François‐Xavier Ageron

ORCID: 0000-0003-0520-3619
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About
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Research Areas
  • Trauma and Emergency Care Studies
  • Emergency and Acute Care Studies
  • Cardiac Arrest and Resuscitation
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Abdominal Trauma and Injuries
  • Blood transfusion and management
  • Pelvic and Acetabular Injuries
  • Healthcare Systems and Practices
  • Health, Medicine and Society
  • Injury Epidemiology and Prevention
  • Acute Myocardial Infarction Research
  • Heart Failure Treatment and Management
  • Trauma Management and Diagnosis
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Pain Management
  • Gastrointestinal Bleeding Diagnosis and Treatment
  • Gastrointestinal disorders and treatments
  • Balance, Gait, and Falls Prevention
  • Congenital Diaphragmatic Hernia Studies
  • Anesthesia and Sedative Agents
  • Disaster Response and Management
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Pain Management and Opioid Use
  • Ultrasound in Clinical Applications
  • Nursing Roles and Practices

University of Lausanne
2020-2025

University Hospital of Lausanne
2020-2024

Université Grenoble Alpes
2024

Hôpital Orthopédique de la Suisse Romande
2022

Centre Hospitalier Annecy Genevois
2012-2021

London School of Hygiene & Tropical Medicine
2017-2021

University of London
2020

Assistance Publique – Hôpitaux de Paris
2020

Hôpital Raymond-Poincaré
2020

Hôpital Privé Guillaume de Varye
2020

<h3>Importance</h3> The association between total prehospital time and mortality in physician-staffed trauma systems remains uncertain. <h3>Objective</h3> To describe the of in-hospital prehospital, France, with hypothesis that is associated increased mortality. <h3>Design, Setting, Participants</h3> This cohort study was conducted from January 2009 to December 2016. Data for this were derived 2 distinct regional registries France (1 urban 1 rural) both have a emergency medical service....

10.1001/jamasurg.2019.3475 article EN JAMA Surgery 2019-09-25

Pre-hospital triage is a key element in trauma system that aims to admit patients the most suitable center, and may decrease intra-hospital mortality. We evaluated performance of pre-hospital procedure regional through measurements quality medical assessment efficacy protocol.Our included 13 hospitals categorized as Level I, II or III centers according their technical facilities. Each patient was graded A, B C by an emergency physician, seriousness injuries at presentation on scene. The...

10.1186/s13054-015-0835-7 article EN cc-by Critical Care 2015-03-09

Women are less likely than men to receive some emergency treatments. This study examines whether the effect of tranexamic acid (TXA) on mortality in trauma patients varies by sex and receipt TXA sex.First, we conducted a sex-disaggregated analysis data from Clinical Randomisation an Antifibrinolytic Significant Haemorrhage (CRASH)-2 CRASH-3 trials. We used interaction tests determine treatment varied sex. Second, examined Trauma Audit Research Network (TARN) explore differences TXA. logistic...

10.1016/j.bja.2022.03.032 article EN cc-by-nc-nd British Journal of Anaesthesia 2022-05-18

Early and accurate detection of severe hemorrhage is critical for a timely trigger massive transfusion (MT). Hemodynamic indices combining heart rate (HR) either systolic (shock index [SI]) or pulse pressure (PP) (PP/HR ratio) have been shown to track blood loss during hemorrhage. The present study assessed the accuracy prehospital SI PP/HR ratio predict subsequent MT, using gray-zone approach.This was retrospective analysis (January 1, 2009, December 31, 2011) prospectively developed trauma...

10.1097/ta.0000000000001191 article EN Journal of Trauma and Acute Care Surgery 2016-08-09

Abstract Background Little is known about the effect of under triage on early mortality in trauma a pediatric population. Our objective to describe 24-h after major regional system. Methods This cohort study was conducted from January 2009 December 2017. Data were obtained registry Northern French Alps Trauma System. The network guidelines patients according an algorithm shared with adult patients. Under defined by number that required specialized care transported non-level I center total...

10.1186/s13017-020-00345-w article EN cc-by World Journal of Emergency Surgery 2021-01-07

Abstract Background The Abbreviated Injury Scale (AIS) and Severity Score (ISS) grade the severity of injuries are useful for trauma audit benchmarking. However, AIS coding is complex requires specifically trained staff. A simple yet reliable scoring system needed. aim this study was two-fold. First, to develop validate a simplified (sAIS) chart centred on most frequent use by non-trained healthcare professionals. Second, evaluate diagnostic accuracy sAIS (index test) calculate ISS (sISS)...

10.1186/s13049-025-01320-7 article EN cc-by Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 2025-01-29

Purpose of review This aims to provide a perspective on fluid resuscitation strategies and emerging trends in deresuscitation, with particular emphasis stewardship, monitoring, personalized management. Recent findings studies underscore paradigm shift strategies. Notably, aggressive plasma volume expansion has been linked higher morbidity mortality, favoring conservative resuscitation. Dynamic parameters, such as pulse pressure variation (PPV) stroke (SVV) outperform static markers like...

10.1097/mcc.0000000000001267 article EN Current Opinion in Critical Care 2025-03-07

Upper gastrointestinal bleeding (UGB) is common in emergency departments (EDs) and can be caused by many eso-gastro-duodenal lesions. Most available epidemiological data on the management of UGB comes from specialized (intensive care units or gastroenterology departments), but little known ED perspective. We aimed to determine distribution symptoms revealing EDs hemorrhagic lesions identified endoscopy. also describe characteristics patients consulting for UGB, outcomes. This was a...

10.1186/s13049-017-0425-6 article EN cc-by Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 2017-08-14

Background Intravenous morphine (IVM) is the most common strong analgesic used in trauma, but associated with a clear time limitation related to need obtain an access route. The intranasal (IN) route provides easy administration fast peak action due high vascularization and absence of first-pass metabolism. We aimed determine whether IN sufentanil (INS) for patients presenting emergency department acute severe traumatic pain results reduction intensity non-inferior IVM. Methods findings In...

10.1371/journal.pmed.1002849 article EN cc-by PLoS Medicine 2019-07-16

Importance Hemorrhagic shock is a common cause of preventable death after injury. Vasopressor administration for patients with blunt trauma and hemorrhagic often discouraged. Objective To evaluate the association early norepinephrine 24-hour mortality among shock. Design, Setting, Participants This retrospective, multicenter, observational cohort study used data from 3 registries in US France on all consecutive January 1, 2013, to December 31, 2018. Patients were alive admission shock,...

10.1001/jamanetworkopen.2022.34258 article EN cc-by-nc-nd JAMA Network Open 2022-10-07

Upper gastrointestinal bleeding (UGIB) presents a high incidence in an emergency department (ED) and requires careful evaluation of the patient's risk level to ensure optimal management. The primary aim this study was externally validate compare performance Rockall score, Glasgow-Blatchford score (GBS), modified GBS AIMS65 predict death need for intervention among patients with UGIB. This cross-sectional observational consulting ED Swiss tertiary care hospital Primary outcomes were...

10.1097/mej.0000000000000983 article EN European Journal of Emergency Medicine 2022-11-10

Tranexamic acid reduces surgical blood loss and deaths from bleeding in trauma patients. must be given urgently, preferably by paramedics at the scene of injury or ambulance. We developed a simple score (Bleeding Audit Triage Trauma score) to predict death bleeding.We conducted an external validation BATT using data UK Research Network (TARN) 1st January 2017 31st December 2018. evaluated impact tranexamic treatment thresholds patients.We included 104,862 patients with severity 9 above. was...

10.1186/s13049-020-00827-5 article EN cc-by Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 2021-01-06

Early identification of bleeding at the scene an injury is important for triage and timely treatment injured patients transport to appropriate facility. The aim study compare performance different scores.We examined data from Swiss Trauma Registry years 2015-2019. includes with major trauma (injury severity score (ISS) ≥ 16 and/or abbreviated scale (AIS) head 3) admitted any level-one centre in Switzerland. We evaluated ABC, TASH Shock index (SI) scores, used predict massive transfusion (MT)...

10.1186/s13054-022-04178-8 article EN cc-by Critical Care 2022-09-28

AimsThe end-tidal carbon dioxide (ETCO2) is frequently measured in cardiac arrest (CA) patients, for management and predicting survival. Our goal was to study the PaCO2 ETCO2 hypothermic patients.MethodsWe included patients with refractory CA assessed extracorporeal cardiopulmonary resuscitation. Hypothermic were identified from previously prospectively collected data Poland, France Switzerland. The non-hypothermic two French cohort studies. primary parameters of interest at hospital...

10.1016/j.resuscitation.2022.01.022 article EN cc-by Resuscitation 2022-01-31

The relationship between fibrinogen concentration and traumatic death has been poorly explored after severe trauma. Existing studies analysed this in unselected trauma population, often considering as a categorical variable. aim of our study was to model the in-hospital mortality patients requiring massive transfusion using on admission continuous We designed retrospective observational based prospectively collected data from 2009 2015 seven French level-I centres. All consecutive at least...

10.1186/s13049-018-0523-0 article EN cc-by Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 2018-07-09
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