- Inflammatory Bowel Disease
- Microscopic Colitis
- Eosinophilic Esophagitis
- Gastrointestinal Bleeding Diagnosis and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Autoimmune and Inflammatory Disorders
- Gastrointestinal disorders and treatments
- Liver Diseases and Immunity
- Celiac Disease Research and Management
- Diverticular Disease and Complications
- Autoimmune Bullous Skin Diseases
- Diagnosis and treatment of tuberculosis
- Parathyroid Disorders and Treatments
- Mycobacterium research and diagnosis
- Pancreatitis Pathology and Treatment
- Vascular Malformations Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Biosimilars and Bioanalytical Methods
- Esophageal and GI Pathology
- Liver Disease Diagnosis and Treatment
- Tuberculosis Research and Epidemiology
- Healthcare cost, quality, practices
- Helicobacter pylori-related gastroenterology studies
- Intracranial Aneurysms: Treatment and Complications
- Diet and metabolism studies
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas
2022-2025
Corporació Sanitària Parc Taulí
2018-2025
Deleted Institution
2019-2024
Universitat Autònoma de Barcelona
2018-2024
Institute of Research and Innovation Parc Tauli
2018-2024
Instituto de Salud Carlos III
2022-2024
Centro de Investigación Biomédica en Red
2024
Universitat de Barcelona
2024
Institute of Clinical and Experimental Medicine
2021
Pharmacochimie et Pharmacologie pour le Développement
2018
ABSTRACT Objectives: To assess the safety of a polyethylene glycol (PEG) 4000 laxative without additional salts in pediatric patients. Study Design: This was 3‐month multicenter, randomized, double‐blind, double‐dummy, lactulose‐controlled, parallel study enrolling 96 ambulatory constipated children aged 6 months to 3 years, treated daily with 4‐8 g PEG or 3.33 g‐6.66 lactulose. Total protein, albumin, iron, electrolytes, and vitamins B9 (folates), A D (25OHD ) were measured blood before...
Abstract BACKGROUND Rising incidence and prevalence of inflammatory bowel disease (IBD) observed historically in early-industrialized regions now also appear newly-industrialized emerging regions. The epidemiology IBD has been proposed to progress across epidemiologic stages: 1. Emergence (low prevalence); 2. Acceleration Incidence (rapid rising incidence); 3. Compounding Prevalence (stabilizing incidence, rapid prevalence). AIM To gather real-world data on the characterize global each stage...
Abstract Background: Introduction The epidemiologic status of pediatric inflammatory bowel disease (PIBD) has not been widely studied in Western Europe. prevalence and incidence trends the are largely unknown. aim this study is to determine PIBD its mortality rate Catalonia period 2011-2023. Methods: Material methods A longitudinal was performed using population-based data from Catalan Health Surveillance System (CHSS). Data on prevalence, IBD patients under age 18 years were obtained....
Abstract Background The terminal ileum stands out as the most frequently affected segment of gastrointestinal tract in Crohn’s disease (CD). However, ileocolonoscopy (IC) may occasionally fail to fully explore this area. Assessing inflammation activity only lead underestimating overall ileal involvement. Capsule endoscopy (CE) offers a complete examination both entire and proximal segment. Methods This study presents preliminary analysis an ongoing multicenter retrospective conducted at 16...
Patients with colonic inflammatory bowel disease (IBD) have a high risk of colorectal cancer (CRC). Current guidelines recommend endoscopic surveillance, yet epidemiological studies show poor compliance. The aims our study were to analyse adherence its impact on advanced lesions, and factors non-adherence.A retrospective multicentre IBD patients criteria for CRC diagnosed between 2005 2008 followed up 2020, was performed. Following European guidelines, stratified into groups considered when...
Background: The usefulness of thiopurines has been poorly explored in pouchitis and other pouch disorders. Objective: To evaluate the effectiveness safety azathioprine as maintenance therapy inflammatory Design: This was a retrospective multicentre study. Methods: We included patients diagnosed with disorders treated monotherapy. Effectiveness evaluated at 1 year long term based on normalization stool frequency, absence pain, faecal urgency or fistula discharge (clinical remission), any...
Summary Background Ulcerative proctitis (UP) can have a milder, less aggressive course than left‐sided colitis or extensive colitis. Therefore, immunosuppressants tend to be used in patients with this condition. Evidence, however, is scarce because these are excluded from randomised controlled clinical trials. Our aim was describe the characteristics of refractory UP and their disease‐related complications, identify need for immunosuppressive therapies. Methods We identified prospective...
Background Telemonitoring for inflammatory bowel disease (IBD) has not consistently demonstrated superiority over standard care; however, noninferiority may be an acceptable outcome if remote care proves to more efficient. Objective This study aims compare the remission time and quality of life patients with active IBD managed through versus TECCU (Telemonitoring Crohn Disease Ulcerative Colitis) app. Methods A 2-arm, randomized, multicenter trial a design was conducted across 24 hospitals...
Few recent data on the epidemiology of inflammatory bowel disease (IBD) are available, especially in Southern Europe.To evaluate prevalence, incidence and mortality IBD Catalonia during period 2011-2016.Data were obtained from Catalan Health Surveillance System (CHSS). Crude prevalence rates calculated for all population. Trends age-sex-adjusted also estimated, logistic regression was used to calculate adjusted odds ratio (OR). Data Crohn's (CD) ulcerative colitis (UC) analyzed...
Abstract Background Stenosis is one of the most common complications in patients with Crohn’s disease (CD). Endoscopic balloon dilation (EBD) treatment choice for a short stenosis adjacent to anastomosis from previous surgery. Self-expandable metal stents (SEMS) may be suitable option longer stenoses. To date, however, there no scientific evidence as whether endoscopic (EBD/SEMS) or surgical best approach de novo primary stenoses that are less than 10 cm length. Methods/design Exploratory...
Abstract Background There are few data regarding the management on acute severe ulcerative colitis (ASUC) flare in patients with previous anti-TNF exposure. We evaluated medical management, risk of colectomy and factors associated comparing a bionaive cohort. Methods A retrospective multicentric study GETECCU. Patients ASUC episode between 2010-2020 were included two cohorts: bio-exposed (cohort 1) bio-naive 2). other biologics or JAK inhibitors exposure excluded. Steroid response was...
Background: Inflammatory bowel disease (IBD) has a major economic impact on healthcare costs. Objectives: The aim of this study was to evaluate the current expenditure associated with IBD in population-wide Catalonia. Design: Retrospective observational study. Methods: All patients included Catalan Health Surveillance System (CHSS) were considered eligible. CHSS compiles data more than 7 million individuals 2020 (34,823 IBD). Data use resources and its extracted applying International...
Switching from the intravenous to subcutaneous biosimilar infliximab (SC-IFX) has been shown safely maintain clinical remission and increase drug levels in patients with Crohn's disease (CD) ulcerative colitis (UC). The aim of this study was evaluate long-term outcomes after switching IFX (IV-IFX) SC-IFX, concentration thresholds for maintaining other predictors loss response switch.
Background and Aims: Data from clinical trials suggest that biological drugs may improve the outcomes in Crohn’s disease (CD) by reducing need for surgery or hospitalization. The aim of this study is to evaluate time-trends use other treatments CD, its relationship with Catalonia. Materials Methods: All patients CD included Catalan Health Surveillance System (containing data on a population more than 7.5 million) 2011 2017 were identified. exposures different inflammatory bowel retrieved...