A5070110315- Antibiotic Use and Resistance
- Pneumonia and Respiratory Infections
- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
- Nosocomial Infections in ICU
- Pneumocystis jirovecii pneumonia detection and treatment
- Patient Satisfaction in Healthcare
- Nicotinic Acetylcholine Receptors Study
- Antibiotic Resistance in Bacteria
- Cytomegalovirus and herpesvirus research
- Infectious Encephalopathies and Encephalitis
- Pharmacological Receptor Mechanisms and Effects
- Cholinesterase and Neurodegenerative Diseases
- Potassium and Related Disorders
- Biomedical and Engineering Education
- Tuberculosis Research and Epidemiology
- Pregnancy and Medication Impact
- Respiratory Support and Mechanisms
- Neuroscience and Neuropharmacology Research
- Biotechnology and Related Fields
- Blood Pressure and Hypertension Studies
- Hematopoietic Stem Cell Transplantation
- Emergency and Acute Care Studies
- Healthcare Systems and Practices
- Bacterial Identification and Susceptibility Testing
Chinese PLA General Hospital
2020-2022
Chinese People's Liberation Army
2018-2020
The Military General Hospital of Beijing PLA
2013
Background: The assessment of antibiotic use for acute upper respiratory infections (AURIs) is important to promote the appropriateness prescribing. Evaluation prescriptions AURIs at a national level very limited in China. Objective: To investigate outpatient Chinese hospitals. Methods: This study used data from over 10 million and emergency department visits AURIs, which contained information on drug prescription diagnosis, 94 cities 28 provinces mainland Antibiotic rates various subgroups...
Objective We aimed to evaluate the validity of an algorithm classify diagnoses according appropriateness outpatient antibiotic use in context Chinese free text. Setting and participants A random sample 10 000 visits was selected between January April 2018 from a national database for monitoring rational drugs, which included data 194 secondary tertiary hospitals China. Research design Diagnoses were classified as tier 1 if associated with at least one condition that ‘always’ justified use; 2...
Background: Antibiotic use in pregnant women at the national level has rarely been reported China. Objectives: We aimed to investigate antibiotic prescriptions during pregnancy ambulatory care settings Methods: Data of 4,574,961 visits from October 2014 April 2018 were analyzed. Percentages by different subgroups and various diagnosis categories proportions inappropriate for estimated. Food Drug Administration (FDA) used describe prescription patterns. The 95% confidence intervals (CIs)...
ABSTRACT Drug addiction is thought to result from an intractable and aberrant learning memory in response drug‐related stimulation, cholinergic neurotransmission plays important role this process. Phosphatidylethanolamine‐binding protein (PEBP) the precursor of hippocampal neurostimulating peptide (HCNP), 11 amino acid that enhances production choline acetyltransferase (ChAT) assists development projections medial septal nuclei hippocampus. However, whether PEBP involved drug remains...
Stimulation of the µ‑opioid receptor activates extracellular signal‑regulated kinase (ERK), however, mechanism by which this occurs remains to be elucidated. Phosphatidylethanolamine‑binding protein (PEBP) has been reported act as a negative regulator ERK cascade (Raf‑MEK‑ERK) binding Raf‑1 kinase. In present study, role PEBP in receptor‑mediated activation was investigated Chinese hamster ovary/µ cells and SH‑SY5Y cells, well human embryonic kidney 293 expressing other types G...
Abstract Postoperative pulmonary complications (PPCs) are a major cause of postoperative morbidity, mortality, and longer hospital stays. Expectorants widely used during the perioperative period to reduce PPCs. This study aimed compare clinical effectiveness between ambroxol (AMB) N ‐acetylcysteine (NAC) in patients undergoing surgery. A multicenter, retrospective cohort was conducted using deidentified medical records from information system. Between July 1, 2015, November 30, 2017, aged...
Objective: To investigate the utilization of antibiotics in emergency departments (EDs) class Ⅲ general hospitals China. Methods: Data from a national monitoring network for rational use drugs was used. The data included prescriptions EDs 114 30 provinces (autonomous regions, municipalities) A total 10 260 595 October 1, 2014 to December 31, 2016 were extracted. Anatomical Therapeutic Chemical Classification/Defined Daily Dose (DDD) system used classification and calculation antibiotic...
Abstract Background and Aims At present, the clinical burden treatment pattern of hyperkalaemia among outpatients in China is not well characterized. The aim this study was to evaluate disease distribution China. Method Data were derived from Beijing Center for Rational Use Drugs, which contains primary records 157 hospitals, covering 30 provinces Patients who accessed (aged >=≥18 years old) with record(s) serum potassium (S-K) between 2015.1.1- 2017.12.31 included. laboratory test,...
To evaluate the rationality of antibiotic use in outpatient and emergency departments some class 3A hospitals China through International Network for Rational Use Drugs(INRUD).The prescriptions were collected from 78 25 provinces INRUD during 2014-2015. The basic information evaluated.A total 447 894 antibiotics analyzed. From 2014 to 2015, qualified rate increased 91.52% 93.08%, was similar(11.72% 12.04%). major irrational prescription type inappropriate prescription, including...