- Membrane Separation Technologies
- Membrane-based Ion Separation Techniques
- Cell death mechanisms and regulation
- Cancer-related Molecular Pathways
- Liver Disease Diagnosis and Treatment
- Extraction and Separation Processes
- Membrane Separation and Gas Transport
- Nanopore and Nanochannel Transport Studies
- Recycling and Waste Management Techniques
- Eicosanoids and Hypertension Pharmacology
- Silicone and Siloxane Chemistry
- MicroRNA in disease regulation
- Hormonal Regulation and Hypertension
- Cardiac Fibrosis and Remodeling
- Innovations in Concrete and Construction Materials
- Advanced Sensor and Energy Harvesting Materials
- Surfactants and Colloidal Systems
- Sirtuins and Resveratrol in Medicine
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Health and Disease Prevention
- Electrohydrodynamics and Fluid Dynamics
- Cardiovascular Function and Risk Factors
- PARP inhibition in cancer therapy
- Surface Modification and Superhydrophobicity
- Mitochondrial Function and Pathology
Dalian Medical University
2024-2025
Second Affiliated Hospital of Dalian Medical University
2024-2025
Tiangong University
2019-2024
Huazhong University of Science and Technology
2022
Tongji Hospital
2022
General Hospital of Shenyang Military Region
2021
Background:The continued success of oncological therapeutics is dependent on the mitigation treatment-related adverse events, particularly cardiovascular toxicities.As such, there an important need to understand basic mechanisms drug toxicities in process antitumor therapy.Our aim this study was elucidate underlying sorafenib (sor)-induced cardiomyocyte damage.Methods: Primary mouse cardiomyocytes were prepared and treated with sor various other treatments.Cardiomyocyte necroptosis detected...
Background The level of monocyte to high‐density lipoprotein ratio (MHR) is associated with cardiovascular diseases. Carotid plaque (CP) an independent risk factor for However, evidence association MHR CP scarce. Methods and Results This study involved 5260 participants aged >18 years old from the Dalian health management cohort in 2014 2022. subjects were stratified into 4 groups based on quartile at baseline. Multivariable‐adjusted Cox regression models used calculate MHR‐associated...
This study aimed to determine whether remnant cholesterol (RC) and its variability can predict the onset of metabolic dysfunction-associated steatotic liver disease (MASLD) independently low-density lipoprotein (LDL-C) levels. A longitudinal cohort involving 43,065 participants who underwent at least two physical examinations was conducted. used Cox proportional hazards models assess relationships among RC quartile levels (Q1–Q4), visit-to-visit variability, risk MASLD. quantified using...
Previous research studies have linked the systemic immune inflammation index (SII), derived from a complete blood count, to metabolic dysfunction-associated steatotic liver disease (MASLD). However, evidence on relationship between longitudinal changes in SII and MASLD remains limited. This study aimed explore distinct trajectories their association with incidence. A analyzed 25,600 individuals who underwent periodic health assessments at Dalian City hospital 2014 2023. was diagnosed via...
Abstract Background This study sought to examine the associations between cardiometabolic indices and onset of metabolic dysfunction-associated steatotic liver disease (MASLD) as well its progression fibrosis. Methods comprised 25,366 subjects aged 18 years older, free MASLD at baseline, from Dalian Health Management Cohort (DHMC). Cardiometabolic include index (CMI), atherogenic plasma (AIP), triglyceride glucose (TyG), glucose-body mass (TyG-BMI), glucose-waist circumference (TyG-WC)...
Halogen-free flame retardant polyacrylonitrile (PAN) was prepared via hydrolyzing the nitrile groups of PAN using aqueous sodium carbonate solution/hydrogen peroxide followed by grafting with diphenylphosphinyl chloride. The structure original PAN, hydrolyzed (HPAN), and (FR-PAN) samples were characterized Fourier transform infrared spectroscopy, X-ray photoelectron diffraction, 1H NMR spectroscopy. thermal properties materials assessed thermogravimetric analysis. FTIR spectroscopy indicates...
Abstract Background and aims Evidence from prospective cohort studies on the relationship between metabolic dysfunction-associated steatotic liver disease (MASLD) longitudinal changes in serum ferritin (SF) still limited. This study aimed to investigate associations of SF baselines trajectories with new-onset MASLD present a discriminant model. Methods A total 1895 participants who attended health examinations at least three times hospital Dalian City 2015 2022 were included. The main...
In this paper, a novel polyvinylidene fluoride (PVDF) hollow fiber ultrafiltration membrane with uniform pore size and hydrophilic cross-linked network in matrix was developed by non‐solvent induced phase separation method. The dual role mechanism of in-situ cross-linking regulating molecular chain arrangement during preventing deterioration mechanical properties were analyzed. results demonstrated that the formed crosslinking entangled PVDF chains which improved regularity chains,...
Background: Acute myocardial infarction (MI) has got revolutionized therapeutic strategy by applying timely reperfusion therapy in a particular increase of primary percutaneous coronary intervention. Despite this cardiac remodeling following MI are very common with high mortality. A previous study claimed that AMPK played pivotal role intracellular adaptation to energy stress during ischemia. However, whether AMPKγ2 subunit an important remains poorly defined. Hypothesis: We assessed the...
Background: The continued success of oncological therapeutics is dependent on the mitigation treatment-related adverse events, particularly cardiovascular toxicities. As such, there an important need to understand basic mechanisms drug toxicities and explore differences in fundamental signaling pathways between cancer cells non-cancer for maintenance function survival these cells. Our aim this study was elucidate underlying sorafenib (Sor)-induced cardiomyocyte damage. Methods: Primary mouse...