- HIV/AIDS Research and Interventions
- Intracerebral and Subarachnoid Hemorrhage Research
- Tuberculosis Research and Epidemiology
- Hearing Loss and Rehabilitation
- Pneumonia and Respiratory Infections
- Plant-based Medicinal Research
- Birth, Development, and Health
- Acute Ischemic Stroke Management
- HIV, Drug Use, Sexual Risk
- Hearing, Cochlea, Tinnitus, Genetics
- Adolescent Sexual and Reproductive Health
- Drug-Induced Hepatotoxicity and Protection
- Pediatric health and respiratory diseases
- Neurosurgical Procedures and Complications
- Gestational Diabetes Research and Management
- HIV/AIDS drug development and treatment
- Noise Effects and Management
- Nosocomial Infections in ICU
- Respiratory viral infections research
- Mycobacterium research and diagnosis
- Mechanical Circulatory Support Devices
- Pharmacological Effects of Natural Compounds
- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Intracranial Aneurysms: Treatment and Complications
Tianjin Children's Hospital
2006-2025
First Hospital of Jilin University
2001-2025
Jilin University
2001-2025
Murdoch Children's Research Institute
2016-2025
The University of Melbourne
2016-2025
Peking University
2015-2025
Royal Children's Hospital
2018-2025
Beijing Chao-Yang Hospital
2022-2025
Capital Medical University
2014-2025
Fudan University
2025
Objective To evaluate pulmonary function and clinical symptoms in coronavirus disease 2019 (COVID-19) survivors within 3 months after hospital discharge, to identify risk factors associated with impaired lung function. Methods material COVID-19 patients were prospectively followed-up tests characteristics for following discharge from a Wuhan, China between January February 2020. Results 647 included. 87 (13%) presented weakness, 63 (10%) palpitations 56 (9%) dyspnoea. The prevalence of each...
<h3>Importance</h3> Single self-reported measures of sleep duration are associated with adverse health outcomes; however, long-term patterns and their association cardiovascular events (CVEs) all-cause mortality remain unknown. <h3>Objective</h3> To determine whether trajectories vs single-measure subsequent risk CVEs mortality. <h3>Design, Setting, Participants</h3> The Kailuan study is a prospective, population-based cohort that began in 2006. present included 52 599 Chinese adults without...
In real situations, people are often faced with the option of voluntary contribution to achieve a collective goal, for example, building dam or fence, in order avoid an unfavorable loss. Those who do not donate, however, can free ride on others' sacrifices. As result, cooperation is difficult maintain, leading enduring collective-risk social dilemma. To address this issue, here we propose simple yet effective theoretical model threshold public goods game risk and focus effect emergence...
Background: Biomedical HIV prevention trials enroll sexually active women at risk of and often discontinue study product during pregnancy. We assessed factors for pregnancy acquisition, the effect on time off drug in Prevention Trials Network 039. Methods: A total 1358 negative, herpes simplex virus type 2-seropositive from South Africa, Zambia, Zimbabwe were enrolled followed up to 18 months. Results: 228 pregnancies occurred; due accounted 4% woman-years follow-up among women. Being...
Abstract Background Cases of refractory Mycoplasma pneumoniae pneumonia have been increasing recently; however, whether viral coinfection or macrolide-resistant M. infection contribute to the development remains unclear. This study aimed investigate impacts and on in hospitalized children build a model predict severe disease course. Methods Nasopharyngeal swabs sputum specimens were collected from patients with community-acquired meeting our protocol who admitted Shanghai Children’s Medical...
Crucial to the pathogenesis of tuberculosis (TB)-causing pathogen Mycobacterium is its ability subvert host immune defenses promote intracellular survival. The mammalian cell entry protein 3E (Mce3E), located in region difference 15 M. genome and absent bovis bacillus Calmette-Guérin, has an essential role facilitating internalization cells by mycobacteria. However, relatively little known about Mce3E modulation innate responses. In this study, we demonstrate that inhibits activation ERK1/2...
We sought to understand the multilevel syndemic factors that are concurrently contributing HIV epidemic among women living in US. specifically examined community, network, dyadic, and individual explain vulnerability within a socioecological framework. gathered qualitative data (120 interviews 31 focus groups) from subset of ages 18–44 years (N = 2,099) enrolled HPTN 064 seroincidence estimation study across 10 US communities. analyzed 4 diverse locations: Atlanta, New York City (the Bronx),...
BACKGROUND:Adverse events are under-appreciated negative consequences that significant clinical problems for patients undergoing anti-MDR-TB treatment due to longer duration of and more need concurrent use multiple second-line drugs. The aim this study was determine the incidence adverse their impact on MDR-TB therapy outcome, identify possible drug-event pairs in China. MATERIAL AND METHODS:An ambispective cohort conducted based hospital medical records, which included a retrospective...
The rapid spread of Clostridium difficile NAP1/BI/027 (C. 027) has become one the leading threats healthcare-associated infections worldwide. However, C. 027 have been rarely reported in Asia, particularly China. In this study, we identified a rare bloodstream infection (BSI) from three isolates patient during repeated hospital admission. This finding triggered retrospective epidemiological study to scan all cases and strains emerged ward past years. Using medical personnel interviews,...
Purpose: We aimed to retrospectively analyze the clinical features, laboratory and imaging results, predictors of poor prognosis for patients with an initial diagnosis autoimmune encephalitis (AE) at Affiliated Hospital Zunyi Medical University. Methods: Fifty AE who were admitted our hospital from May 2014 2018 enrolled retrospectively. Clinical characteristics experimental test data, including neutrophil-to-lymphocyte ratio (NLR), collected medical records within 24 hours admission....
Aims To report the weight loss findings after first year of a lifestyle intervention trial among women with gestational diabetes mellitus (GDM). Methods A total 1180 GDM were randomly assigned (1:1) to receive 4‐year (intervention group, n = 586) or standard care (control 594) between August 2009 and July 2011. Major elements included 6 face‐to‐face sessions study dieticians two telephone calls in year, individual each subsequent year. Results Among 79% participants who completed 1 trial,...
BackgroundLymphatic malformations are common congenital vascular lesions. Neither surgical resection nor other treatments have been found to be effective for invasive cases. Recent research has suggested that sirolimus is in treating complex lymphatic (LMs). We aimed evaluate the effectiveness and safety of oral children living with LMs our hospital.MethodsFifty-six cases treated were collected from Shanghai Children's Medical Centre between June 2016 March 2019. All confirmed either by...
Importance In 2009, the US National Academy of Medicine (NAM) released revised gestational weight gain (GWG) guidelines, which were established primarily for White North American women and may be unsuitable Asian women. 2021, Chinese Nutrition Society (CNS) its GWG but their applicability requires re-examination. Objective To compare differences between CNS NAM recommendations in association with health outcomes offspring Design, Setting, Participants this bidirectional cohort study,...
Background Diabetic kidney disease (DKD) is a common diabetic complication and increases the complexity of diabetes management. No prospective study has focused on association between DKD Life's Essential 8 (LE8). Our aims to examine LE8 risk. Methods Results A total 7605 participants, aged 54.32±9.77 years, 4688 56.11±10.38 were included in longitudinal trajectory analyses, respectively, from 2006 2020. The was confirmed using data collected during each follow-up. based 4 health behaviors...