A5002415824- Foot and Ankle Surgery
- Tendon Structure and Treatment
- Sports injuries and prevention
- Orthopedic Surgery and Rehabilitation
- Peripheral Nerve Disorders
- Knee injuries and reconstruction techniques
- Lower Extremity Biomechanics and Pathologies
- Adipokines, Inflammation, and Metabolic Diseases
- Muscle activation and electromyography studies
- Shoulder Injury and Treatment
- Dermatology and Skin Diseases
- Food Allergy and Anaphylaxis Research
- Ion Channels and Receptors
- Tracheal and airway disorders
- Respiratory viral infections research
University of Rochester
2025
Huashan Hospital
2022-2024
Fudan University
2022-2024
State Key Laboratory of Medical Neurobiology
2024
Shanghai Stomatological Hospital
2024
Human respiratory syncytial virus (HRSV) coinfection with other pathogens frequently occurs in young children acute illness. However, the epidemiological patterns and associated disease burden of HRSV coinfections pediatric populations remain poorly characterized. Analysis hospitalized under 5 years Zhejiang Province from 2018 to 2023 revealed that 20.4% experienced coinfections, bacterial substantially exceeding viral (14.1% vs. 5.3%). M. pneumoniae S. emerged as predominant copathogens,...
Abstract Purpose The aim of this study was to compare the clinical outcomes between patients with chronic ankle instability (CAI) undergoing arthroscopic anterior talofibular ligament (ATFL) repair who received elastic bandage treatment and those lower-leg cast immobilization. Methods CAI isolated ATFL injury from January 2017 August 2019 were included in study. visual analogue scale (VAS) at rest during activities, American Orthopedic Foot Ankle Society (AOFAS) score, Karlsson Functional...
Arthroscopic anterior talofibular ligament repair (AATFLR) is a surgical strategy to treat chronic ankle instability (CAI) patients. This study identified risk factors that influenced the functional outcomes of AATFLR for CAI and developed prognostic nomogram predicting in future cases.
Lateral ankle sprains (LAS) might lead to joint sensory deafferentation, which induces maladaptive neuroplasticity, especially the morphological atrophy of cerebellar vermis. However, longitudinal evidence on causality injury and neural differences is still lacking. To this end, study aimed determine whether morphology central nervous system would be altered before after ligament transection in LAS mouse models. A total 40 C57BL/6 mice were randomly divided among LAS, Sham Blank groups. We...
Ankle-foot sprains are the most common musculoskeletal injuries, which can impair balance and theoretically increase risk of falls, but still, there is a lack evidence supporting direct association between ankle-foot future falls. UK Biobank cohort was utilized to measure fall with covariates adjusted. Then, two-sample Mendelian randomization (MR) analysis applied based on genetically predicated from FinnGen validate causal relationship. Finally, cerebellar neuroimaging features were used...
Lateral ankle sprains (LAS) are associated with corticospinal pathway deficits. Existing evidence is primarily based on cross-sectional investigations and noncausal speculations. This study aims to determine whether maladaptive alterations occur pre- postligament transection in LAS mouse models. Additionally, this explores the more pronounced adolescent mice than adults. Twenty-four 8-week-old twenty-four 24-week-old adult were randomly assigned lateral ligament or sham surgery....
Background: Previous studies have revealed that early postoperative rehabilitation of chronic lateral ankle instability is just as crucial surgical intervention. Immediate weightbearing has yielded good clinical results; however, randomized controlled been limited. Purpose: To compare the outcomes patients with immediate after ligament repair those delayed 2 weeks in a prospective study. Study Design: Randomized trial; Level evidence, 1. Methods: Patients who underwent arthroscopic anterior...
The prevalent itching condition associated with aging, historically referred to as senile pruritus, diminishes quality of life. Despite its impact, effective treatments remain elusive, largely due an incomplete understanding pathological cause. In this study, we reveal a subset dorsal root ganglion neurons enriched Zn 2+ that express the vesicular transporter TMEM163. These form direct synapses and modulate activity spinal NPY + inhibitory interneurons. aged mice, both expression TMEM163...