention. Methods The 60 RSWs 57 controls enrolled in this completed self-report questionnaires sleep diaries to assess subjective quality, polysomnography actigraphy evaluate objective 24-hour rest-activity rhythm parameters....
Objective This study aimed to develop a brief self-report measure of depressive and anxiety symptoms in victims sexual violence.Methods The sample, which consisted 215 255 healthy controls, was recruited between December 2016 November 2018 from eight Sunflower Centers. Eligible items were selected existing scales depression (CES-DC CES-D) (SAI-C BAI) by item-total correlation coefficients item response theory (IRT) analysis. Internal consistency computed the receiver operating...
Abstract Introduction Obstructive sleep apnea (OSA) has been known to be associated with increased cardiovascular, metabolic diseases and mortality. As few studies reported factors on relationship between OSA mortality, we aimed investigate all-cause mortality in patients. Methods We performed retrospective study group of 1547 subjects who referred the Center for Sleep Chronobiology, Seoul National University Hospital, from June 2004 December 2013. Subjects had other disorders including...
Abstract Introduction This study investigated the altered neural activation underlying emotional interference and its role in linking sleep disturbance insomnia disorder. Methods Thirty-four patients (female 73.53%, mean age 50.76±11.98 years) 33 controls 63.64%, 42.73±11.90) were included this study. They completed self-reported questionnaires (Pittsburgh Sleep Quality Index (PSQI), Insomnia Severity (ISI), Epworth Sleepiness Scale (ESS), Dysfunctional Beliefs Attitudes about (DBAS)) to...
Abstract Introduction Shift work is associated with sleep disturbance, mood problems, and quality of life. Sleep reactivity, a trait-like characteristic reflecting how stress disrupts sleep, related to insomnia, depression, shift-work disorder. We aim investigate the relationship between reactivity shift work, exploring associations symptoms, or life in workers. Methods Seventy workers (SW, 55 females, 30.47±5.90 years old) 54 healthy controls (HC, 36 31.76±6.59 participated current study....
Abstract Introduction Shift workers (SW) commonly experience mood symptoms, which is known to be linked sleep disturbances and disrupted 24-hour rest-activity rhythm (RAR). Altered brain response sleep-related sound (SS) were reported associated with dysfunctional appraisals of disturbances. In current study, we aimed investigate differences in activity SS between SW control participants (CON). Furthermore, explored the moderation effects on relationships daytime sleepiness, symptoms RAR SW....
Summary This study investigated the altered neural activation underlying cognitive control under emotional and sleep‐related interference conditions its role in subjective sleep disturbance patients with chronic insomnia disorder. In total, 48 disorder, age‐, sex‐ body mass index‐matched controls were included this study. They completed self‐reported questionnaires to assess distress. A diary was used evaluate parameters. All participants performed Stroop task (three blocks each of negative...
3D MRI imaging is based on a number of sequences such as T1, T2, T1ce, and Flair, each them performed by group two-dimensional scans. In practical MRI, some scans are often missing while many medical applications require full set An imputation method presented, which synthesizes Key components in this the index registration intensity registration. The models anatomical differences between two different same sequence, reflects image contrast index. Two fields learned to be invariant,...