Peng Zhang

ORCID: 0000-0001-7277-9429
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About
Contact & Profiles
Research Areas
  • Tendon Structure and Treatment
  • Knee injuries and reconstruction techniques
  • Spinal Fractures and Fixation Techniques
  • Shoulder Injury and Treatment
  • Osteoarthritis Treatment and Mechanisms
  • Spine and Intervertebral Disc Pathology
  • Bladder and Urothelial Cancer Treatments
  • Cervical and Thoracic Myelopathy
  • Hip and Femur Fractures
  • Total Knee Arthroplasty Outcomes
  • Bone Tumor Diagnosis and Treatments
  • Orthopedic Infections and Treatments
  • Urinary and Genital Oncology Studies
  • Orthopedic Surgery and Rehabilitation
  • Sarcoma Diagnosis and Treatment
  • Orthopaedic implants and arthroplasty
  • Anesthesia and Pain Management
  • Foot and Ankle Surgery
  • Pelvic and Acetabular Injuries
  • Bone fractures and treatments
  • Nutrition and Health in Aging
  • Scoliosis diagnosis and treatment
  • Anesthesia and Sedative Agents
  • Bone and Joint Diseases
  • Sports injuries and prevention

Children's Hospital of Fudan University
2021-2025

Huashan Hospital
2006-2024

Fudan University
2015-2024

Henan Cancer Hospital
2013-2024

China Meteorological Administration
2024

Union Hospital
2008-2024

Chongqing University of Science and Technology
2024

Shandong Provincial Hospital
2020-2024

Shandong First Medical University
2021-2024

Hubei University of Arts and Science
2020-2024

Polyethylene terephthalate (PET) artificial ligaments, renowned for their superior mechanical properties, have been extensively adopted in anterior cruciate ligament (ACL) reconstruction surgeries. However, the inherent bio-inertness of PET introduces formidable barriers to graft-bone integration, a critical aspect rehabilitation. Previous interventions, ranging from surface roughening chemical modifications, aimed address this challenge; however, consistently effective techniques inducing...

10.1021/acsami.3c14904 article EN ACS Applied Materials & Interfaces 2024-03-21

Despite the best current treatments, intra-articular fractures commonly cause posttraumatic osteoarthritis. In this disorder, death and dysfunction of chondrocytes associated with acute cartilage injury presumably plays an important role in triggering pathomechanical cascade that eventually leads to whole-joint degeneration. Information regarding cell-level injury, particularly at whole-organ level actual human joints, has been lacking. study, distribution progression fracture-associated...

10.2106/jbjs.i.01777 article EN Journal of Bone and Joint Surgery 2011-03-01

Background: The optimal graft choice of anterior cruciate ligament (ACL) reconstruction remains controversial. Purpose: To compare the outcomes, especially long-term cumulative failure rate, ACL using either synthetics with remnant preservation or hamstring autografts (4-strand semitendinosus and gracilis tendons). Study Design: Cohort study; Level evidence, 2. Methods: A total 133 patients who underwent (synthetics: n = 43; autografts: 90) between July 2004 December 2007 were included....

10.1177/0363546517721692 article EN The American Journal of Sports Medicine 2017-09-11

The Lancet Commission on Global Surgery established the Three Delays framework, categorising delays in accessing timely surgical care into seeking (First Delay), reaching (Second and receiving (Third Delay). Globally, knowledge gaps regarding for fracture care, lack of large prospective studies informed rationale our international observational study. We investigated hospital admission as a surrogate explored factors associated with delayed admission.

10.1016/s2214-109x(20)30067-x article EN cc-by The Lancet Global Health 2020-04-27

Surgical repair around the bone-tendon insertion (BTI) may involve bone-to-bone (BB), bone-to-tendon (BT), or tendon-to-tendon (TT) reattachment with varying healing outcome.The of Achilles tendon-calcaneus (ATC) by homogeneous tissue (BB TT) would heal faster, respect to tensile properties at complex, than those heterogeneous tissues (BT) over time.Controlled laboratory study.Forty-seven adolescent male Chinese goats were divided into BB, BT, and TT groups. Osteotomy calcaneus, tendon...

10.1177/0363546515576904 article EN The American Journal of Sports Medicine 2015-03-30

Either an anterior approach or a posterior approach, which aims to decompress the spinal cord and restore sagittal alignment, has been adopted treat multilevel cervical degenerative myelopathy (CDM) associated with kyphosis. However, there is controversy on optimal surgical strategy for treatment of CDM kyphotic deformity because complications each approach.The purpose this study was investigate efficacy enlarged laminectomy (removing inside edge facet joints decompressing nerve foramina)...

10.1016/j.spinee.2013.06.017 article EN cc-by-nc-nd The Spine Journal 2013-08-21

Massive rotator cuff tears (MRCTs) are difficult to repair because of the retraction and poor mobility torn tendons. In current study, co-electrospun dual nano-scaffolds poly(lactic-co-glycolic acid)/collagen I-polycaprolactone/nanohydroxyapatite (PLGA/Col-PCL/nHA) were fabricated used bridge MRCTs infraspinatus tendons in a rabbit model. PLGA-PCL served as control. The PLGA or PLGA/Col sides scaffolds connected tendon stumps. PCL PCL/nHA side was inserted into bone tunnel at insertion...

10.1039/c6tb01674j article EN Journal of Materials Chemistry B 2016-01-01

The choice of grafts for anterior cruciate ligament (ACL) reconstruction is a critical issue in sports medicine. Previous studies have revealed that scaffolds prepared from single material could not achieve complete integration between the graft and autogenous bone tunnel. To solve this problem, we hypothesize combining degradable with nondegradable can produce novel hybrid advantages both types scaffolds. In study, morphogenetic protein 7 (BMP-7)-loaded polycaprolactone (PCL) nanofibrous...

10.1039/c9bm01703h article EN Biomaterials Science 2019-12-04

Background: The concrete anatomy and functional characteristics of the subtalar ligaments have been a matter debate that some believe has hampered progress clinical ligament reconstruction. Methods: In 32 fresh-frozen cadaver feet, course inferior extensor retinaculum (IER) other was carefully measured photographed both from portal tarsal sinus posterior view. Results: IER inserted inside canal by means 3 roots: lateral, an intermediate, medial one. These roots, along with canal, divided...

10.1177/1071100713500653 article EN Foot & Ankle International 2013-08-02

Abstract: Hamstring tendon autograft is a routine graft for anterior cruciate ligament (ACL) reconstruction. However, ways of improving the healing between and bone often overlooked in clinical practice. This issue can be addressed by using biomimetic scaffold. Herein, nanofiber membrane polycaprolactone/nanohydroxyapatite/collagen (PCL/nHAp/Col) fabricated that mimics composition native tissue promoting tendon–bone healing. has good cytocompatibility, allowing osteoblast cell adhesion...

10.2147/ijn.s92099 article EN cc-by-nc International Journal of Nanomedicine 2015-12-01

Accurate detection of cartilage injuries is critical for their proper treatment because these lack the self-healing ability and lead to joint dysfunction. However, low longitudinal T1 relaxivity (

10.1016/j.bioactmat.2020.05.009 article EN cc-by-nc-nd Bioactive Materials 2020-06-21

As a common musculoskeletal disorder, frozen shoulder is characterized by thickened joint capsule and limited range of motion, affecting 2-5% the general population more than 20% patients with diabetes mellitus. Pathologically, fibrosis resulting from fibroblast activation key event. The activated fibroblasts are proliferative contractive, producing excessive collagen. Albeit high prevalence, effective anti-fibrosis modalities, especially fibroblast-targeting therapies, still lacking. In...

10.1186/s12951-024-02403-w article EN cc-by Journal of Nanobiotechnology 2024-04-10
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