A5100645557- Microbial Natural Products and Biosynthesis
- Genomics and Phylogenetic Studies
- Environmental Quality and Pollution
- Fungal Biology and Applications
- Radiomics and Machine Learning in Medical Imaging
- Gastric Cancer Management and Outcomes
- Horticultural and Viticultural Research
- Genetic diversity and population structure
- Prenatal Screening and Diagnostics
- Plant Molecular Biology Research
- SARS-CoV-2 and COVID-19 Research
- Heavy metals in environment
- Synthetic Organic Chemistry Methods
- Plant and animal studies
- Insect and Arachnid Ecology and Behavior
- Radiopharmaceutical Chemistry and Applications
- Metabolism and Genetic Disorders
- Soil Carbon and Nitrogen Dynamics
- Marine Sponges and Natural Products
- Phytochemicals and Antioxidant Activities
- Remote Sensing and Land Use
- Plant Reproductive Biology
- Fermentation and Sensory Analysis
- COVID-19 Clinical Research Studies
- Plant biochemistry and biosynthesis
First Affiliated Hospital of Zhengzhou University
2014-2025
Chinese Academy of Sciences
2016-2025
Qingdao University of Science and Technology
2019-2025
University of Chinese Academy of Sciences
2012-2025
Institute of Geographic Sciences and Natural Resources Research
2025
Nankai University
2024
Affiliated Hospital of Qingdao University
2023-2024
Microbiology Institute of Shaanxi
2015-2024
Institute of Microbiology
2015-2024
Southwest University
2020-2024
Chronic subdural hematoma (CSDH) is a trauma-associated condition commonly found in elderly patients. Surgery currently the treatment of choice, but it carries significant risk recurrence and death. Nonsurgical treatments remain limited ineffective. Our recent studies suggest that atorvastatin reduces hematomas improves clinical outcomes patients with CSDH.To investigate safety therapeutic efficacy to nonsurgically treat CSDH.The Effect Atorvastatin on Subdural Hematoma (ATOCH) randomized,...
Abstract While soybean ( Glycine max L.) provides the most important source of vegetable oil and protein, it is sensitive to salinity, which seriously endangers yield quality during production. The application Plant Growth‐Promoting Rhizobacteria (PGPR) improve salt tolerance for plant currently gaining increasing attention. Streptomycetes are a major group PGPR. However, date, few streptomycetes has been successfully developed applied promote in soybean. Here, we discovered novel PGPR...
Red soils, which are widely distributed in tropical and subtropical regions of southern China, characterized by low organic carbon, high content iron oxides, acidity and, hence, likely to be ideal habitats for acidophilic actinomycetes. However, the diversity biosynthetic potential actinomycetes such underexplored. Here, a total 600 actinomycete strains were isolated from red soils collected Jiangxi Province southeast China. 16S rRNA gene sequence analysis revealed isolates, into 26 genera,...
Macrotermitinae (fungus-cultivating termites) are major decomposers in tropical and subtropical areas of Asia Africa. They have specifically evolved mutualistic associations with both a Termitomyces fungi on the nest gut microbiota, providing model system for probing host-microbe interactions. Yet symbiotic roles microbes residing its feeding caste remain largely undefined. Here, by pyrosequencing whole metagenome adult workers fungus-cultivating termite (Odontotermes yunnanensis), we showed...
The continuous emergence of SARS-CoV-2 variants highlights the need developing vaccines with broad protection. Here, according to immune-escape capability and evolutionary convergence, representative strains carrying hotspot mutations were selected. Then, guided by structural computational analyses, we present a mutation-integrated trimeric form spike receptor-binding domain (mutI-tri-RBD) as broadly protective vaccine candidate, which combined heterologous RBDs from different into hybrid...
The increased coronavirus disease 2019 (COVID-19) breakthrough cases pose the need of booster vaccination. We conducted a randomised, double-blinded, controlled, phase 2 trial to assess immunogenicity and safety heterologous prime-boost vaccination with an inactivated COVID-19 vaccine (BBIBP-CorV) followed by recombinant protein-based (NVSI-06-07), using homologous boost BBIBP-CorV as control. Three groups healthy adults (600 individuals per group) who had completed two-dose vaccinations 1-3...
Abstract Microorganisms living in soil maintain intricate interactions among themselves, forming the microbiota that influences rhizosphere microbiome and plant growth. However, mechanisms underlying microbial remain unclear. Streptomyces Mesorhizobium are commonly found serve as growth-promoting rhizobacteria (PGPR). Here, we identified an unprecedented interaction between colonies of red-soil-derived sp. FXJ1.4098 BAC0120 referred to it “proximity-based defensive mutualism (PBDM).” We...
ABSTRACT Fungus-growing termites play an important role in lignocellulose degradation and carbon mineralization tropical subtropical regions, but the potentiality of their gut microbiota has long been neglected. The high quality quantity intestinal microbial DNA are indispensable for exploring new cellulose genes from by function-based screening. Here, using a refined extraction method followed multiple-displacement amplification (MDA), fosmid library was constructed total isolated termite...
Background Hypertension is a significant global public health problem and recognized as an important risk factor for cardiovascular diseases. This study was designed to assess the current prevalence of hypertension explore factors associated with by urban rural status guide prevention control in Jilin province. Methods A multi-stage stratified random cluster sampling method used obtain data on hypertension, which investigated physical examination face-to-face questionnaire July 2014-December...
Hepatocellular carcinoma (HCC) is highly resistant to traditional chemotherapeutic approaches, which causes difficulty in the development of effective drugs for treatment HCC. Berberine, a major ingredient Rhizoma coptidis , natural alkaloid used Chinese medicine. Berberine exhibits potent antitumor activity against HCC due its high efficiency and low toxicity. In present study, we found that berberine sensitized HepG cells NF-κB-mediated apoptosis. exhibited significant antiproliferation...
Summary Actinobacteria produce a variety of secondary metabolites that can influence the survival or behaviour other organisms. The understanding ecological roles actinobacteria has significantly improved in past decades, but systematic insight into interactions between and microbes nature is warranted. Here, we studied pairwise effects on isolated from red soils under different nutritional conditions. We found neutral dominated interactions, accounting for 68.1% eutrophic conditions higher...
Background: Home beauty devices for facial rejuvenation utilizing technologies such as radiofrequency, microcurrent, and light emitting diode have gained widespread attention due to their claimed ability improve skin tightness elasticity, making them popular among consumers. However, there is controversy within the industry regarding effectiveness safety of these devices. Objective: This study aims verify home in treating aging based on relevant efficacy evaluation indicators. Methods: A...
Abstract Arbuscular mycorrhizal fungi (AMF) are crucial symbiotic partners for plant nitrogen (N) acquisition and sensitive to exogenous N inputs. However, the AMF mycelial respiration ( R ) has always been overlooked in previous studies, extent which different levels of input can induce changes remains elusive. Based on a long‐term field experiment with gradient addition rates (0, 2, 4, 8, 16, 32 g m −2 year −1 an alpine meadow Qinghai–Tibetan Plateau, we investigated response enrichment...
Abstract Colorado potato beetle (CPB), Leptinotarsa decemlineata (Say) (Coleoptera: Chrysomelidae), is a global destructive pest of potato, Solanum tuberosum L. (Solanaceae). It also an important quarantine in China, but its dispersal history, occurrence, and economic impact China have not yet been reported. We determined the current distribution CPB reconstructed routes. investigated density 2006, 2007, 2009, 2010, estimated China. In 1993, was first detected Xinjiang subsequently spread...
This study examined the value of a novel 1-step labeled integrin α<sub>v</sub>β<sub>3</sub>–targeting <sup>18</sup>F-AlF-NOTA-PRGD2 (denoted as <sup>18</sup>F-RGD) scan in assessing sensitivity to concurrent chemoradiotherapy (CCRT) patients with newly diagnosed glioblastoma multiforme (GBM). <b>Methods:</b> Twenty-five GBM were enrolled this 3–5 wk after surgical resection. All participants investigated <sup>18</sup>F-RGD PET/CT on baseline (T1) and at third week (T2) start CCRT. Tumor...
As an important signal molecule, salicylic acid (SA) improves plant tolerance to aluminum (Al) stress. The objective of this study was investigate the effects exogenous SA application on dynamics endogenous and reactive oxygen species in soybean (Glycine max L.) exposed Al roots seedlings were a combination AlCl3 (30 μM) (10 μM)/PAC (100 μM, paclobutrazol, biosynthesis inhibitor) for 3, 6, 9 12 h. stress induced increase concentration time-dependent manner, also verified by up-regulated...