A5100382126- Angiogenesis and VEGF in Cancer
- Bone Metabolism and Diseases
- Streptococcal Infections and Treatments
- Acute Myocardial Infarction Research
- Infective Endocarditis Diagnosis and Management
- Zebrafish Biomedical Research Applications
- Apelin-related biomedical research
- Metabolomics and Mass Spectrometry Studies
- Cardiac Ischemia and Reperfusion
- ATP Synthase and ATPases Research
- Ginseng Biological Effects and Applications
- Cardiac electrophysiology and arrhythmias
- Natural product bioactivities and synthesis
- Cancer, Hypoxia, and Metabolism
- Cardiac Fibrosis and Remodeling
- Heart Failure Treatment and Management
- Mitochondrial Function and Pathology
- Traditional Chinese Medicine Analysis
- Fuel Cells and Related Materials
- Trace Elements in Health
- Bacterial Identification and Susceptibility Testing
- Phytochemical Studies and Bioactivities
- Bone health and treatments
- Colorectal Cancer Treatments and Studies
- Proteoglycans and glycosaminoglycans research
Jinzhou Medical University
2017-2024
Southern Medical University
2023
South China University of Technology
2023
People’s Hospital of Rizhao
2021
Beijing University of Chinese Medicine
2017-2019
Tianjin Medical University
2014
Heart failure (HF) is a global health crisis with an increasing prevalence, emphasizing the urgent need for effective diagnostic and monitoring strategies. B-type natriuretic peptide (BNP), sensitive specific biomarker, has revolutionized HF management by enabling early detection, risk stratification, treatment guidance. However, conventional methods BNP detection face limitations in sensitivity, specificity, real-time capabilities. Electrochemical biosensors have emerged as promising...
Velvet antler (VA) is a precious traditional Chinese medicine that capable of repeated regeneration. Based on the theory coordination heart and kidneys, VA has been employed to treat diseases, including ischemic disease, failure, arrhythmia. We examined effects proteins primary cardiac microvascular endothelial cells (CMECs) were subjected ischemia-hypoxia (IH) investigate their mechanism action in treatment disease. (VA-pro) extracted with water as solvent, ultrasonic wave method,...
Objective: This investigation examined the effect of velvet antler (VA) on endothelial progenitor cells (EPCs) and associated effects to promote angiogenesis repair vascular injury in rats with myocardial infarction (MI). Methods: VA was analyzed by liquid chromatography-mass spectrometry. Male Sprague Dawley were randomly divided into four groups: sham, MI, VA, + DAPT (gamma-secretase inhibitor IX, a specific blocker Notch signaling pathway) group. The underwent ligation left anterior...
Although diagnosis and treatment of gastric cancer have improved, the prognosis patients remains poor. The majority should be treated with chemotherapy or other follow-up treatment. However, drug resistance heterogeneity tumor itself lead to differences sensitivity drugs for different patients. Therefore, it is mandatory develop better methods cancer. Calycosin has been used in several types cells. Cisplatin, 5-fluorouracil (5-FU), adriamycin (ADM) are most widely chemotherapy, they improve...
Lu Rong, velvet antler (VA), is a traditional Chinese medicine, which used as food supplement and therapeutic drug in China, Japan, Russia, New Zealand Southeast Asia. The regenerative characteristics of VA have resulted great research interest, particularly regarding the fields organ grafting stem cell differentiation. Various proteomic studies verified that proteins act primary bioactive components VA. present study aimed to investigate if (VA‑pro) influence endothelial progenitor (EPC)...
Objective: Velvet antler (VA; cornu cervi pantotrichum), a well-known traditional Chinese medicine, has been shown to exert cardioprotective effects. The purpose of this study was investigate the effect VA on heart failure (HF) caused by ischemia-reperfusion, and explore its possible mechanism from regulation sarcoplasmic/endoplasmic reticulum Ca 2+ -ATPase 2 alpha (SERCA2a). Methods: A rat model HF established ligating left anterior descending coronary artery male Sprague–Dawley rats ( n =...
SangQiQingXuan (SQQX) decoction is a pharmaceutical preparation exerting good therapeutic efficacy on high blood pressure (BP) and has widely been accepted in primarily hypertensive patients as herbal formula prescribed by Professor Li Huang from China‐Japan Friendship Hospital according to her 30‐year clinical experience. A previous study showed that SQQX could reduce BP decreasing levels of many inflammatory factors such transforming growth factor beta (TGF β ) elevating peroxisome...
Objective To investigate the effect of naringin on bone healing osteoporotic fracture in ovariectomized rats and possible mechanism. Methods Sixty female SD rats, 3 months age, were oophorectomized bilaterally before establishment model. Two after operation, transverse right tibia was induced. The assigned to control group, group estrogen according random number table, with 20 per group. Rats groups treated 100 mg/kg day 17-β-estradiol 22.5 μg/kg respectively. Instead, isotonic saline...
Introduction Next-generation sequencing of microbial cell free DNA (mcfDNA-seq) has emerged as a promising diagnostic method for blood stream infection (BSI) and offers the potential to detect pathogens before culture. However, its application is limited by lack clinical validation. Methods We conducted sequential mcfDNA-seq on samples from ICU participants at high risk BSI due pneumonia, or intravascular catheterization; explored whether could diagnose in advance culture positivity. Blood...