The triglyceride glucose (TyG) index, a product of and fasting glucose, is reliable marker for insulin resistance (IR). Obesity also known to be closely related with IR. Recently, the efficiency TyG-related markers that combine obesity TyG index has been studied; however, earlier studies were limited in number results inconsistent. Therefore, this study, we investigated several combinations indices, namely, body mass (BMI), waist circumference (WC), waist-to-height ratio (WHtR), reflecting...

β-Caryophyllene (trans-4,11,11-trimethyl-8-methylenebicyclo[7,2,0]undec-4-ene), found in various plants, is a natural bicyclic sesquiterpene with low toxicity. Here, we show that single intraperitoneal injection of β-caryophyllene (10 mg/kg) significantly reduced the cortical infarct volume by 67% when given immediately before middle cerebral artery occlusion (MCAO). Neurological deficits caused MCAO were also decreased β-caryophyllene. treatment cells exposed to oxygen–glucose deprivation...

Background: Interleukin-17 (IL-17)-producing T helper (Th) 17 cells are considered as a new subset of critical to the development rheumatoid arthritis (RA).We aimed investigate distribution Th1 and Th17 their association with disease activity, determine Th17-related cytokine levels in peripheral blood RA patients.Methods: Peripheral mononuclear from 55 20 osteoarthritis (OA) patients were stimulated mitogen, distributions CD4 + Interferon (INF) IL-17 - (Th1 cells) INF-IL-17 (Th17 examined by...

Rapid screening of urinary tract infection is important to determine antibiotic treatment and reduce unnecessary urine culture. We evaluated the performance new flow cytometry-based UF-5000 automated analyzer (Sysmex, Kobe, Japan). A total 1,430 samples from 1,226 patients were analyzed compared cultures which a Previ Isola (bioMérieux, Marcy l'Etoile, France) system was applied. In total, 878 (61.4%) produced ≥103 CFU/ml bacterial growth (309 with Gram-negative [GN] bacteria, 517...

Ye Won Jung, M.D., Dan Bit Park, Suk Jeong An, Su Min Chung, Byung Hun Kang, Heon Jong Yoo, Mina Lee, Ji Myung Kim, M.D.. Lab Med Online 2024;14:82-9. https://doi.org/10.47429/lmo.2024.14.2.82

Summary Because serum ferritin and transferrin saturation (TS) have a limitation in estimating iron status haemodialysis patients, the reticulocyte haemoglobin content (CHr) has been proposed as new tool. We investigate accuracy of CHr comparison with conventional tests relationship between changes levels after therapy. selected 140 patients receiving rHuEPO intravenous supplementation measured their complete blood count, parameters. Iron deficiency was defined <100 μ g/l and/or TS...

Bacterial meningitis is an infectious disease with high rates of mortality and frequency severe sequelae. Early identification causative bacterial viral pathogens important for prompt proper treatment prevention life-threatening clinical outcomes. In the present study, we evaluated value Seeplex Meningitis ACE Detection kit (Seegene Inc., Korea), a newly developed multiplex PCR employing dual priming oligonucleotide methods, diagnosing acute meningitis.Analytical sensitivity was studied...

S-Allyl-L-cysteine (SAC) has been shown to reduce ischemic injury due its antioxidant activity. However, the property of SAC controversial. The present study investigated neuroprotective mechanism in cerebral insults. decreased size infarction after transient or global While it did not alter N-methyl-D-aspartate excitotoxicity, significantly scavenged endogenously exogenously produced ONOO- and reduced cytotoxicity. In contrast, much lower scavenging activity against H2O2, O2*(-) NO....

Ji Youn Sung, Kye Chul Kwon, M.D., Jong Woo Park, Yeon Suk Kim, Myung Kyeong Seob Shin, Wan Chi Seon Ko, So Jeong Hoon Song, and Sun Hoe Koo, M.D.. Korean J Lab Med 2008;28:16-23. https://doi.org/10.3343/kjlm.2008.28.1.16

The objective of this survey was to gain a real-world perspective on coagulation testing by evaluating the availability various laboratory tests, assessing specific analytic and postanalytic steps in clinical laboratories Korea.Participants were surveyed using 65-question questionnaire specifically focused their practices related prothrombin time (PT), activated partial thromboplastin (aPTT), plasma-mixing studies, lupus anticoagulant (LA) platelet function factor assays, composition...

Syndecan-1 is a heparan sulfate proteoglycan expressed on plasma cells, especially myeloma and can exist in serum as soluble syndecan-1 after shedding from the cell surface. Soluble has been suggested to promote growth be an independent prognostic factor for multiple myeloma. We aimed evaluate effect of levels at time diagnosis during therapy therapeutic response prognosis patients with myeloma.We analyzed 28 50 normal controls, compared its Durie-Salmon stage other markers In addition, we...

The authors generate and compress short pulses via the ground excited state transitions from a passively mode-locked grating coupled quantum dot two-section diode laser at repetition rate of 2.7GHz. selection isolation either or transition were performed by an angle tuning grating. externally compressed pulse widths are 970fs 1.2ps transition. sign chirp is up chirped for both transitions.

S-Allyl-L-cysteine (SAC), an active organosulfur compound derived from garlic, was found to reduce mortality with lesser incidence of stroke and also lower the overall stroke-related behavioral score in stroke-prone spontaneously hypertensive (SHRSP) rats by dietary administration. Consequently, anti-stroke effect SAC demonstrated SHRSP rats.

Abstract Background : The diagnosis of septic arthritis (SA) relies on synovial analysis and conventional culture. But, these methods lack sensitivity culture is time consuming to establish a definite diagnosis. This study evaluated new multiplex PCR assay which entailed screening for Gram typing identification species using two primer mixes. Methods A total 80 fluid samples from patients with suspected SA were collected. Culture, PCR, 16S rRNA gene performed. Results analytical was 10 1...

Jeong Hoon Song, M.D., Ji Youn Sung, Ph.D., Kye Chul Kwon, Jong Woo Park, Hye Hyun Cho, B.S., So Yeon Shin, Young Ko, Myung Kim, Kyeong Seob and Sun Hoe Koo, M.D.. Korean J Lab Med 2010;30:295-300. https://doi.org/10.3343/kjlm.2010.30.3.295

The purpose of this study was to investigate dietary behaviors and nutritional knowledge among immigrant women in multicultural families. In addition, reveals a necessity for nutrition education, which is apparent both living families as well education experts. survey conducted with 30 within Seoul. the were significantly different by their period residence. longer they had resided Korea, higher behavior score. However, there no significant difference This also indepth personal interviews 8...

The gold standard for assessing pubertal activation is the gonadotropinreleasing hormone (GnRH) stimulation test (GnRHST), which invasive, timeconsuming, and inconvenient. This study evaluated whether a single random measurement of urinary luteinizing (LH) concentration could substitute GnRHST in diagnosing monitoring central precocious puberty (CPP) girls.Fifty-five girls with breast buds before 8 years age were assessed by both gonadotropin assays. Based on results, 29 assigned to CPP...

We investigate the spectral linewidth of a monolithic photonic crystal nanocavity laser. The laser is based on buried heterostructure cavity in which an ultra-small InGaAsP active region embedded InP crystal. Although it was difficult to achieve narrow operation previously reported lasers, we have successfully demonstrated 143.5 MHz, far narrower than cold and narrowest value yet for nanolasers lasers. accompanied by low power consumption ultrasmall footprint, thus making this particular...