- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Liver Disease Diagnosis and Treatment
- Intestinal Malrotation and Obstruction Disorders
- Gastrointestinal disorders and treatments
- Gastroesophageal reflux and treatments
- Inflammatory Bowel Disease
- Clinical Nutrition and Gastroenterology
- Gastrointestinal motility and disorders
- Liver Diseases and Immunity
- Microscopic Colitis
- Esophageal and GI Pathology
- Pancreatitis Pathology and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Renal Transplantation Outcomes and Treatments
- Transplantation: Methods and Outcomes
- Infant Nutrition and Health
- Congenital Diaphragmatic Hernia Studies
- Vaccine Coverage and Hesitancy
- Airway Management and Intubation Techniques
- Gastrointestinal Bleeding Diagnosis and Treatment
- Congenital Heart Disease Studies
- Foreign Body Medical Cases
- Genetic and Kidney Cyst Diseases
Children's Hospital of Los Angeles
2014-2025
University of Southern California
2018-2021
Loma Linda University
2004-2015
Loma Linda University Children's Hospital
2004-2015
Loma Linda University Medical Center
2006-2014
University of California, Los Angeles
1998-2001
Kaiser Foundation Hospital
1998
Kaiser Permanente
1998
VA Sepulveda Ambulatory Care Center
1995
UCLA Medical Center
1991
Fontan-associated liver disease (FALD) has emerged as an important morbidity following surgical palliation of single ventricle congenital heart disease. In this study, non-invasive biomarkers that may be associated with severity FALD were explored.A retrospective cohort paediatric patients post-Fontan who underwent biopsy at a high volume centre was reviewed.Among 106 patients, 66% male and 69% Hispanic. The mean age 14.4 ± 3.5 years, performed 10.8 3.6 years post-Fontan. BMI 20.8 5 kg/m2,...
Importance Live vaccines (measles-mumps-rubella [MMR] and varicella-zoster virus [VZV]) have not been recommended after solid organ transplant due to concern for inciting vaccine strain infection in an immunocompromised host. However, the rates of measles, mumps, varicella are rising nationally internationally, leaving susceptible children at risk life-threating conditions. Objective To determine safety immunogenicity live pediatric liver kidney recipients. Design, Setting, Participants This...
This cohort study assesses the protection provided by live attenuated viral vaccines among a pediatric population of solid organ transplant recipients 1 year after vaccination.
Liver transplantation (LT) in young patients is being performed with greater frequency. We hypothesized that objective analysis of pre-, intra-, and postoperative events would help understand contributors to successful outcomes guide transplant decision processes. queried SPLIT registry for pediatric transplants between 2011 2018. Outcomes were compared age groups: 0-<3, 3-<6, 6-<12 months, 1-<3 years (Groups A, B, C, D respectively) by weight categories: <5, 5-10, >10 kg; 1033 available...
Background. Autoimmune hepatitis (AIH) and cryptogenic chronic (CCH) are important causes of liver failure in children, frequently necessitating orthotopic transplantation (OLT). The aim this study is to review disease progression potential differences between subgroups children with AIH CCH. Methods. medical records 65 diagnosed or CCH 1980 1998 were evaluated. Results. median age at presentation was 9 years, 8 months (range 4 months–19 years), the follow-up period years 3 months–18 10...
Although pediatric liver transplantation (LT) results in excellent long‐term outcomes, a high incidence of early acute cellular rejection and late graft fibrosis persists. Routine measurement allograft enzymes may not reliably detect episodes, identify candidates for immunosuppression minimization, or indicate fibrosis. Surveillance biopsies (SBs) can provide valuable information this regard, but their role LT is fully established. A retrospective cohort 236 recipients from high‐volume...
Abstract HPS is a significant complication of portal hypertension in children with chronic liver disease and an established indication for LT . It characterized clinically by the triad pulmonary vascular dilatation causing hypoxemia setting advanced disease. NRH , cause non‐cirrhotic hypertension, diffuse benign transformation hepatic parenchyma into small regenerative nodules minimal or no fibrosis. Development pediatric recipients has not been reported, although occasional cases have...
Alcohol-associated hepatitis (AH) refers to liver injury from alcoholic intake that usually occurs after years of heavy alcohol abuse. Frequent, consumption causes hepatic inflammation, fibrosis, and cirrhosis. Some patients develop severe AH, which carries high short-term mortality is the second most common reason for adult transplants (LTs) worldwide. We present one first cases a teenager diagnosed with AH led LT evaluation. Our patient was 15-year-old male who presented epistaxis 1 month...
Pediatric liver transplant (LT) recipients of maternal living donor (LLD) grafts have been reported to experience fewer rejection episodes. However, it is unclear whether this benefit translates reduction in developing donor-specific antibody (DSA) among maternal-LLD recipients. The aim study was compare immunologic outcomes maternal-LLD, non-maternal-LLD, and deceased (DDLT) recipients.Children (≤18 years) who underwent LT between 1/1998 12/2019 at two high-volume centers North America were...
Purpose: GJT for enteral feeding is increasingly utilized in children with various disorders. There paucity of data about frequency and methods replacement. We describe our experience disorder/intolerance. Methods: Retrospective chart review patients who had at institution from 10/01/07 to 10/31/08 was performed. Initial conversion gastrostomy tube (GT) done by either 1) Esophagogastroduodenoscopy (EGD) OR 2) gastroduodenoscopy through (GD) guidewire (GW). Replacement existing accomplished...
Living donor liver transplantation is an effective means to decrease organ shortage. However, many potential living donors are currently being denied due ABO incompatibility or inadequate volume. Liver paired exchange (LPE) provides a practical solution overcome these obstacles, and yet the first case of LPE in United States was only recently reported 2020. Here, we report world's involving pediatric adult recipients avoid surgical complexity recipient increase graft-to-recipient weight...