A5083943458- Wound Healing and Treatments
- Diabetic Foot Ulcer Assessment and Management
- Essential Oils and Antimicrobial Activity
- Phytochemistry and Biological Activities
- Traditional Chinese Medicine Analysis
- Bee Products Chemical Analysis
- Retinal Diseases and Treatments
- Genital Health and Disease
- Glaucoma and retinal disorders
- Pressure Ulcer Prevention and Management
- Biological Activity of Diterpenoids and Biflavonoids
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Genomics, phytochemicals, and oxidative stress
- Aluminum toxicity and tolerance in plants and animals
- Advanced Glycation End Products research
- Lichen and fungal ecology
- Cancer Mechanisms and Therapy
- Phytoestrogen effects and research
- Electromagnetic Fields and Biological Effects
- Garlic and Onion Studies
- Tuberculosis Research and Epidemiology
- Pharmacological Effects of Medicinal Plants
- Liver physiology and pathology
- Plant Toxicity and Pharmacological Properties
Karadeniz Technical University
2024
Adıyaman University
2010-2023
State Planning Organization
2020
Sivas State Hospital
2015
Ahi Evran University
2009-2012
Diabetic patients suffer from persistent and non-healing wounds. Salvia species are traditionally used for the treatment of wounds colds. The aims present study were to evaluate in vivo wound healing potential, vitro antimicrobial antioxidant activities, total phenolic flavonoid contents aerial parts two endemic taxa, kronenburgii Rech. f. (SK) euphratica Montbret, Aucher & var. (SE). Two different concentrations (0.5% 1% (w/w)) ethanol extracts investigated incision excision models on...
Luteolin, which is structurally classified under the flavonoids, naturally distributed abundant among medicinal plants, vegetables and fruits.The wound healing effects of Luteolin ointments were evaluated for incision excision models on non-diabetic Streptozotocin induced diabetic rats by using macroscopical, biomechanical, biochemical histopathological methods.Two different concentrations (0.5 % 1 (w/w)) ointment prepared with mixture glycol stearate:propylene glycol:liquid paraffin (3:6:1)...
SUMMARY OBJECTIVE: Asporin is secreted by theca cells in the mouse ovaries and an effective marker at gonadotropin-independent stage secondary follicle development. It has inhibitory effect on transforming growth factor beta bone morphogenic proteins, which are involved androgenesis process. Our aim was to compare serum asporin levels of polycystic ovary syndrome control groups examine relationship between hyperandrogenism. METHODS: A total 60 patients, i.e., 30 group controls, were included...
The genus Salvia L. (Lamiaceae) has been traditionally used for the treatment of various illnesses since ancient times. hispanica L., commonly known as Chia, is an annual herbaceous plant which was one most significant crops pre-Columbian civilizations (Aztec and Maya) in America. Nutritional potential beneficial effects Chia seeds on human health have previously reported. Therefore, this study aims to investigate anti(myco)bacterial, antifungal, antiproliferative activities seeds. Ethanol...
Abstract Purpose To investigate the prevalence of exfoliation syndrome and its relationship with ocular cardiovascular diseases in Central Anatolia region Turkey. Methods This cross‐sectional population‐based study was conducted at Sivas Province among population aged 40 years over. The diagnosis XFS made when exfoliative material found on anterior lens capsule or iris slit‐lamp examination. subjects were divided into an group a non‐ according to presence material, groups compared for...
Diabetic retinopathy is one of the most common eye diseases faced by diabetic patients. It a slow-progressing complication that results from damage to blood vessels retina.To investigate role adiponectin and inflammatory cytokines in vitreous rats.The study was conducted 3-4-month-old male albino Wistar rats (180-240 g). The animals were divided into 2 groups (n = 40 each group): diabetes group control group. A single dose streptozotocin (STZ) (45 mg/kg) citrate buffer (0.1 M; pH 4.5)...
The aim of this study is to determine the effects magnetic field via cell phones on some blood parameters and neurons in brain rats. Animals have been classified into three groups: control, Magnetic Field (MF), F2 groups. Throughout study, were placed wall cages. Rats exposed during prenatal postnatal periods until they 80 days old. During exposure procedure rats was that phone standby mode for a whole day talking 30 min per day. waves caused an increased glucose level from 96.52 ± 5.64...
Salvia L., the largest genus of family Lamiaceae, is composed many well-known plants medicinal value.This study provides first data on micromorphology, myxocarpy, mineral content and in vitro antimicrobial antiproliferative activities mericarps pilifera, considered to be a vulnerable endemic species from Turkey.The macro-and micromorphological mericarp traits were documented illustrated via stereo microscopy scanning electron microscopy.Mineral was analyzed using ICP-MS.Ethanol extract...
Purpose: Nonhealing wounds are a serious problem of diabetic patients. Salvia species traditionally used for the treatment wounds. The aim study was to investigate effects ointment prepared with ethanol extract obtained from aerial parts hypargeia, an endemic plant Turkey, on rat incisional and excisional skin Materials Methods: Male Wistar albino rats (n: 60) were divided into five groups. Diabetes induced two concentrations (0.5% 1%) ointments applied 7 14 days. Fito cream chosen as...
Evernia prunastri (L.) Ach, belonging to Parmeliaceae, is an important lichen species in Turkey. Previous studies was reported that E. have significant antioxidant, antimicrobial and anticancer compounds its structure. Although antiproliferative effects of are determined some types cancer, there little information about the pathway this activity. Accordingly, we aimed determine association between anti-proliferative activities extracts with cellular apoptotic pathway. Determination cell...
Vincetoxicum cinsinin tıbbi özellikleri uzun zamandır bilinmektedir. Bazı türlerinin yaprakları, kuru tohumları ve rizomları geleneksel tıpta incinme, uyuz, nevroz, skrofula, sıtma, yara, ateş, rüptür eksternal kanserlerin tedavisinde kullanılmaktadır. Bu çalışma, V. canescens subsp. cancescens pedunculata (endemik) tohumlarının anti(miko)bakteriyel, antifungal antiproliferatif aktivitelerini değerlendirmeye odaklanmıştır. İki bitkinin etanol hekzan ekstreleri üç fungal suşa (Candida...
The current study investigated the efficacy of methotrexate (MTX) on liver tissue cells Balb/c mice at ultrastructural level using transmission electron microscopy.
PURPOSE: This study measured serum hypoxia-inducible factor-1 (HIF-1α) and survivin levels in patients with diabetes investigated their association the severity of retinopathy. METHODS: included 88 type 2 mellitus who underwent routine eye examinations. Three groups were created. Group 1 consisted without diabetic non-proliferative 3 proliferative To measure HIF-1α levels, venous blood samples collected from patients. RESULTS: The mean 1, 2, 17.30 ± 2.19, 17.79 2.34, 14.19 2.94 pg/ml,...
Background Environmental pollution, including exposure to carbon tetrachloride (CCl4), poses serious health risks, particularly through oxidative stress, which may lead neurodegenerative damage. Antioxidants, especially those found in natural products, show potential mitigating these toxic effects. Pomegranate juice (PJ), rich bioactive phytochemicals, has demonstrated antioxidant, anti-inflammatory, and neuroprotective properties. Objective This study aimed investigate the protective...
Objective: In this study, nine commercial Nucleic Acid Amplification Test Systems (NAATs) were evaluated for diagnostic performance of Mycobacterium tuberculosis complex (MTBC) from smear positive sputum species (SPss) and negative specimens (SNss). Methods: Sixty SPss 55 SNss examined microscopically by Ehrlich Ziehl Neelsen (EZN) staining method, also inoculated on Löwenstein Jensen (LJ) medium culture. The sensitivity specificity NAATs calculated according to LJ culture method accepted as...
Objective: The aim of this study was to examine the in vivo wound healing potential Salvia huberi Hedge (endemic Turkey) on excision and incision models diabetic rats. Method: Male Wistar albino rats, 3-4 months old weighing 180-240g were used. animals randomly divided into five groups including Control, Vehicle Fito reference, two different concentrations (0.5% 1% weight/weight (w/w)) ethanol extract investigated both streptozocin-induced rats using macroscopic, biomechanical, biochemical,...
In this study, we aimed to investigate the effects of 3-benzoyl-7-hydroxy coumarin compound on apoptotic markers in kidney tissues rats treated with Aluminum(Alu). 28 Wistar albino male were divided into four groups (n = 7) as: Control Group: 1 ml/kg 0.9% NaCl was administered by oral gavage every other day during experiment. Aluminium (Alu) Alu prepared water and given intraperitoneal(i.p) for 30 days at an excess 8.3 mg/kg/day. Treatment 10 mg/kg 3-Benzoyl-7-Hydroxy Coumarin days. + i.p...