- Total Knee Arthroplasty Outcomes
- Knee injuries and reconstruction techniques
- Orthopaedic implants and arthroplasty
- Osteoarthritis Treatment and Mechanisms
- Shoulder Injury and Treatment
- Sports injuries and prevention
- Orthopedic Infections and Treatments
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- Musculoskeletal synovial abnormalities and treatments
- Adhesion, Friction, and Surface Interactions
- Mast cells and histamine
- Shoulder and Clavicle Injuries
- Lower Extremity Biomechanics and Pathologies
- Hip disorders and treatments
- Mesenchymal stem cell research
- Periodontal Regeneration and Treatments
- Bone fractures and treatments
- Metal and Thin Film Mechanics
- Nerve Injury and Rehabilitation
- Hip and Femur Fractures
- Urticaria and Related Conditions
- Elbow and Forearm Trauma Treatment
- Extracellular vesicles in disease
- Heterotopic Ossification and Related Conditions
Marche Polytechnic University
2016-2025
Istituto Nazionale di Riposo e Cura per Anziani
2025
Istituti di Ricovero e Cura a Carattere Scientifico
2025
UMIT - Private Universität für Gesundheitswissenschaften, Medizinische Informatik und Technik
2024
Ospedali Riuniti di Ancona
2023-2024
Institute of Technology and Life Sciences
2023
Gelenkpunkt
2023
Tirol Kliniken
2023
Pain is the major symptom of osteoarthritis (OA) and an important factor in strategies to manage this disease. However, current standard care does not provide satisfactory pain relief for many patients. The pathophysiology OA complex, its presentation as a clinical syndrome associated with pathologies multiple joint tissues. Treatment options are generally classified pharmacologic, nonpharmacologic, surgical, complementary and/or alternative, typically used combination achieve optimal...
Adipose-derived MSCs (ASCs) and stromal vascular fraction (SVF) play an important role in regenerative medicine the treatment of osteoarthritis. ASCs extracted from lipoaspirates are a valuable cell source due to their abundance accessibility. retrieved aqueous digested lipoaspirate. The is known as SVF includes, ASCs, endothelial precursor cells (EPCs), (ECs), macrophages, smooth muscle cells, lymphocytes, pericytes, well pre-adipocytes. To date, two types techniques isolate have been...
The purpose of this study was to evaluate the differences in patient-reported functional outcomes, and graft failure revision ACL reconstruction using quadriceps tendon (QT), Hamstring (HT) bone-patellar tendon-bone (BPTB) autografts.Between 2010 2020, 97 patients who underwent (40 received a QT, 26 an HT 31 BPTB graft) met inclusion criteria. Pre-injury at 2-year postoperatively were evaluated for outcomes; Lysholm knee score, Tegner activity level VAS (visual analogue scale) pain; failure....
Anterior cruciate ligament rupture represents a career-threatening injury for professional soccer players.To analyze the pattern of injury, return to play (RTP), and performance consecutive series elite players after anterior reconstruction (ACLR).Case series; Level evidence, 4.We evaluated medical records 40 who underwent ACLR by single surgeon between September 2018 May 2022. Patient age, height, weight, body mass index, position, history, affected side, RTP time, minutes played per season...
The purpose of the present study was to assess, prospectively, safety, clinical effectiveness, and feasibility a single intra-articular injection microfragmented adipose tissue in different stages knee osteoarthritis (OA). included patients (aged 18−70 years), affected by OA (Kellgren−Lawrence I-IV). Unselected were evaluated before prospectively after 6, 12, 24 months from injection. Visual analog scale (VAS) injury outcome score (KOOS) used for evaluations. A total 202 eligible. mean...
High tibial valgus osteotomy (HTO) is a widely accepted procedure indicated for varus knee with symptomatic osteoarthritis of the medial compartment. However, there lack studies evaluating long term results this procedure. The primary aim study was to evaluate long-term survival opening wedge high isolated in compartment knee. secondary objective identify independent predictors conversion total arthroplasty (TKA).This retrospective 296 cases open HTOs performed at single center (level...
The purpose of this study was to evaluate the patient-reported outcomes, graft failure, quadriceps rupture and sports preference after arthroscopic ACL reconstruction in patients older than 50 years who underwent with a tendon (QT) autograft.Between 2010 2020, prospectively collected data were obtained from an institutional database. Patients primary minimum 2 follow-up included. undergoing revision or using other QT autograft, contralateral knee injury osteoarthritis (Ahlbäck stage higher)...
For elite professional soccer players and alpine skiers, injuries associated with anterior cruciate ligament (ACL) rupture, such as meniscal, cartilage, or collateral lesions, could result in a delayed return to sport compared isolated ACL injury.The purpose of the study was provide detailed description at time primary reconstruction skiers. It hypothesized that skiers would present different typical injury patterns due mechanisms.Cohort study; Level evidence, 3.Surgical reports arthroscopic...
The aim of this study was to investigate the presence synovial mast cells (MCs) in hip and knee tissue from osteoarthritis (OA) patients correlate them with clinical radiological data.Synovial obtained during arthroplasty 60 patients, 30 OA OA. Control without OA, 15 undergoing above-knee amputation receiving a replacement for fracture. Before surgery, radiographic findings were graded according Kellgren-Lawrence system data including pain (VAS) functional information (KOOS HOOS) collected....
Lateral extra-articular tenodesis (L.E.T.) have been proposed to reduce the tibia's anterior translation and internal rotation in concomitant Anterior cruciate ligament (A.C.L.) reconstruction. Recent studies show that addition of L.E.T. A.C.L. reconstruction results a statistically significant reduction graft failure. The purpose present study was evaluate clinical outcomes, complications, rate return preinjury sports level pediatric patients who underwent combined with at minimum 2-year...
Background: The incidence of anterior cruciate ligament (ACL) reconstruction is increasing, and quadriceps tendon (QT) autograft gaining popularity for both primary revision ACL reconstruction. Purpose: To evaluate the differences in patient-reported functional outcomes, concomitant injuries, graft failure versus surgery using QT autograft. Study Design: Cohort study; Level evidence, 3. Methods: A total 376 patients with 138 were retrospectively retrieved from a prospectively collected...
Abstract Purpose The primary objective of the present study was to evaluate if robotic‐assisted total knee arthroplasty (RO‐TKA) results in improved accuracy compared conventional TKA (CO‐TKA) with respect alignment and component positioning executing a preoperative digital plan. secondary compare patient‐reported outcome measures (PROMs) between two groups at 6 months follow‐up (FU). Methods Patients who underwent using concept constitutional were identified from database. Each patient...
Background: Posterior cruciate ligament (PCL) injury is a relatively common musculoskeletal condition. However, there currently lack of consensus on decision-making, treatment and postoperative management for such injuries. Objectives: To use the modified Delphi method to reach expert PCL injury. Methods: A literature search PubMed, Cochrane Library, Embase, Web Science articles up 17 October 2024, support development recommendation statements. An Expert Panel 90 experienced clinicians from...
A systematic review of the literature has been carried out to assess actual evidence use augmented reality in total knee arthroplasty (TKA). We then conducted a pilot clinical study examine accuracy Knee + navigation performing TKA. The present (AR) system allows surgeon view tibial and femur axis superimposed on surgical field through smart glasses. It provides real-time information during surgery intraoperative feedback.A PubMed, MEDLINE, Embase databases up May 2021 using keywords...
Lateral unicompartmental arthroplasty (UKA) and distal femoral osteotomy (DFO) represent surgical solutions in cases of valgus malalignment isolated lateral osteoarthritis (OA) the knee. The aim present study was to assess clinical results, complications, overall postoperative alignment a series DFO UKA with minimum 2-year follow-up active middle-aged patients.Patients knee OA who underwent opening-wedge or from 2017 2019 were reviewed. Each patient characterized by joint line convergence...
Meniscus tears are common in patients with primary or revision anterior cruciate ligament injuries. Given their important mechanical role the joint, efforts being made to repair as much of meniscus tear possible. However, all-inside might be challenging case an unstable due dislocation meniscal flap after deploying first anchor. Therefore, we describe details our technique that allows surgeon stabilize before repair, ensuring reduction throughout entire procedure.