A5009850665- Diabetes, Cardiovascular Risks, and Lipoproteins
- Adipokines, Inflammation, and Metabolic Diseases
- Cardiovascular Disease and Adiposity
- Lipoproteins and Cardiovascular Health
- Lipid metabolism and disorders
- Adipose Tissue and Metabolism
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Obesity, Physical Activity, Diet
- Cardiovascular and exercise physiology
- Health and Lifestyle Studies
- Nutritional Studies and Diet
- Diet, Metabolism, and Disease
- Pharmacology and Obesity Treatment
- Cardiovascular Function and Risk Factors
- Cardiovascular Health and Risk Factors
- Cancer, Lipids, and Metabolism
- Vitamin D Research Studies
- Metabolism, Diabetes, and Cancer
- Growth Hormone and Insulin-like Growth Factors
- Nutrition and Health in Aging
- Physical Activity and Health
- Obesity and Health Practices
- Regulation of Appetite and Obesity
- Cannabis and Cannabinoid Research
Université Laval
2015-2025
Institut Universitaire de Cardiologie et de Pneumologie de Québec
2013-2024
Montreal Heart Institute
2001-2020
Quebec Research and Development Centre
2016
Lung Institute
2016
Cegep de Sainte Foy
2002-2014
Medical Research Council
2010
Amsterdam UMC Location University of Amsterdam
2010
University of Amsterdam
2010
University of Cambridge
2010
Background —The present study tested the hypothesis that simple variables, such as waist circumference and fasting plasma triglyceride (TG) concentrations, could be used screening tools for identification of men characterized by a metabolic triad nontraditional risk factors (elevated insulin apolipoprotein [apo] B small, dense LDL particles). Methods Results —Results (study 1) conducted on 185 healthy indicate large proportion (>80%) with values ≥90 cm elevated TG levels (≥2.0 mmol/L)...
Abstract —Recent studies have suggested that elevated plasma C-reactive protein (CRP) levels are associated with the features of insulin resistance syndrome. In present study, we examined contribution body composition measured by hydrostatic weighing and abdominal adipose tissue (AT) accumulation assessed computed tomography to variation in CRP atherogenic dyslipidemia syndrome a sample 159 men, aged 22 63 years, covering wide range adiposity (body mass index values from 21 41 kg/m 2 )....
<h3>Background</h3> Total cholesterol (TC)/high-density lipoprotein (HDL-C) and low-density (LDL-C)/HDL-C ratios are used to predict ischemic heart disease risk. There is, however, no consensus on which of these 2 indices is superior. The objective the present study was evidence that LDL-C/HDL-C ratio may underestimate risk in overweight hyperinsulinemic patients with high triglyceride (TG)–low HDL-C dyslipidemia. <h3>Methods</h3> A total 2103 middle-aged men whom measurements metabolic...
The present study examined the associations between a major adipokine, adiponectin, and adiposity indices as well metabolic risk variables in sample of 190 untreated asymptomatic men. Anthropometric measurements complete fasting plasma lipoprotein lipid profile were obtained, subjects underwent an oral glucose tolerance test. Fasting adiponectin concentrations determined by ELISA. Although all adipose tissue (AT) distribution negatively correlated with levels (−0.14 ≤ r −0.32; P &lt;...
OBJECTIVE: Age-related differences in body fat and, more specifically, the accumulation of abdominal visceral adipose tissue (AT) were examined as potential covariates age-related difference metabolic profile predictive cardiovascular disease (CVD) risk observed young, compared with middle-aged, premenopausal women. RESEARCH DESIGN AND METHODS: Body composition, AT distribution, plasma lipoprotein-lipid levels, glucose tolerance, and insulin concentrations assessed a sample 122 young women...
Rimonabant, the first selective cannabinoid type 1 (CB1) receptor antagonist, improves cardiometabolic risk factors in overweight/obese patients. ADAGIO-Lipids assessed effect of rimonabant on and intraabdominal liver fat.803 abdominally obese patients with atherogenic dyslipidemia (increased triglycerides [TG] or reduced high-density lipoprotein-cholesterol [HDL-C]) were randomized to placebo 20 mg/d for year. HDL-C TG coprimary end points. Intraabdominal (visceral) fat measured by computed...
Reduced plasma HDL cholesterol concentration has been associated with an increased risk of coronary heart disease. However, a low is usually not observed as isolated disorder because this condition often accompanied by additional metabolic alterations. The objective study was to document the relevance assessing particle size another feature atherogenic dyslipidemia found among subjects visceral obesity and insulin resistance. For that purpose, average computed calculating integrated using...
Hyperinsulinemia has been suggested to be involved in the etiology of obesity-associated hypertension. The objective present study was quantify, a population-based study, respective contributions excess adiposity (body mass index [BMI]), waist circumference (WC), fasting insulin levels, and sensitivity variation resting blood pressure. Quebec Health Survey used obtain plasma glucose levels pressure as well anthropometric measurements representative sample 907 men 937 women. When divided into...
<b>Background:</b> Screening for increased waist circumference and hypertriglyceridemia (the hypertriglyceridemic-waist phenotype) has been proposed as an inexpensive approach to identify patients with excess intra-abdominal adiposity associated metabolic abnormalities. We examined the relationship between phenotype risk of coronary artery disease in apparently healthy individuals. <b>Methods:</b> A total 21 787 participants aged 45–79 years were followed a mean 9.8 (standard deviation 1.7)...
This study examined the relationships of two inflammatory cytokines, IL-6 and TNF-alpha, to visceral adiposity indices plasma glucose-insulin homeostasis.Plasma levels TNF-alpha were measured in 189 untreated asymptomatic men (aged 43.7 +/- 7.8 yr; body mass index 29.0 4.3 kg/m(2); waist girth 98.6 10.3 cm).Significant positive associations found between both cytokines with adipose tissue distribution (0.15 < or = r 0.32; P 0.05) as well homeostasis variables (0.22 0.28; <0.05). Comparison...