A5016774167- Shoulder Injury and Treatment
- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- Total Knee Arthroplasty Outcomes
- Tendon Structure and Treatment
- Orthopedic Surgery and Rehabilitation
- Periodontal Regeneration and Treatments
- Orthopaedic implants and arthroplasty
- Bone fractures and treatments
- Shoulder and Clavicle Injuries
- Sports injuries and prevention
- Lower Extremity Biomechanics and Pathologies
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Hip and Femur Fractures
- Elbow and Forearm Trauma Treatment
- Musculoskeletal synovial abnormalities and treatments
- Connective tissue disorders research
- Mesenchymal stem cell research
- Foot and Ankle Surgery
- Spine and Intervertebral Disc Pathology
- Pelvic and Acetabular Injuries
- Nerve Injury and Rehabilitation
- Bone Tissue Engineering Materials
- Reconstructive Surgery and Microvascular Techniques
Marche Polytechnic University
2016-2025
Istituto Nazionale di Riposo e Cura per Anziani
2024-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2024-2025
Sapienza University of Rome
2009-2024
Ospedale San Luigi Gonzaga
2024
University of Turin
2024
University of Sannio
2022-2024
Ospedali Riuniti di Ancona
2004-2023
University of Ferrara
2023
Azienda Ospedaliero Universitaria Ospedali Riuniti
2021-2023
We performed intra-articular reconstruction of the anterior cruciate ligament (ACL) with semitendinosus tendon placed in 2 mm diameter tunnels 21 skeletally immature rabbits. The operation caused 11% damage to physis femur on frontal plane and 3% its cross-sectional area but no alteration growth or axial deviation bone resulted. In tibia, 12% 4% area. Two tibiae developed valgus deformities one was shortened. Histological examination showed areas epiphysiodesis. There abnormality...
Different single-stage surgical approaches are currently under evaluation to repair cartilage focal lesions. To date, only little is known on even short-term clinical follow-up and almost no knowledge exists histological results of such treatments. The present paper aims analyze the collagen-covered microfracture bone marrow concentrate (C-CMBMC) technique in treatment condylar lesions knee articular cartilage.Nine patients with were consecutively treated arthroscopic microfractures (MFX)...
Pain is the major symptom of osteoarthritis (OA) and an important factor in strategies to manage this disease. However, current standard care does not provide satisfactory pain relief for many patients. The pathophysiology OA complex, its presentation as a clinical syndrome associated with pathologies multiple joint tissues. Treatment options are generally classified pharmacologic, nonpharmacologic, surgical, complementary and/or alternative, typically used combination achieve optimal...
Chondral articular defects are a key concern in orthopaedic surgery. To overcome the disadvantages of autologous chondrocyte implantation (ACI) and to improve outcomes matrix-induced chondrogenesis (AMIC), latter technique is currently augmented with bone marrow concentrate injected under or seeded onto scaffold. However, date, only little known about histological either AMIC associated concentrate. This study aimed evaluate quality repair tissue obtained from biopsies harvested during...
The objective of this study was to evaluate the safety and effect platelet-rich plasma (PRP) intra-articular injections obtained from blood donors (homologous PRP) on elderly patients with early or moderate knee osteoarthritis (OA) who are not candidates for autologous PRP treatment.A total 60 symptomatic patients, aged 65-86 years, affected by hematologic disorders OA, were treated 5 ml homologous every 14 days a three injections. Clinical evaluations before treatment, after 2 6 months...
Adipose-derived MSCs (ASCs) and stromal vascular fraction (SVF) play an important role in regenerative medicine the treatment of osteoarthritis. ASCs extracted from lipoaspirates are a valuable cell source due to their abundance accessibility. retrieved aqueous digested lipoaspirate. The is known as SVF includes, ASCs, endothelial precursor cells (EPCs), (ECs), macrophages, smooth muscle cells, lymphocytes, pericytes, well pre-adipocytes. To date, two types techniques isolate have been...
In hip arthroplasty, preoperative planning is fundamental to reaching a successful surgery. Nowadays, several software tools for computed tomography (CT) image processing are available. However, research studies comparing segmentation surgery patients affected by osteoarthritic diseases or osteoporotic fractures still lacking. The present work compares three different from the geometric, dimensional, and usability perspectives identify best three-dimensional (3D) modelling tool...
Twenty-seven adolescents with anterior knee pain or without patellar instability were studied by comput erized tomography to detect patellofemoral malalign ment. The examination was performed and quadriceps contraction the flexed 15°. Con gruence angle, tilt sulcus trochlear depth measured. This investigation showed well-known types of mal alignment relaxed (tilted, lateralized, tilted patella) and, in 52% cases, re vealed changes type severity (in 41 %, lateralization tilting mark edly more...
Purpose – The purpose of this study is to show how selective laser sintering (SLS) manufacturing bioresorbable scaffolds used for applications in bone tissue engineering. Design/methodology/approach Polycaprolactone (PCL) were computationally designed and then fabricated via SLS cartilage repair. Findings Preliminary biocompatibility data acquired using human mesenchymal stem cells (hMSCs) assuring a satisfactory scaffold colonization by hMSCs. Originality/value A promising procedure...