A5080332461- Fibroblast Growth Factor Research
- Sulfur Compounds in Biology
- Advanced Glycation End Products research
- Dermatologic Treatments and Research
- Wound Healing and Treatments
- Mast cells and histamine
Affiliated Hospital of Nantong University
2022-2024
Nantong University
2022-2024
Keloid is a common dermatofibrotic disease with excessive skin fibroblast proliferation. Hydrogen sulfide (H2S) as the third gasotransmitter improves fibrosis of various organs and tissues. Our study aimed at investigating effects possible mechanisms H2S on Scar tissues from six patients keloid discarded tissue normal control were collected after surgery, respectively. Plasma content production in measured. fibroblasts transforming growth factor-β 1- (TGF-β 1, 10 ng/mL) stimulated pretreated...
Abstract An excessive proliferation of skin fibroblasts usually results in different fibrotic diseases. Hydrogen sulphide (H 2 S) is regarded as an important endogenous gasotransmitter with various functions. The study aimed to investigate the roles and mechanisms H S on primary mice proliferation. Cell collagen synthesis were assessed expression α‐smooth muscle actin (α‐SMA), proliferating cell nuclear antigen (PCNA), Collagen I III. degree oxidative stress was evaluated by dihydroethidium...