A5020929050- Foot and Ankle Surgery
- Tendon Structure and Treatment
- Diverse Topics in Contemporary Research
- Diverse Approaches in Healthcare and Education Studies
- Orthopedic Surgery and Rehabilitation
- Engineering Applied Research
- Consumer Perception and Purchasing Behavior
- Shoulder Injury and Treatment
- Sports injuries and prevention
- Lower Extremity Biomechanics and Pathologies
- Bone Tissue Engineering Materials
- Knee injuries and reconstruction techniques
- Osteoarthritis Treatment and Mechanisms
- Bone fractures and treatments
- Musculoskeletal synovial abnormalities and treatments
- Diabetic Foot Ulcer Assessment and Management
- Peripheral Nerve Disorders
- Internet of Things and Social Network Interactions
- Educational Systems and Policies
- Periodontal Regeneration and Treatments
- Energy and Environmental Systems
- Orthopaedic implants and arthroplasty
- Surgical Sutures and Adhesives
- Korean Urban and Social Studies
- Bone and Joint Diseases
Korea University Medical Center
2016-2025
National Cancer Center
2025
Hallym University
2025
Yonsei University
2013-2025
Korea University
2012-2024
Kyung Hee Cyber University
2024
Hallym University Sacred Heart Hospital
2023
Sogang University
2023
Chonnam National University Hospital
2023
Agency for Defense Development
1970-2022
Opening the Portico Escherichia coli diacylglycerol kinase (DAGK) represents a family of integral membrane phosphotransferases that function in prokaryotic-specific metabolic pathways. Van Horn et al. (p. 1726 ) determined structure 40-kilodalton functional homotrimer E. DAGK by solution nuclear magnetic resonance spectroscopy. Each monomer comprises three transmembrane helices. The third helix from each subunit is domain-swapped to pack against first and second helices an adjacent subunit....
The amyloid precursor protein (APP) is subject to alternative pathways of proteolytic processing, leading either production the amyloid-beta (Abeta) peptides or non-amyloidogenic fragments. Here, we report first structural study C99, 99-residue transmembrane C-terminal domain APP liberated by beta-secretase cleavage. We also show that cholesterol, an agent promotes amyloidogenic pathway, specifically binds this protein. C99 was purified into model membranes where it observed homodimerize....
<h3>Background</h3> Parkinson9s disease with mild cognitive impairment (PD-MCI) is a heterogeneous entity in terms of profiles and conversion to dementia. However, the risk factors for ongoing decline patients PD-MCI are not clearly defined. <h3>Methods</h3> 51 were prospectively followed-up minimum 2 years. Subjects classified as MCI converters (n=15) or non-converters (n=36) based on whether they subsequently diagnosed PD We explored neuroanatomical characteristics using voxel morphometry...
Background: The evidence supporting best practice guidelines in the field of cartilage repair ankle are based on both low quality and levels evidence. Therefore, an international consensus group experts was convened to collaboratively advance toward opinions available key topics within ankle. purpose this article is report statements “Debridement, Curettage Bone Marrow Stimulation” developed at 2017 International Consensus Meeting Cartilage Repair Ankle. Methods: Seventy-five representing 25...
Given the increasing trend of cholecystectomy, it is imperative to reassess surgical and surveillance strategies in consideration potential long-term risks for digestive tract cancers. The objective this study was assess risk gastrointestinal (GI) hepato-biliary-pancreatic (HBP) cancer incidence after cholecystectomy. data cohort obtained from National Health Insurance Service database Korea. 715,872 patients who underwent cholecystectomy between 2004 2020 were compared 1,431,728 individuals...
Microfracture of cartilage induces migration bone-marrow-derived mesenchymal stem cells. However, this treatment often results in fibrocartilage regeneration. Growth factors such as bone morphogenetic protein (BMP)-2 induce the differentiation cells into chondrocytes, which can be used for hyaline Here, we tested hypothesis that long-term delivery BMP-2 to defects subjected microfracture regeneration high-quality hyaline-like cartilage, opposed short-term or no delivery. Heparin-conjugated...
Background: The evidence supporting best practice guidelines in the field of cartilage repair ankle are based on both low quality and levels evidence. Therefore, an international consensus group experts was convened to collaboratively advance toward opinions available key topics within ankle. purpose this article is report statements “Conservative Management Biological Treatment Strategies” developed at 2017 International Consensus Meeting Cartilage Repair Ankle. Methods: Seventy-five...
Quantitative image analysis of high-resolution computed tomography (HRCT) performed at residual volume, before and after methacholine, is a sensitive method detecting small airways involvement in asthma response to therapy targeted the airways. Since an oral anti-leukotriene reaches via circulation, present authors hypothesised that treatment with montelukast would lead improved airway patency. A double-blind crossover study compared effect versus placebo for 4 weeks 16 mild-to-moderate...
The evidence supporting best practice guidelines in the field of cartilage repair ankle are based on both low quality and levels evidence. Therefore, an international consensus group experts was convened to collaboratively advance toward opinions available key topics within ankle. purpose this article is report statements "Scaffold-Based Therapies" developed at 2017 International Consensus Meeting Cartilage Repair Ankle.Seventy-five representing 25 countries 1 territory were participated a...
Background: Treatment guidelines for cartilage lesions of the talus have been based on both low quality and levels evidence. Therefore, an international consensus group experts was convened to collaboratively advance toward opinions key topics regarding talus. The purpose this article is explain process delineate statements derived from meeting use “osteochondral autograft” osteochondral Methods: Seventy-five in repair ankle representing 25 countries 1 territory were participated a Delphi...
After the COVID-19 pandemic and spectrum of new climate change disruptions in supply chain, a holistic approach towards sustainable transportation is needed. Sustainable could benefit development from different angles; reduced traffic deaths, increased share renewable energy, higher quality transport-related infrastructure, satisfaction with public transportation, responsible consumption production, fossil fuel consumption. This study an attempt to show whereon scholars were focused...
Oncologic outcomes of conversion surgery for advanced pancreatic cancer (PC) have scarcely been reported. Therefore, this study aimed to investigate the with preoperative treatment FOLFIRINOX or gemcitabine nab-paclitaxel (GnP) patients PC including locally metastatic PC. Using National Health Insurance database between 2005 and 2020, we identified who underwent after chemotherapy GnP The were categorized based on treatment. Survival evaluated date diagnosis surgery. Among 69,183 PC, 476...
Chronic ankle instability (CAI), due to its chronic nature and biomechanical complexity, is well-suited for continuous monitoring tele-rehabilitation using wearable sensor technology. This study assessed whether a smart insole system, equipped with 4 force-sensing resistor sensors an inertial measurement unit, combined functional tests indices, could distinguish CAI patients from healthy controls. A total of 21 (23.8 ± 5.1 years) 16 controls (22.62 2.60 completed battery performance while...
Backbone nuclear magnetic resonance (NMR) assignments were achieved for diacylglycerol kinase (DAGK) in detergent micelles. DAGK is a homotrimeric integral membrane protein comprised of 121 residue subunits, each having three transmembrane segments. Assignments made using TROSY-based pulse sequences. was found to be an almost exclusively helical protein. This work points the feasibility both solving structure solution NMR methods and as primary tool structural studies other proteins similar...
Abstract Background Hueter-Volkmann's law regarding growth modulation suggests that increased pressure on the end plate of bone retards (Hueter) and conversely, reduced accelerates (Volkmann). Literature described same principle in Rat-tail model. Human spine its deformity i.e. scoliosis has also kind pattern during period which causes wedging disc or vertebral body. Methods This cross sectional study 150 patients adolescent idiopathic was done to evaluate body compare extent differential...
Herniation of the temporomandibular joint (TMJ) into external auditory canal (EAC) is a very rare condition, and it mostly occurs in patients with bony wall defects anterior EAC. The purpose this study was to evaluate clinical radiological findings treatment results TMJ herniation EAC by reviewing large sample temporal bone computed tomography (CT) scans.A retrospective study.We reviewed 985 adult CT scans evaluated presence defects, size location herniation. We enrolled 23 cases...
The osteogenic effect of culturing adipose-derived stem cells (ADSCs) on alendronate (Aln)-loaded polycarprolactone (PCL) nanofibrous scaffolds was evaluated by examining alkaline phosphatase (ALP) activity, calcium content, and expression differentiation genes in vitro. 10% Aln/PCL showed more ALP mineralization, osteocalcin osteopontin mRNA than the 1% or 5% scaffolds. capacity to regenerate new bone studied a rat calvarial defect model. New formation vivo radiography, micro-computed...