A5019799308- Research on Leishmaniasis Studies
- Trypanosoma species research and implications
- Water resources management and optimization
- Medicinal Plant Research
- Reservoir Engineering and Simulation Methods
- Parasites and Host Interactions
- Antibiotic Resistance in Bacteria
- Pharmacological Effects of Natural Compounds
- Hydrology and Watershed Management Studies
- Insect Pest Control Strategies
- Antimicrobial agents and applications
- Congenital Anomalies and Fetal Surgery
- Parasitic Infections and Diagnostics
- Biochemical effects in animals
- Insect symbiosis and bacterial influences
- Parasitic infections in humans and animals
- Eosinophilic Disorders and Syndromes
- Synthesis and Biological Evaluation
- Insect behavior and control techniques
- Bacterial biofilms and quorum sensing
Pasteur Institute of Iran
2020-2025
Mazandaran University of Medical Sciences
2024
Payame Noor University
2013
Isfahan University of Technology
2009
Abstract Background The characterization of Leishmania species is important for clinical management the diseases and epidemiological control parasite distribution. Most published polymerase chain reaction (PCR) amplification methods lack ability to identify all complexes, have low performance usually need post-PCR procedures. There a improving diagnosis CL by development an accurate affordable PCR method in specimens. Methods We designed optimized amplifying internal transcribed spacer 2...
Abstract The CRISPR/Cas9 system has emerged as a powerful tool for precise genome editing, allowing the deletion of genes, generation point mutations, and addition tags to endogenous genes. We employed an efficient technique in Leishmania major assess its efficiency editing kDNA-associated gene, universal minicircle sequence binding protein (UMSBP), which is involved mitochondrial respiration kinetoplast division. generated UMSBP C-tagged single knockout L. ( Lm +/− ) parasites using...
Abstract Background Anthroponotic cutaneous leishmaniasis (ACL) due to Leishmania tropica and zoonotic CL (ZCL) L major have different clinical epidemiological features. Objectives To determine whether pro‐inflammatory cytokines are involved in diverse pathogenicity of species causing CL. Patients/Methods The capacity major/L modulate expression IL‐1β, IL‐8 (CXCL8), IFN‐γ, TNF‐α MCP‐1 (CCL2) peripheral blood mononuclear cells (PBMCs) monocyte‐derived macrophages (MDMs) was evaluated by...
Abstract Background and aims Acinetobacter baumannii is among the most concerning cause of nosocomial infections due to its high level antibiotic resistance mortality. The aim this study was determine role efflux pumps in A. strains three disinfectants, including MICROZED ID‐MAX, NANOSIL D2, OPIDEX OPA. Methods Twenty‐eight environmental clinical isolates were collected from selected hospitals central Iran. minimum inhibitory concentrations disinfectants determined real time reverse...
Introduction:: Cystic echinococcosis (CE) is a zoonotic parasitic disease caused by the metacestode of Echinococcus granulosus. CE health problem in Middle Eastern countries, such as Iran. The purpose this study was to purify subunit 8 KDa antigen B from crude sheep hydatid cyst fluid (HCF) and compare its sensitivity specificity with commercial human ELISA kit (PT-Hydatid-96). Methods:: 28 sera samples were collected patients who had surgery for their confirmed pathology after surgery....
The infectious inoculum of a sand fly, apart from its metacyclic promastigotes, is composed factors derived both the parasite and vector. Vector-derived factors, including salivary proteins gut microbiota, are essential for establishment enhancement infection. However, type number bacteria egested during salivation unclear. In present study, flies Phlebotomus papatasi were gathered three locations in hyperendemic focus zoonotic cutaneous leishmaniasis (ZCL) Isfahan Province, Iran. By using...