A5100443491- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Radiomics and Machine Learning in Medical Imaging
- Medical Imaging and Analysis
- Osteoarthritis Treatment and Mechanisms
- Knee injuries and reconstruction techniques
- Lower Extremity Biomechanics and Pathologies
- Shoulder Injury and Treatment
- Foot and Ankle Surgery
- Tendon Structure and Treatment
- MRI in cancer diagnosis
- Pelvic and Acetabular Injuries
- Sarcoma Diagnosis and Treatment
- Kawasaki Disease and Coronary Complications
- Bone health and osteoporosis research
- Hernia repair and management
- Advanced MRI Techniques and Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Total Knee Arthroplasty Outcomes
- Inflammasome and immune disorders
- Shoulder and Clavicle Injuries
- Colorectal Cancer Surgical Treatments
- Medical Imaging Techniques and Applications
- Bone Tumor Diagnosis and Treatments
- Spondyloarthritis Studies and Treatments
Huashan Hospital
2015-2025
Fudan University
2015-2025
Nanjing University of Chinese Medicine
2022-2025
Hubei University of Chinese Medicine
2025
Integrated Chinese Medicine (China)
2025
National Health and Family Planning Commission
2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2020-2024
Shanghai Stomatological Hospital
2021-2024
Guangxi Medical University
2024
Cell Technology (China)
2024
ABSTRACT Opportunistic screening for osteoporosis can be performed using low-dose computed tomography (LDCT) imaging obtained other clinical indications. In this study we explored the CT-derived bone mineral density (BMD) and prevalence of from thoracic LDCT in a large population cohort Chinese men women. A total 69,095 adults (40,733 28,362 women) received scan purpose lung cancer between 2018 2019, data were analysis China Biobank Project, prospective nationwide multicenter study. Lumbar...
Background: Currently, there is an ongoing debate regarding the optimal graft choice between autograft and allograft tendons in reconstruction of anterior cruciate ligament (ACL). It has been reported that have a slower onset rate revascularization compared with tendons. Hypothesis: Allograft might inferior maturity ACL at 2 years postoperatively. Study Design: Cohort study; Level evidence, 3. Methods: A total 52 participants were recruited this study, including 30 using 22 All them had...
Homocysteine (Hcy) has been shown to have a neurotoxic effect on ischemic brain cells; however, the underlying mechanisms remain incompletely understood. Here, we examined whether Hcy treatment influences mitochondria injury, oxidative stress, and mitochondrial STAT3 (mitoStat3) expression in rat brain. Our results demonstrated that aggravated damage of ultrastructure cortex dentate gyrus region hippocampus after focal cerebral ischemia. An elevated level was also accompanied by significant...
Background: Postoperatively, signal changes of the reconstructed anterior cruciate ligament (ACL) graft on magnetic resonance imaging (MRI) images commonly occurs, which may be a cause for concern. The intensity are usually expressed by signal/noise quotient (SNQ) value, representing maturity. To date, little is known about factors influencing SNQ value ACL graft. Purpose: evaluate and associated after reconstruction. Study Design: Case series; Level evidence, 4. Methods: Male patients who...
Myocardial ischemia-reperfusion is the leading cause for events of cardiovascular disease, and considered as a major contributor to morbidity mortality associated with coronary occlusion. The myocardial damage caused by ischemia‑reperfusion injury constitutes primary pathological manifestation artery disease. It results from interaction between substances that accumulate during ischemia those are delivered on reperfusion. level this can range small insult resulting in limited large...
Valvular heart disease (VHD) is caused by either damage or defect in one of the four valves, aortic, mitral, tricuspid pulmonary. Defects these valves can be congenital acquired. Age, gender, tobacco use, hypercholesterolemia, hypertension, and type II diabetes contribute to risk disease. VHD an escalating health issue with a prevalence 2.5% United States alone. Considering likely increase aging population worldwide, incidence acquired expected increase. Technological advances are...
BackgroundAlthough abdominal adiposity is associated with an altered cardiometabolic risk profile, the specific contribution of adipose tissue distribution remains not fully understood. Computed tomography (CT) a well-established and precise method to measure distribution. The present study investigated assessed by CT in large-scale Chinese population.MethodA total 59,429 adults who underwent low dose chest for lung cancer screening at one 13 health checkup centers throughout China were...
Quantitative magnetic resonance imaging (MRI) has the function of noninvasive quantitative evaluation, providing unique advantages in intervertebral disc degeneration (IDD) assessment. Although studies exploring field for domestic and international scholars are increasingly being published, there is a lack systematic scientific measurement clinical analysis literature this field.Articles published from respective database establishment to September 30, 2022, were obtained Web Science core...
Heart failure (HF) is a global health crisis with an increasing prevalence, emphasizing the urgent need for effective diagnostic and monitoring strategies. B-type natriuretic peptide (BNP), sensitive specific biomarker, has revolutionized HF management by enabling early detection, risk stratification, treatment guidance. However, conventional methods BNP detection face limitations in sensitivity, specificity, real-time capabilities. Electrochemical biosensors have emerged as promising...
Background GRAPPATINI is capable of originating synthetic T2 images (T2 synth ) and maps in one magnetic resonance imaging (MRI) scan. Purpose To evaluate GRAPPATINI's performance providing simultaneous morphological assessment repaired rotator cuffs (RC) using quantitative evaluation the postoperative clinical outcomes on maps. Material Methods A total 45 individuals after repair surgery for at least 2 years were prospectively examined with MRI. Clinical scores also collected. Image quality...
This study investigates the correlation between magnetic resonance diffusion tensor imaging (DTI) parameters and biochemical composition in degenerative intervertebral disc nucleus pulposus tissue, offering a potential reference for clinical diagnosis efficacy evaluation of degeneration. Human lumbar tissue samples were collected via full endoscopic minimally invasive surgery. DTI was employed to quantitatively measure fractional anisotropy (FA) apparent coefficient (ADC) values pulposus,...
Monocyte-derived dendritic cells (moDCs) play important roles in the pathogenesis of systemic lupus erythematosus (SLE). Aberrant expression long noncoding RNAs (lncRNAs) could affect function moDCs. The aim this study was to explore lncRNA profile moDCs SLE patients provide new insights into SLE. LncRNA and mRNA microarrays were performed identify differentially expressed lncRNAs mRNAs compared with normal controls. Bioinformatics analysis also performed. Quantitative polymerase chain...
Accurate detection of cartilage injuries is critical for their proper treatment because these lack the self-healing ability and lead to joint dysfunction. However, low longitudinal T1 relaxivity (
Background: Associated meniscal injury is well recognized at anterior cruciate ligament (ACL) reconstruction, and it a known risk factor for osteoarthritis. Purpose: To evaluate characterize the postoperative appearance of articular cartilage after different treatment in ACL-reconstructed knees using T2 relaxation time evaluation on MRI. Study Design: Cohort study; Level evidence, 3. Methods: A total 62 consecutive patients who under ACL reconstruction were recruited this study, including 23...