A5074378650- Prenatal Substance Exposure Effects
- Homelessness and Social Issues
- Gestational Diabetes Research and Management
- Birth, Development, and Health
- COVID-19 and healthcare impacts
- Substance Abuse Treatment and Outcomes
- Maternal Mental Health During Pregnancy and Postpartum
- Misinformation and Its Impacts
- Data-Driven Disease Surveillance
- Alcohol Consumption and Health Effects
- Ubiquitin and proteasome pathways
- Retinoids in leukemia and cellular processes
- Epilepsy research and treatment
- Antibiotics Pharmacokinetics and Efficacy
- interferon and immune responses
- Inflammasome and immune disorders
- Drug-Induced Ocular Toxicity
- Chronic Lymphocytic Leukemia Research
- Mobile Health and mHealth Applications
- COVID-19 Clinical Research Studies
- Alcoholism and Thiamine Deficiency
- Pharmacological Effects and Toxicity Studies
- Per- and polyfluoroalkyl substances research
- Acute Lymphoblastic Leukemia research
- Electrolyte and hormonal disorders
University of Tennessee at Knoxville
2024
Centers for Disease Control and Prevention
2007-2024
National Center on Birth Defects and Developmental Disabilities
2007-2023
Vanderbilt University
2023
University of Iowa
2021-2022
University of Iowa Hospitals and Clinics
2021
Laboratoire de Biophotonique et Pharmacologie
2020
Conference Board
2019
IFC Research (United Kingdom)
2019
The Royal Melbourne Hospital
2018
There is no known safe amount of alcohol consumption during pregnancy; drinking pregnancy can cause fetal spectrum disorders and might increase the risk for miscarriage stillbirth (1). The prevalence among pregnant women increased slightly 2011-2018; however, more recent estimates are not yet reported (2). CDC estimated self-reported current (at least one alcoholic drink in past 30 days) binge (consuming four or drinks on at occasion adults aged 18-49 years, overall by selected...
Children and adolescents affected by prenatal exposure to alcohol who have brain damage that is manifested in functional impairments of neurocognition, self-regulation, adaptive functioning may most appropriately be diagnosed with neurobehavioral disorder associated exposure. This Special Article outlines clinical implications guidelines for pediatric medical home clinicians identify, diagnose, refer children regarding Emphasis given reported or observable behaviors can identified as part...
To evaluate the evolution of fetal alcohol spectrum disorder prevention practices including awareness and use recently published tools.Fellows American College Obstetricians Gynecologists were asked about their knowledge, opinions, practice regarding alcohol-related care. Eight hundred obstetrician-gynecologists (ob-gyns) selected; 48.1% returned survey.The majority (66.0%) indicated that occasional consumption is not safe during any period pregnancy. There was no consensus when if alcohol's...
Background Women continue to drink alcohol during pregnancy despite Surgeon Generals' Advisory statements and educational efforts about the dangers. Purpose This focus group research study examined women's knowledge beliefs consumption its risks along with related perceptions of social influences information sources in order inform future messaging. Methods The included 20 groups 149 reproductive-age women segmented by age, status, race/ethnicity. Results Discussion acknowledged consequences...
Pregnant women with opioid use disorder (OUD) are at risk of overdose, infectious diseases, and inadequate prenatal care. Additional risks include adverse pregnancy infant outcomes, such as preterm birth neonatal abstinence syndrome. Management treatment OUD during associated improved maternal outcomes. Professional organizations, including the American College Obstetricians Gynecologists, recommend offering agonist pharmacotherapy (i.e., methadone or buprenorphine) combined behavioral...
Abstract Linear ubiquitination is a post-translational modification that controls many immune signaling pathways. ubiquitin chains are added to targets by LUBAC and removed OTULIN, thus the opposing actions of OTULIN critical for homeostasis. To understand mechanisms how inflammation, we leveraged use biospecimens from patients with novel bi-allelic mutation. These have pyoderma gangrenosum (PG), an extremely rare inflammatory skin disease. mutations been previously described cause systemic...
Abstract Prenatal exposure to alcohol is a leading preventable cause of birth defects and developmental disabilities. Individuals exposed during fetal development can have physical, mental, behavioral, learning disabilities, with lifelong implications. These conditions are known as spectrum disorders (FASDs). Health care professionals play crucial role in identifying women at risk for an alcohol-exposed pregnancy the effects prenatal among individuals. The Centers Disease Control...
Aim Angioedema is a nonpitting edema that can lead to death secondary airway obstruction. Previously, staging system based on localization of the angioedema was proposed for risk stratification likelihood need admission or intervention. This study aims evaluate as method predicting Methods retrospective chart review cases presented an academic emergency department (ED) from August 1, 2006, January 31, 2018. Data were collected location swelling, treatment setting, and medical procedural...
The consumption of alcohol and other substances during pregnancy can impair prenatal development. While scientifically informed public health measures have raised awareness the risks harmful substance exposures, use continues to rise. successful dissemination consistent messaging, care professional education training, universal implementation clinical interventions may help reduce drinking in prevent fetal spectrum disorders (FASDs), a constellation developmental disabilities birth defects...
Stay-at-home orders and social distancing recommendations, combined with COVID-19 concerns, have caused significant disruptions in daily life. Throughout the pandemic, vulnerable populations, commonly seen within University of Iowa emergency department, been more negatively affected by COVID-19. To assess how needs population cared for department changed response to pandemic. The Center Medicare Medicaid Services (CMS) risk assessment was adapted, covering 13 specific domains, changes...
We present the case of a 21-year-old man admitted to intensive care unit with multi-organ failure due multidrug-resistant tuberculosis (TB). TB treatment initially comprised moxifloxacin, ethambutol, linezolid and amikacin administered intravenously. Due suspected moxifloxacin-induced liver injury, we stopped all fluoroquinolones switched bedaquiline (BDQ), which is only available in tablets for oral administration. Since our patient had be fed through nasogastric tube (NGT), BDQ was after...
Abstract Hurricane Katrina caused immense upheaval and disrupted many lives. Among those affected were pregnant women. A public service announcement, website content, a fact sheet developed to inform women about the issues that could potentially affect their health of babies. The aim these products was provide messages captured attention intended audience amid challenging environment an emergency situation. Message dissemination methods—television, radio, websites—were carefully selected,...
Background Risky alcohol use can cause a range of negative consequences, including motor vehicle crashes, intimate partner violence, and medical conditions such as hypertension, gastritis, liver disease, various cancers [1]. Alcohol during pregnancy result in miscarriage, stillbirth, fetal spectrum disorders (FASDs) [2,3]. Over thirty years research has shown that screening brief intervention (SBI) is effective at reducing risky drinking. Yet, it not been integrated widely into clinical...
Society of Critical Care Medicine; 28th Educational and Scientific Symposium; San Francisco, California, USA; January 23-27, 1999: Poster Presentations: Hall