Lakshmi Alagappan

ORCID: 0000-0003-0582-1513
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About
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Research Areas
  • Electric Power System Optimization
  • Spectroscopy and Chemometric Analyses
  • Spectroscopy Techniques in Biomedical and Chemical Research
  • Integrated Energy Systems Optimization
  • Heme Oxygenase-1 and Carbon Monoxide
  • Energy Efficiency and Management
  • Smart Grid Energy Management
  • Eicosanoids and Hypertension Pharmacology
  • Advanced Chemical Sensor Technologies
  • Energy Load and Power Forecasting
  • Alcohol Consumption and Health Effects

Wilmar International (Singapore)
2023

National University of Singapore
2023

Environmental Energy & Engineering
2011-2016

Long Island Jewish Medical Center
2010

North Shore University Hospital
2010

Mesangial cell (MC) proliferation is a hallmark of many progressive renal diseases. Heme oxygenase-1 (HO-1) has been shown to have an anti-proliferative effect on vascular smooth muscle cells. In the present study, we evaluated role HO-1 MC and involved molecular mechanism. Both epidermal growth factor (EGF) hepatocyte (HGF) not only enhanced mesangial expression but also stimulated MCs. Interestingly, inhibition induction (by zinc protoporphyrin, ZnP) was associated with accelerated...

10.3109/08860220903491240 article EN Renal Failure 2010-03-01

Classification of NIR spectra is a common problem in chemometrics. An ideal classification model should not only classify into the known defined classes but also detect that do belong to any classes. On top this, perform well on with unwanted source variation (batch effects) obtained under different conditions. more distinct (different edible oils) relatively easier than less (purities oils). It crucial eliminate batch effects while keeping signal separates effectively. conditions often...

10.1016/j.chemolab.2023.104977 article EN cc-by-nc-nd Chemometrics and Intelligent Laboratory Systems 2023-08-31
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