A5052918100- Tuberculosis Research and Epidemiology
- Global Maternal and Child Health
- Vaccine Coverage and Hesitancy
- HIV/AIDS Research and Interventions
- Pneumonia and Respiratory Infections
- Viral Infections and Outbreaks Research
- Healthcare Systems and Reforms
- SARS-CoV-2 and COVID-19 Research
- Immune responses and vaccinations
- Adolescent Sexual and Reproductive Health
- SARS-CoV-2 detection and testing
- Pneumocystis jirovecii pneumonia detection and treatment
- HIV, Drug Use, Sexual Risk
- COVID-19 epidemiological studies
- Hepatitis B Virus Studies
- Medication Adherence and Compliance
- COVID-19 diagnosis using AI
- Non-Invasive Vital Sign Monitoring
- Global Health and Epidemiology
- Virology and Viral Diseases
- HIV/AIDS drug development and treatment
- Malaria Research and Control
- Mycobacterium research and diagnosis
- Pharmaceutical studies and practices
- Poverty, Education, and Child Welfare
Ifakara Health Institute
2012-2025
Kilimanjaro Christian Medical Centre
2023
Nelson Mandela African Institution of Science and Technology
2023
A critical impediment to efficient outbreak response is the availability of timely and complete data on cases their linkage care. To inform solutions this issue, study investigated utility self-testers reporting coronavirus disease 2019 results using a mobile health platform. Our has demonstrated that platform feasible; it achieved 74.5% rate, indicating strong likelihood entry into unstructured supplementary service Support from community workers (CHWs) healthcare professionals,...
The relationship between education and cardiovascular health (CVH) metrics in low- middle-income countries (LMICs) remains unclear. This study explores the associations ideal score (CVHS), as well seven CVH metrics. cross-sectional extracted data from STEPwise approach to surveillance surveys 36 LMICs 2010 2020. We assessed CVHS using sum defined by American Heart Association: (1) ≥ 150 min/week of moderate, or 75 vigorous activity, an equivalent combination; (2) BMI < 25 kg/m2 for...
Background Non-adherence to tuberculosis (TB) treatment is the leading contributor selection of drug-resistant strains Mycobacterium and subsequent failure. Tanzania introduced a TB Patient Centred Treatment (PCT) approach which gives new patients choice between home-based supervised by supporter their own choice, health facility–based observed medical professional. The aim this study was assess extent determinants adherence anti-TB therapy in opting for under novel PCT approach. Methods In...
With a view to improve neonatal survival, data on birth outcomes are critical for planning maternal and child health care services. We present information survival from Ifakara Health Demographic Surveillance System (HDSS) in Tanzania, regarding the influence of mother's age other related factors first second births. The study conducted analysis using longitudinal demographic collected HDSS parts Kilombero Ulanga districts Morogoro region. included live births that occurred within six years...
BackgroundQuality of care is consistently shown to be inadequate in health-care settings many low-income and middle-income countries, including private facilities, which are rapidly growing number but often do not have effective quality stewardship mechanisms. The SafeCare programme aims address this gap care, using a standards-based approach adapted low-resource settings, involving assessments, mentoring, training, access loans, improve clinical facility business performance. We assessed...
It is estimated that 287,000 women worldwide die annually from pregnancy and childbirth-related conditions, 6.9 million under-five children each year, of which about 3 are newborns. Most these deaths occur in sub-Saharan Africa. The maternal health situation Tanzania mainland Zanzibar similar to other countries. This study assessed the availability, accessibility quality emergency obstetric care services essential resources available for child Zanzibar. From October November 2012, a...
Abstract Background Directly observed therapy (DOT) remains the cornerstone of global tuberculosis (TB) control strategy. Tanzania, one 22 high-burden countries regarding TB, changed first-line treatment regimen to contain rifampicin-containing fixed-dose combination for full 6 months treatment. As daily health facility-based DOT this long period is not feasible patient, nor system, Tanzania introduced patient centred (PCT). PCT allows patients choose at a facility or their home by supporter...
In April 2018, Tanzania introduced the human papillomavirus (HPV) vaccine nationally to 14-year-old girls, utilizing routine delivery strategies (i.e. vaccinating girls at health facilities and community outreach, including schools). We sought assess awareness, feasibility, acceptability of HPV vaccination program among workers community-level stakeholders. conducted cross-sectional in-person surveys workers, school personnel, leaders, council leaders in 18 areas across six regions...
Background: The incidence of tuberculosis among HIV-infected populations with high CD4 count in burden countries has not been well studied.Objective: To assess the TB adults and its associated risk factors.Method: A cohort study retrospective review medical records prospective follow-up adult participants attending CTC who were 18-55 years old, had more than 250 cells/mm3 period 2008-2010 on ART at enrolment. Cox proportional hazard regression was used to explore predictors incident...
Decentralization of Directly Observed Treatment (DOT) for tuberculosis (TB) to the community (home-based DOT) has improved coverage TB treatment and reduced burden health care facilities (facility-based DOT). We aimed compare outcomes in home-based facility-based DOT under programmatic conditions an urban setting with a high burden.A retrospective analysis cohort adult patients (≥15 years) routinely notified between 2010 2013 two representative sub-districts Temeke district, Dar es Salaam,...
Patient Centred Tuberculosis Treatment (PCT) is a promising treatment delivery strategy for Mycobacterium tuberculosis (TB). It aims to improve adherence by giving patients the choice of having drug intake supervised at health facility medical professional or home supporter their choice. A cross-sectional survey was undertaken in three districts Tanzania during October 2007, one year after PCT rolled out nationally. Semi-structured questionnaires were used assess whether key elements...
Immunization has saved millions of lives globally from vaccine-preventable diseases. Childhood immunization is an effective public health strategy for decreasing morbidity and mortality among children in developing countries. Tanzania one the highest rates coverage routine child sub-Saharan African However, obstacles to universal still exist, particularly rural areas country. Assessing essential inform vaccine policies program implementation. This study aimed assess status factors associated...
Arusha, Mwanza, Mufindi and Kilosa in Tanzania.To assess the test characteristics of three indirect adherence measures against a gold standard direct measurements drug intake for use resource-constrained setting.We assessed sensitivity, specificity, positive predictive value (PPV) negative (NPV), diagnostic odds ratio (dORs) measurement tools urine using IsoScreen assay.The single question missed doses last 2 days had highest dOR (40.3) compared to Morisky medication scale (MMAS, 2.5) pill...
New strategies are needed to improve HIV testing rates in Tanzania, particularly among adult men. We sought investigate if oral self-testing would increase uptake Tanzanian rural community homes. The study design was a prospective community-randomized pilot study, two matched villages with similar characteristics (intervention and control villages) Before data collection, we trained village health workers research assistants for one week. recruited male female adults from 50 representative...
Although studies on COVID-19 vaccine hesitancy are being undertaken widely worldwide, there is limited evidence in Tanzania. This study aims to assess the sociodemographic factors associated with and reasons given by unvaccinated participants. We conducted a mixed-method cross-sectional two components-health facilities communities-between March September 2022. A structured questionnaire in-depth interviews were used collect quantitative qualitative data, respectively. total of 1,508...
Abstract A pilot implementation of the rapid diagnostic test program was performed to collect evidence feasibility, acceptability, and uptake COVID-19 AgRDT in Tanzania. We conducted a prospective cross-sectional study community provide quantitative details antigen (AgRDT) This undertaken between March 2022 September 2022. The implemented by distributing offering kits people suspected having Dar es Salaam through health workers. total 1039 participants consented participate survey. All...
The rapid diagnosis of coronavirus disease 2019 (COVID-19) is critical for comprehensive public health response strategies, and self-testing with antigen diagnostic tests (Ag-RDTs) presents opportunities to test in hard-to-reach communities. Therefore, we evaluated the acceptability, feasibility, uptake Ag-RDT at community level Tanzania. From June October 2022, symptomatic individuals or those recent contact a known suspected COVID-19 patient were offered assisted testing within mining...
Prevention of unplanned pregnancies through modern contraceptives among HIV-positive women is one the essential strategies for reducing mother-to-child transmission HIV. Family planning and HIV services integration a national strategy designed to scale-up women. This study aims evaluate success service by comparing prevalence contraceptive use receiving ART within integrated those not on (HIV-negative unaware their status).We used data from Tanzania impact survey (THIS) 2016/17. THIS...
Urinary schistosomiasis is more prevalent in schoolaged children than adults (Hussein et al., 1996).Thus interventions aimed at school-aged focusing on delivery through schools are strongly encouraged (WHO, 1993).School-based programmes provide an infrastructure for delivering treatment against geohelminths and (PCD, 1999).Such have been shown to improve health well-being of schoolchildren Tanzania (Guyatt 2001), the acceptability such among teachers parents acceptably high (PCD 2001).Kilosa...