- Advancements in Solid Oxide Fuel Cells
- Catalytic Processes in Materials Science
- Electronic and Structural Properties of Oxides
- Biosensors and Analytical Detection
- Gold and Silver Nanoparticles Synthesis and Applications
- Advanced biosensing and bioanalysis techniques
- NMR spectroscopy and applications
- Nanocluster Synthesis and Applications
- Electrocatalysts for Energy Conversion
- Hydrocarbon exploration and reservoir analysis
- Fuel Cells and Related Materials
- Nanomaterials for catalytic reactions
- Electrochemical Analysis and Applications
- Magnetic and transport properties of perovskites and related materials
- Metal-Organic Frameworks: Synthesis and Applications
- Phase Equilibria and Thermodynamics
- Nanoparticles: synthesis and applications
- Computational Drug Discovery Methods
- Graphene and Nanomaterials Applications
- Viral Infections and Immunology Research
- Spectroscopy and Quantum Chemical Studies
- SARS-CoV-2 detection and testing
- Chemical Looping and Thermochemical Processes
- Quantum Dots Synthesis And Properties
- SARS-CoV-2 and COVID-19 Research
University of St Andrews
2020-2023
Nankai University
2019-2022
State Key Laboratory of Medicinal Chemical Biology
2019-2022
Ninth Hospital of Nanchang
2021
University of Washington
2020
National University of Singapore
2015-2018
Hefei University of Technology
2014-2018
Curtin University
2016
University of Houston
2015-2016
Nanchang Hangkong University
2015
Schematic of study to optimize the SERS enhancement factor a low cost and facile gold nanostar (AuNS)-based paper-SERS substrate through optimizing paper materials, immobilization strategies, acquisition conditions.
Coronavirus 3C-like protease (3CLPro) is a highly conserved cysteine employing catalytic dyad for its functions. 3CLPro essential to the viral life cycle and, therefore, an attractive target developing antiviral agents. However, detailed mechanism of coronavirus remains largely unknown. We took integrated approach X-ray crystallography, mutational studies, enzyme kinetics study, and inhibitors gain insights into mechanism. Such experimental work supplemented by computational including...
Employment of identical oxides for the cathode and anode in a symmetrical solid oxide fuel cell (SSOFC) is beneficial decreasing fabrication costs robust cell. Ce doping on A site SrFeO3 increased structural stability reducing atmosphere, but ceria was found to exsolve from perovskite during cooling process air if level reached 20 atom %. The additional 5 % Ru Sr0.8Ce0.2FeO3 Fe could prevent segregation induce surface decomposition under conditions formation nanoscale SrO, CeO2, Ru0. SSOFC...
The one-pot seedless protocol provides a facile approach in the synthesis of gold nanostars (AuNS) that involves only three reagents, (III) chloride (HAuCl4), silver nitrate (AgNO3) and ascorbic acid (C6H8O6). While studies correlating parameters seed-mediated to surface-enhance Raman scattering (SERS) enhancement is well reported, same understanding limited. Here, we aim elucidate how AuNS from protocol, concentration, surface passivation aggregation level affect colloidal SERS enhancement....
The activity of extracellular protein kinase A (PKA) is known to be a biomarker for cancer. However, conventional PKA assays based on colorimetric, radioactive, and fluorometric techniques suffer from intensive labeling-related preparations, background interference, photobleaching, safety concerns. While surface-enhanced Raman spectroscopy (SERS)-based have been developed various enzymes address these limitations, their use in probing limited due subtle changes the spectrum with...
Enterovirus 71 (EV71) is a major public health threat that requires rapid point-of-care detection. Here, we developed surface-enhanced Raman spectroscopy (SERS)-based scheme utilized protein-induced aggregation of colloidal gold nanostars (AuNS) to rapidly detect EV71 without the need for fabricating solid substrate, labels or complicated sample handling. We used AuNS (hydrodynamic diameter, DH 105.12 ± 1.13 nm) conjugated recombinant scavenger receptor class B, member 2 (SCARB2) protein...
A comparable study of the microstructure and magnetic properties was performed for magnetite films deposited on (100)-oriented MgO SrTiO3 (STO) substrates. The growth strained high quality Fe3O4 confirmed by x-ray diffraction analysis Raman spectroscopy measurements. surface morphology two were found to be obviously different. Moreover, a stripelike domain structure observed in film STO. Substrate-induced strain is believed responsible these observations, which significantly affects...
Targeted covalent inhibitors (TCIs) have attracted growing attention from the pharmaceutical industry in recent decades because they potential advantages terms of efficacy, selectivity, and safety. TCIs recently evolved into a new version with reversibility that can be systematically modulated. This feature may diminish risk haptenization help optimize drug–target residence time as needed. The enteroviral 3C protease (3Cpro) is valuable therapeutic target, but development 3Cpro far...
Studies on the configuration of dye molecules are great importance in revealing origins electronic bands as well understanding their transitions. In this work, we utilized named Nile blue A, which a type oxazine dyes, to study molecular configurations when they transferred from solutions solid surface. The Langmuir-Blodgett (LB) technique was employed construct such an interface where interaction between and supports can be pursued. Hybrid films were prepared via LB depositions, assembled...
Surface chemical and electrochemical techniques were applied to reveal the unfolding of bovine serum albumin (BSA) molecules induced by concentrations in aqueous solution. Real-time surface pressures vs time (π–t) kinetic curves recorded over an subphase (190 mL) spreading BSA solutions different but same amount (8.0 × 10–4 mg) at air/water (A/W) interface. A critical concentration (∼1.0 ppm) was discovered below which pressure declines with is totally solubilized water subphase. Above this...
A novel I<sup>3</sup>O<sup>3</sup> hybrid framework was generated, based on a rare <italic>ths</italic> inorganic subnet of cadmium hydroxide and 3-D organic network linked by tza<sup>2−</sup> ligands Cd(<sc>ii</sc>) centers.
The main barrier to symmetrical solid oxide cells (SSOCs), where the same catalytic materials are used simultaneously as anodes and cathodes, is find a redox-stable catalyst that exhibits superior activities for both fuel oxidation/reduction oxygen reduction/evolution reactions. Here, we report simple strategy by Sc doping La0.6Ca0.4Fe0.8Ni0.2O3−δ (LCFN) with enhanced electrocatalytic activity stability in SSOCs. La0.6Ca0.4Fe0.7Sc0.1Ni0.2O3−δ (LCFSN) has better crystal structural stability,...
In this work, the band-emissions of both magic-sized clusters (MSCs) and nanosized quantum dots (QDs) cadmium arsenide (Cd3As2) are studied versus time during hot-bubbling synthesis. The syntheses performed by introducing ex-situ produced H3As into hot-surfactant solutions dissolved with oleate ligand molecules. It is found that MSCs within 4.0 min because color change solution. However, these not stable, peak photoabsorption shifts from 528 to 540 nm growth time. Across a shallow energy...
Abstract Food grade (K 2 CO 3 wt.%>99.0%, GB/T 25588-2010) potassium carbonate ) has been extracted from low concentration [K + ] solutions of K -Na -H O, which refers to a subsystem brine water in the Lop Nor Lake West China. Procedures isothermal evaporation, crystallization, acidification, filtration, and calcination were employed prepare . This research focuses on phase study metastable equilibria between O KHCO -NaHCO O. The solubility, density, conductivity, pH values determined....
A new type of Nile blue (Nb) derivative molecules terminated with long-chain alkyl (termed as Nb18) has been synthesized from precursors barium stearate and 3-amino-7-(diethylamino)-1,2-benzophenoxazin sulfate. Optical characterizations including UV-Vis absorption, fluorescence emission, excitation spectra the infrared spectroscopy reveal a blueshift in band emission Nb18 compared to Nb molecule, this shift was found be reasoned by incorporation groups replacement SO42−. The amphiphilic were...