A5101638856- Cancer, Lipids, and Metabolism
- Biochemical effects in animals
- 3D Printing in Biomedical Research
- Microbial metabolism and enzyme function
- Porphyrin Metabolism and Disorders
- Biosimilars and Bioanalytical Methods
- Genetic Syndromes and Imprinting
- Alzheimer's disease research and treatments
- Aldose Reductase and Taurine
- Epigenetics and DNA Methylation
- Neuroinflammation and Neurodegeneration Mechanisms
- Genetics and Neurodevelopmental Disorders
- Peroxisome Proliferator-Activated Receptors
Singapore Bioimaging Consortium
2019
Agency for Science, Technology and Research
2019
Boston University
1992
Hyperexcitable neurons in brain organoids Individuals with Angelman syndrome experience intellectual disability and seizures throughout their lives. In this condition, ubiquitin-mediated degradation of a key potassium channel is disrupted, allowing for the neuronal excitability network synchronization that leads to seizure. Sun et al. used organoid technology study what happens human mutation ubiquitin ligase implicated syndrome. these vitro models mouse model syndrome, antagonists...