A5060339913- Hepatitis C virus research
- Ecology and Vegetation Dynamics Studies
- Wildlife Ecology and Conservation
- Bacterial biofilms and quorum sensing
- Hepatitis B Virus Studies
- Rangeland and Wildlife Management
- Avian ecology and behavior
- Liver Disease Diagnosis and Treatment
- Animal Ecology and Behavior Studies
- Fire effects on ecosystems
- Species Distribution and Climate Change
- Mathematical Biology Tumor Growth
- Algebraic and Geometric Analysis
- Pharmacogenetics and Drug Metabolism
- Black Holes and Theoretical Physics
- Animal Disease Management and Epidemiology
- Viral Infections and Immunology Research
- Geometric and Algebraic Topology
- Hepatitis Viruses Studies and Epidemiology
- Finite Group Theory Research
- Advanced Topics in Algebra
- 3D Printing in Biomedical Research
- Cellular Mechanics and Interactions
- Bacterial Genetics and Biotechnology
- Mathematics Education and Programs
Loughborough University
2015-2024
Berry (United States)
2024
The Task Force for Global Health
2019-2024
Hepatitis B Foundation
2023
National Bureau of Economic Research
2023
Comunidad de Madrid
2022
United States Fish and Wildlife Service
2014-2020
Rocky Mountain Research Station
2001-2020
Rocky Mountain Research (United States)
2001-2020
US Forest Service
2013-2020
Magnesium (Mg) is becoming increasingly popular for orthopaedic implant materials. Its mechanical properties are closer to bone than other materials, allowing more natural healing under stresses experienced during recovery. Being biodegradable, it also eliminates the requirement of further surgery remove hardware. However, Mg rapidly corrodes in clinically relevant aqueous environments, compromising its use. This problem can be addressed by alloying Mg, but challenges remain at optimising...
Hepatitis B (HepB) vaccination is the primary means of preventing infections and complications caused by hepatitis virus (HBV). On February 21, 2018, Advisory Committee on Immunization Practices (ACIP) recommended Heplisav-B (HepB-CpG), a yeast-derived vaccine prepared with novel adjuvant, administered as 2-dose series (0, 1 month) for use in persons aged ≥18 years. The ACIP Vaccines Work Group conducted systematic review evidence, including data from four randomized controlled trials...
A system of nonlinear partial differential equations is proposed as a model for the growth an avascular-tumour spheroid. The assumes continuum cells in two states, living or dead, and, depending on concentration generic nutrient, live may reproduce (expanding tumour) die (causing contraction). These volume changes resulting from cell birth and death generate velocity field within Numerical solutions reveal that after period time variables settle to constant profile propagating at fixed...
Abstract Restoration projects are often developed with little consideration for understanding their effects on wildlife. We contend, however, that monitoring treatment wildlife should be an integral component of the design and execution any management activity, including restoration. Thus, we provide a conceptual framework implementation studies to understand restoration Our underlying premise is effective hinges appropriate study unbiased precise estimates response variables. advocate using...
Nine patients with diabetic neuropathy were treated as outpatients continuous subcutaneous insulin infusion (CSII). Painful symptoms scored on a 10-cm horizontal graphic rating scale; motor conduction velocity (MCV) was measured in the median and peroneal nerves; vibration perception threshold (VPT) recorded great toes. All investigations repeated after 6 wk at completion of 4 mo CSII. Improved control confirmed by significantly lower mean blood glucose levels, M-values, glycosylated...
Summary Chronic hepatitis C virus ( HCV ) infection leads to liver fibrosis, cirrhosis and hepatocellular carcinoma HCC ). The recent Global Burden of Disease project estimated that in 2010 among 170 million people living with chronic , an 483 100 died from ‐related failure or . last two decades has seen progressive improvements treatment the most therapies offering simple, tolerable, short‐duration therapy extremely high efficacy. development public health strategies addressing emerging...
We build on our earlier mathematical model (Ward & King, 1997, IMA J. Appl. Math Med. Biol., 14, 39–69) by incorporating two necrotic depletion mechanisms, which results in a that can predict all the main phases of avascular-tumour growth and heterogeneity. The assumes continuum live cells which, depending concentration generic nutrient, may reproduce or die, generating local volume changes thus producing movement described velocity field. material is viewed as basic cellular (i.e. mix...
Correlations between the home-range size of northern spotted owls (Strix occidentalis caurina) and proportion their range in old-growth forest have been reported, but there are few data on relationship prey. The primary prey wood rats flying squirrels (Glaucomys sabrinus). Wood larger heavier than squirrels, population densities tend to be much greater those squirrels. We present indicating that home ranges smaller where diet consists predominantly it consisting explained significant...
ABSTRACT Forest fire is often considered a primary threat to California spotted owls ( Strix occidentalis ) because has the potential rapidly alter owl habitat. We examined effects of on 7 radiomarked from 4 territories by quantifying use habitat for nesting, roosting, and foraging according severity burn in near 610‐km 2 southern Sierra Nevada, California, USA, years after fire. Three nests were located mixed‐conifer forests, areas moderate‐severity burn, one an area low‐severity nest was...
BackgroundA high prevalence (92.3%) of hepatitis C virus (HCV) co-infection among HIV patients identified during a large outbreak associated with injection oxymorphone in Indiana prompted genetic analysis HCV strains.MethodsMolecular epidemiological HCV-positive samples included genotyping, sampling intra-host HVR1 variants by next-generation sequencing (NGS) and constructing transmission networks using Global Hepatitis Outbreak Surveillance Technology (GHOST).FindingsResults from the 492...
Abstract Background and Aims Suboptimal awareness low rates of hepatitis delta virus (HDV) testing contribute to underdiagnosis gaps in accurate estimates U.S. HDV prevalence. We aim provide an updated assessment prevalence the using a comprehensive literature review meta‐analysis approach. Methods A articles reporting HBsAg seroprevalence anti‐HDV was conducted calculate country‐specific pooled CHB meta‐analyses. Country‐specific rate were combined with number foreign‐born (FB) persons 2022...
We investigated ways in which undergraduates use optional learning resources a typical blended environment. Specifically, we recorded how often students attended live face-to-face lectures, accessed online and visited mathematics support centre during multivariate calculus course. Four distinct study strategies emerged, but surprisingly none involved making heavy of more than one resource. In contrast with some earlier research, the general strategy student adopted was related to their...
The regulation of density‐dependent behaviour by means quorum sensing is widespread in bacteria, the relevant phenomena including bioluminescence and population expansion swarming, as well virulence. process regulated production monitoring certain molecules (referred to QSMs); on reaching an apparent threshold concentration QSMs (reflecting high bacterial density) colony concert ‘switches on’ trait. In this paper a mathematical model which describes growth mixed system proposed studied. We...
We tested three predictions of a hypothesis that states Northern Spotted Owls (Strix occidentalis caurina) select habitat according to the distribution their primary prey. Our were should (1) larger (> 100 g) species among assemblage available prey, (2) habitats large and (3) owl's reproductive success be influenced by availability also evaluated potential energetic value several prey species. found (n = 11 pairs 1 single male) in northwestern California differentially selected dusky-footed...
ABSTRACT The new plankton-counting cell is an annular groove machined in a circular plate of lucite. mounted on turntable and driven at rate about one revolution six minutes. Counting done by observation the rotating sample as it moves through field microscope. This apparatus provides convenience ‘trough flow systems currently used has advantage being more compact unit.