A5044107632- Parasites and Host Interactions
- Parasite Biology and Host Interactions
- Helminth infection and control
- Research on Leishmaniasis Studies
- Trace Elements in Health
- Myxozoan Parasites in Aquatic Species
- Echinoderm biology and ecology
- Antimicrobial Peptides and Activities
- Marine Bivalve and Aquaculture Studies
- RNA Interference and Gene Delivery
- Environmental DNA in Biodiversity Studies
- Aquatic Invertebrate Ecology and Behavior
- Rabbits: Nutrition, Reproduction, Health
- Cephalopods and Marine Biology
- Animal Genetics and Reproduction
- Malaria Research and Control
- Toxin Mechanisms and Immunotoxins
- CRISPR and Genetic Engineering
- Invertebrate Immune Response Mechanisms
- Fish Ecology and Management Studies
- Aquaculture disease management and microbiota
Government of Alberta
2021
University of Alberta
2013-2020
Abstract Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni . With World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize genome glabrata, lophotrochozoan protostome, and provide timely important information biology. We describe aspects phero-perception, stress responses, immune function regulation gene expression that support...
Schistosomiasis, a devastating disease caused by parasitic flatworms of the genus Schistosoma, affects over 260 million people worldwide especially in tropical and sub-tropical regions. Schistosomes must undergo their larval development within specific species snail intermediate hosts, trait that is shared among almost all digenean trematodes. This unique long-standing host-parasite relationship presents an opportunity to study both importance conserved immunological features novel roles, as...
Digenean trematodes are a large, complex group of parasitic flatworms that infect an incredible diversity organisms, including humans. Larval development most digeneans takes place within snail (Gastropoda). Compatibility between snails and is often very specific, such suitable hosts define the geographical ranges diseases caused by these worms. The immune cells (hemocytes) sentinels act as crucial barrier to infection larval digeneans. Hemocytes coordinate robust specific immunological...
Immune factors in snails of the genus Biomphalaria are critical for combating Schistosoma mansoni, predominant cause human intestinal schistosomiasis. Independently, many these play an important role in, but do not fully define, compatibility between model snail B. glabrata, and S. mansoni. Here, we demonstrate association four previously characterized humoral immune molecules; BgFREP3, BgTEP1, BgFREP2 Biomphalysin. We also identify unique determinants plasma mansoni-resistant glabrata that...
Metalloproteases (MPs) have demonstrated roles in immune modulation. In some cases, these enzymes are produced by parasites to influence host responses such that parasite infection is facilitated. One of the best examples parasite-mediated modulation matrix metalloprotease (MMP) leishmanolysin (Gp63), which species genus Leishmania evade killing macrophages. Leishmanolysin-like proteins appear be quite common many invertebrates, however our understanding functions non-leishmania limited....
We provide the first documented case of whirling disease (WD) impacts to wild, self-sustaining rainbow trout (RNTR, Oncorynchus mykiss) populations in Canada. Myxobolus cerebralis (Mc), causative agent WD, was confirmed Alberta 2016. However, evidence local fish unknown. Using a weight-of-evidence approach, we examined multiple parasite life cycle stages Crowsnest River, Alberta. Percentage infected Tubifex tubifex worms actively shedding triactinomyxons (TAMs) exceeded known thresholds Mc...
Gastropod molluscs, which have co-evolved with parasitic digenean trematodes for millions of years, utilize circulating heamocytes as the primary method containing and killing these invading parasites. In order to do so, they must generate suitable amounts haemocytes that are properly armed kill worms. One by required initiate appropriate cell mediated immune response is via production post-translational processing granulins. Granulins an evolutionarily conserved family growth factors...
DAO Diseases of Aquatic Organisms Contact the journal Facebook Twitter RSS Mailing List Subscribe to our mailing list via Mailchimp HomeLatest VolumeAbout JournalEditorsSpecials 145:119-137 (2021) - DOI: https://doi.org/10.3354/dao03608 qPCR-based environmental monitoring Myxobolus cerebralis and phylogenetic analysis its tubificid hosts in Alberta, Canada Danielle E. Barry1, Marie Veillard2,3, Clayton T. James2,3, Leah Brummelhuis1, Emmanuel A. Pila2, Alyssa Turnbull1, Arnika Oddy-van...
The reservoir status of rabbits for a strain Ehrlichia ruminantium was investigated using six experimental and four controlled rabbits. Each the animals intraperitoneally inoculated with 1.5 ml infective blood from febrile goat. effect parasite on body weight, packed cell volume, total protein daily morning rectal temperature monitored. Analysis variance (ANOVA) revealed significant differences (p < 0.05) in between However, LSD test showed no samples. Following apparent non-reaction to...
Abstract Immune factors in snails of the genus Biomphalaria are critical for combating Schistosoma mansoni , predominant cause human intestinal schistosomiasis. Independently, many these known to play an important role in, but not fully define, compatibility between model snail B. glabrata, and S. . Here, we demonstrate association four, previously characterized humoral immune molecules; Bg FREP3, TEP1, FREP2 Biomphalysin. We also identify unique determinants plasma -resistant glabrata that...