A5024731154- Foot and Ankle Surgery
- Tendon Structure and Treatment
- Sports injuries and prevention
- Orthopedic Surgery and Rehabilitation
- Knee injuries and reconstruction techniques
- Shoulder Injury and Treatment
- Lower Extremity Biomechanics and Pathologies
- Total Knee Arthroplasty Outcomes
- Gout, Hyperuricemia, Uric Acid
- Musculoskeletal pain and rehabilitation
- Peripheral Nerve Disorders
- Musculoskeletal synovial abnormalities and treatments
- Nail Diseases and Treatments
- Myofascial pain diagnosis and treatment
- Cerebral Palsy and Movement Disorders
- Healthcare and Venom Research
- Muscle activation and electromyography studies
- Cancer-related molecular mechanisms research
- Spine and Intervertebral Disc Pathology
- Bee Products Chemical Analysis
- Shoulder and Clavicle Injuries
- Sport Psychology and Performance
- Osteoarthritis Treatment and Mechanisms
- Case Reports on Hematomas
- Medical Imaging and Analysis
Huashan Hospital
2015-2025
Fudan University
2015-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2024
Shanghai University of Sport
2021-2024
University of Pittsburgh Medical Center
2022
National Natural Science Foundation of China
2021
Science and Technology Commission of Shanghai Municipality
2021
Zero to Three
2019
Background: The optimal graft choice of anterior cruciate ligament (ACL) reconstruction remains controversial. Purpose: To compare the outcomes, especially long-term cumulative failure rate, ACL using either synthetics with remnant preservation or hamstring autografts (4-strand semitendinosus and gracilis tendons). Study Design: Cohort study; Level evidence, 2. Methods: A total 133 patients who underwent (synthetics: n = 43; autografts: 90) between July 2004 December 2007 were included....
Background: The evidence supporting best practice guidelines in the field of cartilage repair ankle are based on both low quality and levels evidence. Therefore, an international consensus group experts was convened to collaboratively advance toward opinions available key topics within ankle. purpose this article is report statements “Conservative Management Biological Treatment Strategies” developed at 2017 International Consensus Meeting Cartilage Repair Ankle. Methods: Seventy-five...
Objective Increasing evidence suggests that impaired cartilage is a substantial risk factor for the progression from hyperuricaemia to gout. Since relationship between matrix protein and gout flares remains unclear, we investigated its role in monosodium urate (MSU) crystallisation following inflammation. Methods Briefly, screened synovial fluid gouty arthritis patients with injuries. After identifying correlation crystals molecules, conducted image analysis classification of crystal...
Anterior talofibular ligament (ATFL) injury is a commonly seen sports-related and major underlying pathology of chronic ankle instability. However, it difficult to accurately identify the ATFL.To investigate value ultrasound (US) examination in identifying ATFL injury.We evaluated 83 consecutive patients who underwent US for diagnosis subsequent arthroscopy. The arthroscopic findings were used as reference standard.Forty-four found have on accuracy detection was 95.2%, with sensitivity...
Gout is a common metabolic disease with growing burden, caused by monosodium urate (MSU) microcrystal deposition. In situ and chemical-specific histological identification of MSU crucial in the diagnosis management gout, yet it remains inaccessible for current methods. Methods: Stimulated Raman scattering (SRS) microscopy was utilized to image based on its fingerprint spectra. We first tested SRS capability gout differentiation power from pseudogout rat models acute arthritis, calcium...
Discoid lateral meniscus (DLM) is the most common congenital variant of meniscus, which prone to degeneration and lesions, often leads knee osteoarthritis. At present, there no consensus on clinical practice DLM, this expert guidelines DLM was developed approved by Chinese Society Sports Medicine according Delphi method. Among 32 statements drafted, 14 were excluded for redundant information, 18 achieved consensus. This focused definition, epidemiology, etiology, classification,...
The aim of this study was to quantitatively evaluate and characterize the dimension signal intensity anterior talofibular ligament (ATFL) using 3.0 T MRI in mechanical ankle instability group pre- postoperatively.A total 97 participants were recruited retrospectively study, including 56 with chronic (CAI group) 41 without (Control group). All subjects accepted preoperatively. Among CAI patients, 25 who modified Broström repair ATFL, underwent a scan at follow-up. ATFL (length width)...
Interleukin (IL)-37 is a natural suppressor of inflammation. Macrophages play an important role in acute gout flare by dominating the inflammation and spontaneous relief. We have reported that IL-37 could limit runaway gout. Here we focus on whether inhibits gouty altering macrophage functions, how it does so.Macrophage functions were evaluated terms phagocytosis, pyroptosis, polarization metabolism. Phagocytosis macrophages detected side scattering double-labelling induced nitrogen monoxide...
Background: Posterior cruciate ligament (PCL) injury is a relatively common musculoskeletal condition. However, there currently lack of consensus on decision-making, treatment and postoperative management for such injuries. Objectives: To use the modified Delphi method to reach expert PCL injury. Methods: A literature search PubMed, Cochrane Library, Embase, Web Science articles up 17 October 2024, support development recommendation statements. An Expert Panel 90 experienced clinicians from...
Background: Lateral ankle sprain is one of the most common injuries. Since structural and pathological differences in mechanical instability (MAI) functional (FAI) may not be same, it better to treat these as separate groups. The purpose this study was compare difference postural sway between MAI FAI patients with chronic (CAI). Methods: Twenty-six CAI 14 healthy control participants were included study. subdivided into (15 patients) (11 Patients who diagnosed lateral ligaments rupture by...
The treatment strategy for anterior talofibular ligament (ATFL) injury is usually determined by the ATFL remnant condition during surgery. Preoperative magnetic resonance imaging (MRI)-based signal intensity of remnant, represented signal/noise ratio (SNR) value, can reveal condition. Thus far, there a lack evidence regarding relationship between and functional outcomes.The purpose was to quantitatively evaluate whether MRI-based SNR value related outcomes after repair ankles with chronic...
RNA modifications in eukaryotic cells have emerged as an exciting but under-explored area recent years and are considered to be associated with many human diseases. While several studies been published relating m6A osteoarthritis (OA), we only limited knowledge of other kinds modifications. Our study investigated eight modifiers' specific roles OA including A-to-I, APA, m5C, m6A, m7G, mcm5s2U, Nm Ψ together their relationship immune infiltration.