María José Ramírez‐Lázaro

ORCID: 0000-0003-0534-6070
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About
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Research Areas
  • Helicobacter pylori-related gastroenterology studies
  • Microscopic Colitis
  • MicroRNA in disease regulation
  • Cancer-related molecular mechanisms research
  • Gastric Cancer Management and Outcomes
  • Eosinophilic Esophagitis
  • RNA Interference and Gene Delivery
  • Veterinary medicine and infectious diseases
  • Molecular Biology Techniques and Applications
  • Inflammatory Bowel Disease
  • Microbial Metabolites in Food Biotechnology
  • Mycobacterium research and diagnosis
  • Gastrointestinal disorders and treatments
  • Circular RNAs in diseases
  • Gastroesophageal reflux and treatments

Corporació Sanitària Parc Taulí
2009-2024

Institute of Research and Innovation Parc Tauli
2023-2024

Universitat Autònoma de Barcelona
2010-2023

Deleted Institution
2010-2018

Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2009-2018

Instituto de Salud Carlos III
2009-2018

Centro de Investigación Biomédica en Red
2015

Despite many changes, no large studies comparing the different diagnostic tests for Helicobacter pylori have been performed in past 10 years. In this time, monoclonal stool antigen immunoassays and in-office 13C-urea breath (UBTs) appeared. The aim of study was to evaluate accuracy invasive noninvasive a series dyspeptic patients.A total 199 patients who had not previously treated H. infection were prospectively enrolled. Noninvasive analyses included commercial infrared-based UBT...

10.1086/598198 article EN Clinical Infectious Diseases 2009-04-15

Abstract Background: Introduction The epidemiologic status of pediatric inflammatory bowel disease (PIBD) has not been widely studied in Western Europe. prevalence and incidence trends the are largely unknown. aim this study is to determine PIBD its mortality rate Catalonia period 2011-2023. Methods: Material methods A longitudinal was performed using population-based data from Catalan Health Surveillance System (CHSS). Data on prevalence, IBD patients under age 18 years were obtained....

10.1093/ecco-jcc/jjae190.1426 article EN Journal of Crohn s and Colitis 2025-01-01

Background. Well-devised studies comparing new but different monoclonal fecal tests for diagnosing Helicobacter pylori infection are scarce. The objective of this study was to compare the diagnostic accuracy 3 stool tests: 2 rapid in-office tools—RAPID Hp StAR and ImmunoCard STAT! HpSA—and an enzyme immunoassay test—Amplified IDEIA StAR—for H. prior eradication treatment. Methods. Diagnostic reliability evaluated in 199 untreated consecutive patients with dyspeptic symptoms. gold standard...

10.1086/649860 article EN Clinical Infectious Diseases 2009-12-31

Abstract Background: Studies comparing new monoclonal fecal tests for evaluating cure of Helicobacter pylori infection after treatment are scarce. The objective was to compare the diagnostic accuracy three stool tests: two rapid in‐office tools – RAPID Hp StAR and ImmunoCard STAT! HpSA an EIA test Amplified IDEIA StAR. Materials methods: Diagnostic reliability evaluated in 88 patients at least 8 weeks H. treatment. Readings immunochromatographic were performed by different observers....

10.1111/j.1523-5378.2010.00757.x article EN Helicobacter 2010-05-07

Laboratory-based chemiluminescence immunoassays (CLIA) are widely used in clinical laboratories. Some years ago, a CLIA test was developed for the detection of Helicobacter pylori stool samples, known as LIAISON H. SA, but little information on its use has been reported. To evaluate accuracy SA assay diagnosing infection prior to eradication treatment. Diagnostic reliability evaluated 252 untreated consecutive patients with dyspepsia. The gold standard defined concordance rapid urease (RUT),...

10.1136/jim-2015-000004 article EN Journal of Investigative Medicine 2016-01-01

In a previous study, UBiT-100 mg, (Otsuka, Spain), commercial (13)C-urea breath test omitting citric acid pre-treatment, had high rate of false-positive results; however, it is possible that UBiT detected low-density 'occult' infection missed by other routine reference tests. We aimed to validate results in new cohort and rule out the possibility were due an tests.Dyspeptic patients (n = 272) prospectively enrolled was performed, according manufacturer's recommendations. Helicobacter pylori...

10.1177/2050640615572723 article EN other-oa United European Gastroenterology Journal 2015-03-04

Background Helicobacter pylori infection causes long‐term chronic active gastritis, a risk factor for the intestinal and diffuse forms of gastric cancer. Most cancers develop in stepwise progression from gastritis to precursor lesions The early detection cancer improves survival. Studies with recent evidence have proposed circulating‐microRNAs as biomarkers Objective purpose this study was explore circulating‐microRNA profile H. adenocarcinoma. Methods One hundred twenty‐three patients were...

10.1177/2050640618759433 article EN other-oa United European Gastroenterology Journal 2018-02-28

This data article contains related to the research entitled "Variability in microRNA recovery from plasma: Comparison of five commercial kits, doi:10.1016/j.ab.2015.07.018" Brunet-Vega (2015) [1]. PCR efficiency, along with RNA and cDNA quality, are most important factors affecting quality qPCR results. Constant amplification efficiency all compared samples is indispensable when relative quantification used measure changes gene expression. An easy way without need a standard curve, LinRegPCR...

10.1016/j.dib.2015.09.011 article EN cc-by Data in Brief 2015-09-26

Abstract Background Ustekinumab (UST) is a monoclonal antibody that inhibits the p40 subunit of IL-12 and IL-23, approved for treatment Crohn's Disease (CD) Ulcerative Colitis (UC). Its administration intravenous during induction subcutaneous maintenance. Several studies have assessed efficacy reinduction intensification this in patients with loss response. However, there are few evaluating effectiveness UST The aim study to evaluate safety maintenance Inflammatory Bowel (IBD). Methods...

10.1093/ecco-jcc/jjad212.1025 article EN Journal of Crohn s and Colitis 2024-01-01
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