Sebile Çomçalı

ORCID: 0000-0003-0596-1452
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About
Contact & Profiles
Research Areas
  • Glaucoma and retinal disorders
  • Retinal Diseases and Treatments
  • Retinal Imaging and Analysis
  • Retinal and Optic Conditions
  • Ocular Surface and Contact Lens
  • Intraocular Surgery and Lenses
  • Corneal surgery and disorders
  • Digital Imaging in Medicine
  • Phytochemistry and Biological Activities
  • Connexins and lens biology
  • Ocular and Laser Science Research
  • Corneal Surgery and Treatments
  • Blood groups and transfusion
  • Optical Coherence Tomography Applications
  • Injury Epidemiology and Prevention
  • Drug-Induced Ocular Toxicity
  • Systemic Lupus Erythematosus Research
  • Vascular Tumors and Angiosarcomas
  • Vascular Malformations Diagnosis and Treatment
  • Retinal and Macular Surgery
  • Dermatoglyphics and Human Traits
  • Retinoids in leukemia and cellular processes
  • Ocular Oncology and Treatments
  • Preterm Birth and Chorioamnionitis
  • Renal cell carcinoma treatment

Bilkent University
2023-2025

Ankara Bilkent City Hospital
2023-2025

Memorial Ankara Hospital
2022-2023

City Hospital
2022-2023

Sağlık Bilimleri Üniversitesi
2020-2021

Ankara Mevki Asker Hastanesi
2021

Ankara Numune Eğitim ve Araştırma Hastanesi
2020

Sivas State Hospital
2014-2015

Background: Axitinib is a selective inhibitor of vascular endothelial growth factor receptors and used in the treatment many malignancies. Herein, we reported rare case with axitinib-induced retinal changesand associated toxicity. Case Presentation: A forty-five-year-old female presented blurred vision who had been taking 7 mg bid for 5 months. Initial Best Corrected Visual Acuity (BCVA) was 20/32 at right counting fingers left eye. Funduscopic examination revealed bilaterally widespread...

10.2174/0115734056328844240821172430 article EN cc-by Current Medical Imaging Formerly Current Medical Imaging Reviews 2025-02-28

Abstract Purpose To investigate the prevalence of exfoliation syndrome and its relationship with ocular cardiovascular diseases in Central Anatolia region Turkey. Methods This cross‐sectional population‐based study was conducted at Sivas Province among population aged 40 years over. The diagnosis XFS made when exfoliative material found on anterior lens capsule or iris slit‐lamp examination. subjects were divided into an group a non‐ according to presence material, groups compared for...

10.1111/aos.12885 article EN Acta Ophthalmologica 2015-10-28

Capsulorhexis is the most important step in intumescent cataract due to high risk of radial extension capsular tear during surgery. The aim this study present modified two-stage capsulorhexis technique for cataract.The was used study. A small size approximately 1.5-2 mm diameter created first stage. Liquefied cortex aspirated with a 25 G cannula equalize anterior chamber pressure and intracapsular after capsulorhexis. In second stage, 5-6 performed safe phacoemulsification.A total 73...

10.1186/s12886-023-02895-4 article EN cc-by BMC Ophthalmology 2023-04-04

Aim. The aim of this study was to investigate the frequency exfoliation syndrome in Central Anatolia region Turkey and evaluate its relationship with cardiovascular ocular diseases. Methods. Patients over age 45 years who presented clinic were included study. All cases underwent a comprehensive ophthalmology examination. Exfoliation diagnosed presence exfoliative material on lens anterior capsule or iris slit lamp patients divided into two groups as group nonexfoliation according material....

10.1155/2014/139826 article EN cc-by Journal of Ophthalmology 2014-01-01

To evaluate the optical coherence tomography angiography (OCT-A) findings in patients with systemic lupus erythematosus (SLE). Twenty-eight eyes of 28 SLE and 27 age sex matched healthy controls were enrolled this cross-sectional study. The vessel densities macula optic disc evaluated using OCT-A (Optovue, Inc., Freemont, CA). Foveal retinal thickness, vascular density superficial capillary plexus (SCP), deep plexus, choriocapillaris, foveal avascular zone (FAZ), acircularity index, (FD),...

10.1097/md.0000000000035835 article EN cc-by-nc Medicine 2023-10-27

Examination of corneal densitometry measurements using the Pentacam Scheimpflug imaging system in cases pseudoexfoliative glaucoma (PEXG) and ocular hypertension (OHT). The study included 50 eyes 29 PEXG patients, 25 16 OHT 76 38 healthy control subjects followed clinic. Corneal values all were measured (Pentacam, Oculus, Germany). was assessed based on 4 concentric radial zones (0-2 mm, 2-6 6-10 10-12 mm) depths (anterior, central, posterior, total) within system. results statistically...

10.1016/j.pdpdt.2024.103988 article EN cc-by-nc-nd Photodiagnosis and Photodynamic Therapy 2024-02-16

Background:: Immune thrombocytopenic purpura (ITP) is a rare auto-antibody mediated disease of isolated thrombocytopenia (<100,000/μL) with normal haemoglobin levels and leukocyte counts. Only small number ITP cases have been reported accompanying ophthalmological findings. Herein, we report an case demonstrative retinal haemorrhages. Case Presentation:: A fifty-five-year-old woman known history type 2 diabetes mellitus was referred to our clinic blurred vision. After detailed anamnesis...

10.2174/0115734056270927231123105203 article EN cc-by Current Medical Imaging Formerly Current Medical Imaging Reviews 2024-02-13

Introduction Iodine deficiency is a leading cause of preventable physical and mental retardation. Potassium iodate used for iodine supplementation to prevent deficiency. We herein report case toxic retinopathy following intentional ingestion potassium iodine. Case Presentation A 41-year-old male presented with 5-day history blurred vision in both eyes. His visual acuity (VA) was hand motion his pupillary reactions were sluggish bilaterally. The fundus examination revealed bilaterally diffuse...

10.1177/1120672120926862 article EN European Journal of Ophthalmology 2020-05-26

Aim: The central corneal thickness (CCT) of healthy individuals was measured with an ultrasonic pachymeter (UP) and the Scheimpflug imaging system (SIS) results were compared to evaluate agreement between two methods in this study. Materials Methods: 61 subjects who had no ocular pathology or systemic disease except blepharitis included CCT measurements all performed UP (Sonomed 300P Pacscan) SIS (Nidek Optical biometer AL-Scan) devices compared. t test Bland-Altman plot used as statistical...

10.9734/bjmmr/2015/17579 article EN British Journal of Medicine and Medical Research 2015-01-10

Purpose: To evaluate Optical Coherence Tomography Angiography (OCT-A) findings in patients with Ocular hypertension and compare them healthy controls.Methods: Thirty-four ocular 22 individuals were included the study. Foveal thickness, retinal vascular density superficial deep capillary plexus choriocapillaris, foveal avascular zone , acircularity index vessel density, non-flow area, all densities peripapillary area disc automatically measured using Angiovue software of OCT-A compared...

10.2139/ssrn.4343416 article EN 2023-01-01

Abstract Background: Several structural, vascular density and perfusion studies were conducted in type 1 2 diabetes, even the absence of retinopathy. The current study is first to compare macular vessel densities (VD) by optical coherence tomography angiography (OCTA) between maturity onset diabetes young (MODY) patients healthy controls. Methods : VD superficial, deep retina, choriocapillaris, central thickness (CMT), foveal avascular zone area (FAZ), FAZ perimetry, total retina at 300µm...

10.21203/rs.3.rs-2495369/v1 preprint EN cc-by Research Square (Research Square) 2023-02-15

Abstract Background: Axitinib is a selective inhibitor of vascular endothelial growth factor receptors. Case presentation: A forty-five years old female presented with blurred vision who had been taking 7 mg bid for 5 months. Initial best corrected visual acuity (BCVA) was 20/32 at the right and counting fingers left eye. Funduscopic examination revealed bilaterally widespread intraretinal hemorrhages, cotton-wool spots, hard exudates star-like appearance macula. The optical coherence...

10.21203/rs.3.rs-3256701/v1 preprint EN cc-by Research Square (Research Square) 2023-08-21

Amaç
 Sağlık çalışanlarında FFP2/N95 yüz maskesinin oksijen
 satürasyonu (SpO2), maküla ve optik disk damar
 dansitesi üzerindeki etkisinin koherens tomografi
 anjiyografi (OKTA) ile değerlendirilmesi amaçlanmıştır.
 Gereç Yöntem
 Çalışmaya 19 gönüllü sağlık çalışanının 38 gözü dahil
 edilmiştir. Tam oftalmolojik muayeneleri yapılmıştır.
 N95 maske takılmasından hemen önce 4 saat sürekli
 kullanımından sonra oksijen saturasyonunu
...

10.17343/sdutfd.1346713 article TR cc-by-nc-nd SDÜ Tıp Fakültesi Dergisi 2023-09-19

Abstract Purpose To evaluate Optical Coherence Tomography Angiography (OCT-A) findings in patients with Ocular Hypertension (OHT) and compare them healthy individuals. Material Methods Thirty-four ocular hypertension 22 individuals were included the study. Foveal thickness, retinal vascular density superficial deep capillary plexus choriocapillaris, foveal avascular zone (FAZ), acircularity index (AI), vessel (FD), non-flow area, all densities peripapillary area disc automatically measured...

10.21203/rs.3.rs-2007637/v1 preprint EN cc-by Research Square (Research Square) 2022-09-08

Amaç: Bu çalışmanın amacı iki farklı optik koherens tomografi (OKT) anjiografi cihazından elde edilen verileri karşılaştırmaktır.

10.46332/aemj.847635 article TR cc-by-nc Ahi Evran Medical Journal 2021-01-17

Amaç: Neovasküler Glokomlu olgularda intravitreal bevacizumabın etkinliğini ve güvenilirliğini değerlendirmektir. Gereç Yöntemler: Kliniğimizde neovasküler glokom tanısıyla bevacizumab uygulanan en az 4 ay takip edilen 20 hastanın 23 gözü retrospektif olarak değerlendirildi. Enjeksiyon öncesinde sonrasında ön segment renkli resim floresein anjiyografi çekilerek karşılaştırıldı. maksimum antiglokomatöz medikal tedavi verilen hastalara 1,25 mg / 0,05 ml uygulandı. Hastalar enjeksiyon sonrası...

10.17517/ksutfd.852577 article TR cc-by-nc-nd Kahramanmaraş Sütçü İmam Üniversitesi Tıp Fakültesi Dergisi 2021-02-09

Randomised-controlled clinical trials (the ANCHOR and MARINA) examined the intravitreal anti-vascular endothelial growth factor (anti-VEGF) efficacy for eyes having fluorescein angiographic classic occult (OCC) neovascular lesions. No significant difference in treatment response between lesion types was observed. Fundus angiography optical coherence tomography (OCT) are complementary devices that provide information about age-related macular degeneration (n-AMD). The aim of this...

10.1177/25158414211005305 article EN cc-by-nc Therapeutic Advances in Ophthalmology 2021-01-01
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