Lin Zhuo

ORCID: 0000-0001-9188-702X
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • COVID-19 Clinical Research Studies
  • Diabetes Treatment and Management
  • Pharmaceutical Practices and Patient Outcomes
  • Cancer-related molecular mechanisms research
  • Molecular Sensors and Ion Detection
  • Nanoparticles: synthesis and applications
  • Nutritional Studies and Diet
  • Topic Modeling
  • Colorectal Cancer Screening and Detection
  • Metal-Organic Frameworks: Synthesis and Applications
  • Helicobacter pylori-related gastroenterology studies
  • Prostate Cancer Treatment and Research
  • RNA modifications and cancer
  • Advanced Nanomaterials in Catalysis
  • MicroRNA in disease regulation
  • Biomedical Text Mining and Ontologies
  • Electrochemical Analysis and Applications
  • Dementia and Cognitive Impairment Research
  • Conducting polymers and applications
  • Antibiotic Use and Resistance
  • Workplace Health and Well-being
  • Nanocluster Synthesis and Applications
  • COVID-19 and healthcare impacts
  • Fire Detection and Safety Systems
  • Advanced Battery Materials and Technologies

Peking University
2016-2025

Peking University Third Hospital
2019-2025

Central South University
2024-2025

Xiangya Hospital Central South University
2024-2025

Huazhong Agricultural University
2024

New York University
2024

UNSW Sydney
2024

Hulunbuir University
2024

Anhui Provincial Children's Hospital
2023-2024

Chongqing Technology and Business University
2019-2024

Cancer-associated fibroblasts (CAFs) contributes to overall tumor progression. In the current survey, we explored ability of microRNA-20a (miR-20a) within these CAF-derived exosomes influence non-small-cell lung cancer (NSCLC)

10.1002/ctm2.989 article EN cc-by Clinical and Translational Medicine 2022-07-01

We investigate interactions between graphene oxide and a Pb2+-dependent DNAzyme, based on which Pb2+ sensor with high sensitivity, selectivity tunable dynamic range is developed.

10.1039/c1cc11486g article EN Chemical Communications 2011-01-01

International hospital-based studies have indicated a high risk of cognitive impairment after stroke, evidence from community-based in China is scarce. To determine the prevalence post-stroke (PSCI) and its subtypes stroke survivors residing selected rural urban Chinese communities, we conducted community-based, cross-sectional study 599 patients accounting for 48% all registered 4 who had suffered confirmed strokes undergone assessments via Montreal Cognitive Assessment (MoCA), Mini-Mental...

10.1371/journal.pone.0122864 article EN cc-by PLoS ONE 2015-04-13

Biomedical named entity recognition (BioNER) is a basic and important medical information extraction task to extract entities with special meaning from texts. In recent years, deep learning has become the main research direction of BioNER due its excellent data-driven context coding ability. However, in task, problem poor generalization instability.we propose hierarchical shared transfer learning, which combines multi-task fine-tuning, realizes multi-level fusion between underlying features...

10.1186/s12859-021-04551-4 article EN cc-by BMC Bioinformatics 2022-01-04

Type 2 diabetes mellitus (T2DM) and dementia cause heavy health burden in mainland China, where few studies have investigated the association between glucose-lowering agents risk. We aimed to assess use of thiazolidinediones (TZDs) incidence a Chinese population with T2DM.

10.1111/1753-0407.13352 article EN cc-by Journal of Diabetes 2023-01-20

<title>Abstract</title> Background Renal dysfunction is a frequent complication after kidney transplantation, leading to poor prognosis and increased mortality. Abnormal blood lipids are closely related renal dysfunction, yet their associations mechanisms among transplant recipients remain unclear. This study aimed establish an effective risk prediction model for RTRs based on abnormal lipid profiles using machine learning. Methods retrospective cohort recruited of 345 followed up one year...

10.21203/rs.3.rs-5823279/v1 preprint EN cc-by Research Square (Research Square) 2025-01-15

The effects of sodium-glucose co-transporter 2 inhibitors (SGLT-2i) on dementia risk have not been assessed in the Chinese population. We aimed to assess association between use SGLT-2i and incidence a mainland A target trial vs. dipeptidyl peptidase 4 (DPP-4i) was emulated, with cohorts type diabetes mellitus patients who were new users or DPP-4i being assembled using Yinzhou Regional Health Care Database. Inverse probability treatment weighting (IPTW) applied control potential confounding,...

10.1111/dom.16239 article EN Diabetes Obesity and Metabolism 2025-02-10

OBJECTIVE Preclinical studies in animals have suggested potential neuroprotective effects of sodium–glucose cotransporter 2 inhibitors (SGLT-2is), but no epidemiological study has investigated the SGLT-2is on epilepsy risk. We aimed to assess association between use and incidence. RESEARCH DESIGN AND METHODS emulated a target trial comparing dipeptidyl peptidase 4 (DPP-4is) based Yinzhou Regional Health Care Database. Cohorts patients with type diabetes mellitus who were new users an SGLT-2i...

10.2337/dc24-2532 article EN Diabetes Care 2025-03-25

&lt;p dir="ltr"&gt;Objective: Preclinical studies in animals suggested potential neuroprotective effects of sodium-glucose co-transporter 2 inhibitors (SGLT-2i), but no epidemiological study has investigated the SGLT-2i on epilepsy risk. We aimed to assess association between use and incidence.&lt;/p&gt;&lt;p dir="ltr"&gt;Research Design Methods: emulated a target trail comparing dipeptidyl peptidase 4 (DPP-4i) based Yinzhou Regional Health Care Database. Cohorts T2DM patients who were new...

10.2337/figshare.28513529.v1 preprint EN cc-by-nc-sa 2025-03-25

&lt;p dir="ltr"&gt;Objective: Preclinical studies in animals suggested potential neuroprotective effects of sodium-glucose co-transporter 2 inhibitors (SGLT-2i), but no epidemiological study has investigated the SGLT-2i on epilepsy risk. We aimed to assess association between use and incidence.&lt;/p&gt;&lt;p dir="ltr"&gt;Research Design Methods: emulated a target trail comparing dipeptidyl peptidase 4 (DPP-4i) based Yinzhou Regional Health Care Database. Cohorts T2DM patients who were new...

10.2337/figshare.28513529 preprint EN cc-by-nc-sa 2025-03-25

Abstract As food additives, titanium dioxide nanoparticles (TiO 2 NPs) have been widely used in various products that are usually simultaneously consumed with a high content of sugar, thus necessitating research on the effect TiO NPs glucose homeostasis. We conducted an animal study to explore orally administrated absorption and metabolism rats at 0, 2, 10 50 mg kg –1 body weight day for 30 90 days. The results showed oral exposure caused slight temporary hypoglycemic days post‐exposure but...

10.1002/jat.3589 article EN Journal of Applied Toxicology 2018-01-19

Heavy menstrual bleeding (HMB) has been shown to have a profound negative impact on women's quality of life and lead increases in health care costs; however, data HMB among Chinese population is still rather limited. The present study therefore aimed determine the current prevalence risk factors subjectively experienced community sample reproductive-age women, evaluate its effect daily life. We conducted questionnaire survey 2356 women aged 18–50 years living Beijing, China, from October...

10.1186/s12905-019-0726-1 article EN cc-by BMC Women s Health 2019-02-04

Mechanisms of the enhancement photocatalytic activity p–n heterojunction BiOBr/La<sub>2</sub>Ti<sub>2</sub>O<sub>7</sub> and NO oxidation are proposed.

10.1039/c9cy02230a article EN Catalysis Science & Technology 2019-12-16

Treatments for non-small cell lung cancer (NSCLC) have improved tremendously, but therapeutic resistance is a common and major clinical challenge in treatment. Methyltransferase-like 3 (METTL3) ribonucleic acid (RNA) methyltransferase that has crucial functions the development progression of cancers, including drug resistance, by regulating N6-methyladenosine (m6A) modification. However, role METTL3 NSCLC poorly understood.The expression levels AKT serine/threonine kinase 1 (AKT1) tissues...

10.21037/atm-21-6608 article EN Annals of Translational Medicine 2022-02-01

A new dihydroanthracene-based photochromic ligand was developed to construct a luminescent coordination polymer as the first sensing application, which has resulted in an outstanding MnO 4 − sensor.

10.1039/d1tc05406f article EN Journal of Materials Chemistry C 2021-12-24
Coming Soon ...