A5100451659- Peptidase Inhibition and Analysis
- Prostate Cancer Treatment and Research
- Protease and Inhibitor Mechanisms
- Crystallization and Solubility Studies
- Advanced biosensing and bioanalysis techniques
- X-ray Diffraction in Crystallography
- Cancer-related molecular mechanisms research
- Immune Cell Function and Interaction
- Receptor Mechanisms and Signaling
- Immunotherapy and Immune Responses
- Cancer Immunotherapy and Biomarkers
- Nanoplatforms for cancer theranostics
- Ferroptosis and cancer prognosis
- Parasitic Infections and Diagnostics
- Cancer, Hypoxia, and Metabolism
- Diabetes Treatment and Management
- Biosensors and Analytical Detection
- Gut microbiota and health
- RNA modifications and cancer
- CRISPR and Genetic Engineering
- Inflammatory mediators and NSAID effects
- Advancements in Transdermal Drug Delivery
- Scoliosis diagnosis and treatment
- RNA Interference and Gene Delivery
- Wnt/β-catenin signaling in development and cancer
Quest Diagnostics (United States)
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2024
Chongqing Medical University
2024
Kunming University of Science and Technology
2024
Tianjin Medical University
2022-2024
University of Tennessee Health Science Center
2020-2024
Jiangsu Provincial Hospital of Traditional Chinese Medicine
2023-2024
University of Shanghai for Science and Technology
2024
Jiaying University
2024
Shanghai University of Traditional Chinese Medicine
2022-2024
Groundwater has been a relatively safe water source and associated with series of global pressing issues. It can, however, be vulnerable to pathogen contamination exhibit risks public health. While groundwater often considered closed ecosystem, it is important understand the transport pathogens into within groundwater-dependent ecosystems in context their physiological characteristics, soil/sediment texture, hydrogeological climatic conditions. The rapid progress monitoring modeling tools...
To investigate the therapeutic effects of static magnetic field (SMF) and its regulatory mechanism in repair osteoarthritic cartilage.Fourteen-week-old female C57BL/6 mice were randomly divided into sham operation group osteoarthritis (OA) groups with without SMF application. was applied at 200 mT for two consecutive weeks. Changes knee cartilage examined by histomorphometry, chondrogenesis migration endogenous stem cells assessed. The expression SRY-related protein 9 (SOX9), Collagen type...
Abstract Gametophyte development in angiosperms occurs within diploid sporophytic structures and requires coordinated development; e.g., of the male gametophyte pollen depends on surrounding tissue, tapetum. The mechanisms underlying this interaction remain poorly characterized. peptide CLAVATA3/EMBRYO SURROUNDING REGION-RELATED 19 (CLE19) plays a “braking” role preventing harmful overexpression tapetum transcriptional regulators to ensure normal Arabidopsis . However, CLE19 receptor is...
Flower development, a vital phase in the plant life cycle, involves intricate physiological and morphogenetic processes driven by dynamic molecular metabolic processes. However, specific mechanisms metabolite accumulation patterns during Gastrodia elata flower development remain largely unknown. This study utilized Illumina’s next-generation sequencing to analyze G. transcriptome across three critical developmental stages, capturing gene expression changes, particularly those related...
Background Pneumonia mortality can be decreased by early antibiotic administration. Pathogen identification aims to minimize inappropriate, nontargeted exposure. Molecular assays expedite organism through nucleic acid detection and antimicrobial resistance screening for genetic markers.
Shewanella putrefaciens is a typical spoilage bacteria organism in seafood. The adhesion ability of three S. strains (HR-15, JR-18, HC-71) isolated from putrefied tilapia were evaluated by mucus vitro and intestinal vivo. results the inoculated fish fillets refrigerated both showed that was positively correlated with ability. High-throughput sequencing GC-MS high also significantly changed flora fish, causing an increase such as Plesionomas, Macellibacteroides, Acinetobacter, Legionella,...
Traditional Chinese medicine (TCM) has from ancient times been applied in China for the treatment of breast cancer with its own unique theoretical system. Sanhuang decoction composed astragalus membranaceus, prepared rhubarb, and rhizoma curcumae longae traditionally used antioxidant stress, inflammatory reaction, angiogenesis. However, role mechanism remains unknown. The present study demonstrated antitumor activity against xenografts nude mice. Notably, promoted severe necrosis induced...
Glioblastoma (GBM) is the most aggressive brain tumour in central nervous system, but current treatment very limited and unsatisfactory. PGE2 -initiated cAMP signalling via EP2 EP4 receptors involved tumourigenesis of multiple cancer types. However, whether or how contribute to GBM growth largely remains elusive.We performed comprehensive data analysis gene expression human samples determined their correlations through bioinformatics approaches. A time-resolved fluorescence energy transfer...
Inflammatory environments provide vital biochemical stimuli (i.e., oxidative stress, pH, and enzymes) for triggered drug delivery in a controlled manner. Inflammation alters the local pH within affected tissues. As result, pH-sensitive nanomaterials can be used to effectively target drugs site of inflammation. Herein, we designed nanoparticles which resveratrol (an anti-inflammatory antioxidant compound (RES)) urocanic acid (UA) were complexed with moiety using an emulsion method. These...
Monocytes and fibrinogen (FIB) play important roles in driving acute reparative inflammatory pathways after myocardial infarction (MI). In humans, there are three subsets of monocytes, namely, CD14++CD16- (Mon1), CD14++CD16+ (Mon2), CD14+CD16++ (Mon3). During the response, monocyte express high levels integrin αM β2 protease-activated receptors 1 3 to interact with FIB.However, whether is a synergistic role FIB combined Mon2 counts prioritizing patients at risk future major adverse...