- Diabetes, Cardiovascular Risks, and Lipoproteins
- Lipoproteins and Cardiovascular Health
- Cardiovascular Health and Disease Prevention
- Adipokines, Inflammation, and Metabolic Diseases
- Clostridium difficile and Clostridium perfringens research
- Viral Infections and Immunology Research
- Cardiac Fibrosis and Remodeling
- Cardiovascular Disease and Adiposity
- Diabetes Treatment and Management
- Cardiomyopathy and Myosin Studies
- Blood Pressure and Hypertension Studies
- Health disparities and outcomes
- Gut microbiota and health
- Heart rate and cardiovascular health
- Cardiovascular Health and Risk Factors
- Microscopic Colitis
Hubei University of Medicine
2024-2025
Tianjin Medical University General Hospital
2023-2024
Tianjin Medical University
2023
Background Diabetic kidney disease (DKD) is a common diabetic complication and increases the complexity of diabetes management. No prospective study has focused on association between DKD Life's Essential 8 (LE8). Our aims to examine LE8 risk. Methods Results A total 7605 participants, aged 54.32±9.77 years, 4688 56.11±10.38 were included in longitudinal trajectory analyses, respectively, from 2006 2020. The was confirmed using data collected during each follow-up. based 4 health behaviors...
Abstract Background The precise pathways connecting insulin resistance (IR) to atherosclerotic cardiovascular disease (ASCVD) remain undefined. present study aimed examine the mediating role of arterial stiffness in association between IR and ASCVD, providing epidemiology insights into potential mechanisms driving incident ASCVD. Methods A total 59,777 participants from Kailuan Study Arterial Stiffness Subcohort who were free ASCVD at baseline enrolled study. was assessed using baPWV by...
Zhaogui Wu, Jingli Gao, Shuohua Chen, Guodong Wang, Hangkuan Liu, Xuezhu Pengfei Sun, Xuefang Yu, Qing Yang, Shouling Xin Zhou
Abstract Objective The purpose of the study was to construct potential diagnostic model immune-related genes during development heart failure caused by idiopathic dilated cardiomyopathy. Method GSE5406 and GSE57338 were downloaded from GEO website ( https://www.ncbi.nlm.nih.gov/geo/ ). CIBERSORT used for evaluation immune infiltration in cardiomyopathy (DCM) GSE5406. Differently expressed calculated limma R package visualized volcano plot. Immport, TISIDB, InnateDB. Then differential (IRDGs)...
This study aimed to longitudinally investigate the association between circulating neutrophil count and progression of arterial stiffness ascertain whether resting heart rate (RHR) mediates this association. The current included 56,760 participants with brachial-ankle pulse wave velocity (baPWV) measurements from a real-life, prospective cohort in China. associations (exposure) baseline baPWV, baPWV progression, (outcomes), as well RHR (mediator) were assessed using multivariable linear Cox...
Limited information exists regarding whether circulating microbiota could predict long-term clinical outcomes following ST-segment elevation myocardial infarction (STEMI). A total of 244 consecutive patients with STEMI were followed for 2.8 years, and 64 first major adverse cardiovascular events (MACEs) recorded. Both abundance [Corynebacterium tuberculostearicum (HR, 1.28; 95% CI, 1.03-1.58) Staphylococcus aureus (S. aureus) 1.16; 1.02-1.33) ] clusters (Cluster 2 versus Cluster 1: HR, 1.84;...