A5087737207- Invertebrate Immune Response Mechanisms
- Parasites and Host Interactions
- Insect symbiosis and bacterial influences
- Parasite Biology and Host Interactions
- Antimicrobial Peptides and Activities
- Mosquito-borne diseases and control
- Aquaculture disease management and microbiota
- Macrophage Migration Inhibitory Factor
- Immune Response and Inflammation
- Complement system in diseases
- Helminth infection and control
- Plant Pathogenic Bacteria Studies
- Reproductive System and Pregnancy
- Malaria Research and Control
- Antimicrobial Resistance in Staphylococcus
Centre National de la Recherche Scientifique
2012-2017
Institut Sophia Agrobiotech
2012-2017
Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement
2017
Institut de Biologie Moléculaire des Plantes
2015
Institut de Biologie Moléculaire et Cellulaire
2013-2015
Centro Internacional de Entrenamiento e Investigaciones Medicas
2010-2013
Université Côte d'Azur
2013
Modèles Insectes de l'Immunité Innée
2012
Abstract Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni . With World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize genome glabrata, lophotrochozoan protostome, and provide timely important information biology. We describe aspects phero-perception, stress responses, immune function regulation gene expression that support...
Aedes aegypti is the principal vector of Dengue viruses worldwide. We identified field collected insects with differential susceptibility to Dengue-2 virus (DENv-2) and used isofemale selection establish susceptible refractory strains based on midgut infection barriers. Previous experiments had higher expression apoptosis-related genes in strain. To identify potential molecular mechanisms associated DENv susceptibility, we evaluated Caspase-16, Aedronc, Aedredd, Inhibitor apoptosis (AeIAP1)...
Vertebrate females transfer antibodies via the placenta, colostrum and milk or egg yolk to protect their immunologically immature offspring against pathogens. This evolutionarily important of immunity is poorly documented in invertebrates basic questions remain regarding nature extent parental protection offspring. In this study, we show that a lipopolysaccharide binding protein/bactericidal permeability increasing protein family member from invertebrate Biomphalaria glabrata (BgLBP/BPI1)...
Our present understanding of the functioning and evolutionary history invertebrate innate immunity derives mostly from studies on a few model species belonging to ecdysozoa. In particular, characterization signaling pathways dedicated specific responses towards fungi Gram-positive or Gram-negative bacteria in Drosophila melanogaster challenged our original view non-specific invertebrates. However, much remains be elucidated lophotrochozoan species. To investigate global specificity immune...
Suppressive subtractive hybridization was used to evaluate the differential expression of midgut genes feral populations Aedes aegypti (Diptera: Culicidae) from Colombia that are naturally refractory or susceptible Dengue-2 virus infection. A total 165 differentially expressed sequence tags (ESTs) were identified in subtracted libraries. The analysis showed a higher number Ae. individuals than mosquitoes. functional annotation ESTs revealed broad response library included immune molecules,...
Abstract The vector competence (VC) of Aedes aegypti (Linnaeus) (Diptera: Culicidae) varies geographically and is affected by both genetic environmental factors. Understanding the molecular mechanisms that influence VC may help develop novel control strategies. selection susceptible refractory strains first step in this process. We collected immature A. field established were to Dengue-2 virus isofamily through several generations. Infection was detected immunofluorescence head or midgut...