A5001713522- Platelet Disorders and Treatments
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pancreatitis Pathology and Treatment
- Blood properties and coagulation
- HIV Research and Treatment
- Immunotherapy and Immune Responses
- Virus-based gene therapy research
- Digestive system and related health
- RNA Interference and Gene Delivery
- Complement system in diseases
- interferon and immune responses
- LGBTQ Health, Identity, and Policy
- Retinoids in leukemia and cellular processes
- Neuroendocrine Tumor Research Advances
- Herpesvirus Infections and Treatments
- Diabetes and associated disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Diet, Metabolism, and Disease
- Extracellular vesicles in disease
- Acute Myeloid Leukemia Research
- Eating Disorders and Behaviors
- Tryptophan and brain disorders
- Blood groups and transfusion
- Cytomegalovirus and herpesvirus research
- Virology and Viral Diseases
Rutgers, The State University of New Jersey
2020-2023
King's College London
2014
Centre International de Recherche en Infectiologie
2014
Université Claude Bernard Lyon 1
2014
École Normale Supérieure de Lyon
2008-2011
Centre Hospitalier Universitaire d'Angers
2001
Inserm
1993-1996
Hôpitaux Universitaires Henri-Mondor
1996
Hôpital Lariboisière
1994
University of Missouri–Kansas City
1987
Interferon induced transmembrane proteins 1, 2 and 3 (IFITMs) belong to a family of highly related antiviral factors that have been shown interfere with large spectrum viruses including Filoviruses, Coronaviruses, Influenza virus, Dengue virus HIV-1. In all these cases, the reported mechanism inhibition indicates pool IFITM present in target cells blocks incoming viral particles endosomal vesicles where they are subsequently degraded.In this study, we describe an additional through which...
Microglia, a type of CNS immune cell, have been shown to contribute ethanol-activated neuronal death the stress regulatory proopiomelanocortin (POMC) neuron-producing β-endorphin peptides in hypothalamus postnatal rat model fetal alcohol spectrum disorders. We determined whether microglial extracellular vesicle exosome is involved ethanol-induced neuron. Extracellular vesicles were prepared from hypothalamic tissues collected rats (both males and females) fed daily with 2.5 mg/kg ethanol or...
ABSTRACT The accessory gene vpr , common to all primate lentiviruses, induces potent G 2 /M arrest in cycling cells. A recent study showed that human immunodeficiency virus type 1 (HIV-1) viral protein R (Vpr) mediates this through activation of the SLX4/MUS81/EME1 exonuclease complex forms part Fanconi anemia DNA repair pathway. To confirm these observations, we have examined phenotypes a panel simian (SIV) Vpr proteins. We show SIV proteins differ their ability promote cell cycle While is...
The purpose of this study was to determine if sexual orientation can be correctly identified under controlled conditions. A series 24 brief videotaped interviews with homosexual and heterosexual men women were presented a sample 143 subject raters divided into four preference gender groups. None the groups able exceed levels correct detection. Approximately 20% total pool did chance levels. There significantly more than in sub-sample represented disproportionately. Although there some...