A5070976531- Inflammatory Bowel Disease
- Pregnancy and Medication Impact
- Liver Disease Diagnosis and Treatment
- Eosinophilic Esophagitis
- Sepsis Diagnosis and Treatment
- Autoimmune and Inflammatory Disorders
- Microscopic Colitis
- Hemodynamic Monitoring and Therapy
- Hepatitis C virus research
- Helicobacter pylori-related gastroenterology studies
- Gastric Cancer Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Gastrointestinal Bleeding Diagnosis and Treatment
- Gastroesophageal reflux and treatments
- Liver Disease and Transplantation
- Antibiotics Pharmacokinetics and Efficacy
- Respiratory Support and Mechanisms
- Reproductive System and Pregnancy
- Hepatitis B Virus Studies
- Gastrointestinal Tumor Research and Treatment
- Adolescent and Pediatric Healthcare
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Cardiac Arrest and Resuscitation
- Pharmaceutical studies and practices
- Metabolism and Genetic Disorders
Hospital Universitario De Cabueñes
2019-2025
Central University Hospital of Asturias
2015-2019
Hospital de Clínicas "José de San Martín"
1999-2011
University of Buenos Aires
2001-2010
Hospital Universitario Insular de Gran Canaria
2009
Central Bank of Argentina
1987-1992
Missed oesophageal cancer (MEC) at upper gastrointestinal endoscopy (UGE) is poorly documented.The objectives of this study were: (1) to assess the rate, predictors and survival MEC; (2) compare MEC non-MEC tumours.This was a retrospective cohort conducted four tertiary centres. Oesophageal cancers (ECs) diagnosed between 2008 2015 were included. Patients with premalignant condition (Barrett, achalasia), prior diagnosis EC or oesophagogastric junction tumour gastric origin excluded. defined...
Abstract Background Frailty is a dynamic concept that provide more comprehensive assessment of biological reserve and functional status rather than chronological age alone. The aim this study to evaluate the prevalence frailty analyse factors associated with condition in elderly inflammatory bowel disease (IBD) patients. Methods As part Astur-Frailty-IBD (a multicentre prospective IBD patients attended at three hospitals Asturias, Spain), we present baseline data cohort. We recruited all...
Abstract Background The prevalence of older adults with inflammatory bowel diseases (IBD) is increasing. European Crohn's and Colitis Organization recommends that frailty should be considered in management decision-making elderly IBD patients rather than just chronological age. However, there no “gold standard” tool for the assessment IBD. aim this study to assess using 4 scales evaluate agreement between them. Methods Astur-Frailty-IBD study, a multicentre prospective attended at three...
Abstract Background For children born to mothers with inflammatory bowel disease (IBD), the effects of maternal inflammation and exposure biologic drugs during pregnancy may be significant. Elevated systemic markers are linked adverse birth outcomes impaired infant growth. However, specific evaluation within IBD context remains limited, impact drug on early anthropometric is still uncertain. Aim: analyze development malnutrition risk first year life based intrauterine breastfeeding biologics...
Background Descriptive study of physical injuries and implemented organization from a nearby, unwarned university hospital after the July 18, 1994, bombing seven-story Argentine Israeli Mutual Association (AMIA) building in Buenos Aires. Data were obtained medical records. Results A total 86 victims arrived at emergency department, 2 dead on arrival, 41 admitted, 43 with minor assisted allowed to go home. The explosion caused deaths left more than 200 people injured. Mortality rate among...
i] To evaluate the evolution of pregnancies and offspring after inflammatory bowel disease [IBD] surgery during pregnancy; ii] to describe indications, surgical techniques, frequency caesarean section concomitant with surgery.Patients operated on due IBD pregnancy 1998 were included. Participating clinicians asked review their databases identify cases. Data patients' demographics, characteristics, medical treatments, activity, outcomes, surgery, delivery, foetal maternal recorded.In all, 44...
Summary Background Ulcerative proctitis (UP) can have a milder, less aggressive course than left‐sided colitis or extensive colitis. Therefore, immunosuppressants tend to be used in patients with this condition. Evidence, however, is scarce because these are excluded from randomised controlled clinical trials. Our aim was describe the characteristics of refractory UP and their disease‐related complications, identify need for immunosuppressive therapies. Methods We identified prospective...
Abstract Background Helicobacter pylori antibiotic resistance is an increasing problem worldwide. Pylera ® may be option as salvage therapy. Aim To assess the effectiveness, safety, and tolerance of a third‐line in clinical practice. Materials Methods This was multicenter, observational, prospective database study four Spanish hospitals. Consecutive H. ‐infected individuals treated with proton‐pump inhibitor ( PPI ) were invited to participate if they had failed respond...
Crohn's disease is a chronic multifactorial for which therapeutic options have expanded in the last decades. However there are still patients who lack or lose response to current standard treatment strategies. A unicentric, retrospective, study was performed order evaluate clinical and biochemical intravenous ustekinumab manteinance therapy (IVUMT) with refractory CD. We included 12 from our centre started IVUMT between September 2018 November 2021. 75% IV after previous subcutaneous (SC)...
Abstract Background The safety of ustekinumab in pregnant patients with inflammatory bowel disease (IBD) and their offspring has been barely studied. Aims Primary: To know the risk serious adverse events (SAEs) women exposed to during pregnancy offspring. Secondary: assess complications mothers describe patterns use these Methods Patients IBD from DUMBO registry GETECCU were included. is a prospective, observational multicentre registry, which enrols over 5 years 70 centres Spain. was kicked...
Abstract Background Understanding the impact of in utero exposure to biologic medications children is crucial providing recommendations during pregnancy. The effect biologics, particularly non-anti-TNF ones, on children's psychomotor development, has been inadequately studied. Our aim was evaluate biologics development first year life. Methods Data from born IBD patients included DUMBO registry with complete Age and Stages Questionnaire (AQS-3) available up 12 months age were analysed. a...
Abstract Background IBD remission is key for pregnancy outcomes. Previous studies have suggested a disease recurrence risk of approximately 30% in patients at conception, but this could be influenced by control the periconceptional period and discontinuation treatments during pregnancy. Aim To provide updated data on incidence relapse to identify predictive factors relapse. Methods Pregnant with from DUMBO registry were included. prospective, observational, multicentre registry, endorsed...
Abstract Background Crohn's disease (CD) presents differences in genetics, inflammatory components, and microbiota depending on its location. Therapy efficacy may be linked to location, but existing research has yielded conflicting results. This study aims investigate the impact of CD location first-line biologic therapy requirement persistence risk intestinal resections. Methods patients included prospectively maintained ENEIDA registry between January 2005 May 2023 were considered for...
Crohn's disease is a chronic inflammatory disorder which involves mainly the gut. It poses continuous challenge for health care due to lack of effective medical therapies. Given situation this refractory disease, surgery indicated. However, optimal moment perform it stills unknown. Data from 38 patients who underwent elective ileal resection because between years 2019 and 2022 were collected. Early postoperative morbimortality, ileostomy rates, complications rates recurrence retrieved.