A5101821173- Advanced biosensing and bioanalysis techniques
- Biosensors and Analytical Detection
- Liver Disease Diagnosis and Treatment
- Liver Disease and Transplantation
- Head and Neck Cancer Studies
- Cancer-related molecular mechanisms research
- RNA Interference and Gene Delivery
- Cancer Genomics and Diagnostics
- Metastasis and carcinoma case studies
- Bacteriophages and microbial interactions
- Medicinal Plants and Bioactive Compounds
- Head and Neck Surgical Oncology
- Intracerebral and Subarachnoid Hemorrhage Research
- Acute Ischemic Stroke Management
- Cancer Immunotherapy and Biomarkers
- Cerebrovascular and Carotid Artery Diseases
- Hepatitis Viruses Studies and Epidemiology
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- SARS-CoV-2 detection and testing
- HIV Research and Treatment
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Phytochemistry and Biological Activities
- RNA modifications and cancer
- Hepatitis C virus research
Zhejiang University
2025
Nanjing Medical University
2019-2025
Jiangsu Province Hospital
2025
The Affiliated Yongchuan Hospital of Chongqing Medical University
2013-2024
Chongqing Medical University
2013-2024
University of Technology Sydney
2024
Fudan University
2019-2024
Hunan University of Technology
2022-2023
Xijing Hospital
2015-2022
Southern Medical University
2018-2022
Health professions preventing and controlling Coronavirus Disease 2019 are prone to skin mucous membrane injury, which may cause acute chronic dermatitis, secondary infection aggravation of underlying diseases. This is a consensus Chinese experts on protective measures advice hand-cleaning- medical-glove-related hand protection, mask- goggles-related face UV-related eye nasal oral mucosa outer ear, hair protection. It necessary strictly follow standards wearing equipment specification...
Abstract Telomerase is now considered to be a valuable biomarker and therapeutic target in the diagnosis treatment of cancerous diseases, which brings an urgent need development fast efficient telomerase detection strategies. Here, new surface enhanced Raman scattering (SERS) based protocol using telomeric elongation controlled SERS (TEC‐SERS) effect for ultrasensitive presented. The TEC‐SERS not only provides unprecedented high sensitivity but also avoids laborious PCR procedures. limit...
As detection signal, UCNP fluorescence could improve the ability of biosensor in complex biological samples. UCNPs unbound to bacteria be separated by magnet, improving sensitivity and time biosensor.
This study aims to explore the regulatory role of cuproptosis in carotid intimal hyperplasia (IH), providing new insights into its pathophysiological mechanisms and potential diagnostic therapeutic strategies. Methods: We downloaded single-cell sequencing bulk transcriptome data from GEO database screen for copper-growth-associated genes (CAGs) using machine-learning algorithms, including Random Forest Support Vector Machine. After identifying relevant genes, we verified CAGs expression IH...
This study aims to evaluate the clinical effectiveness of trilaciclib in preventing myelosuppression patients with esophageal cancer undergoing chemotherapy. Based on use trilaciclib, 81 were divided into a primary prevention group (PP group, n = 49) and secondary (SP 32). The incidence myelosuppression, antibiotic usage rate, survival outcomes, other treatment-related toxicities analyzed using chi-square tests Kaplan–Meier curves. chemotherapy-induced SP was significantly higher than that...
Abstract Background Treatment guidelines for a variety of cancers have been increasingly used in clinical practice, and resulted major improvement patient outcomes. However, recommended regimens (even first‐line treatments) are clearly not ideal every patients. In the present study, we mini patient‐derived xenograft (mini‐PDX) next‐generation sequencing to develop personalized treatment with metastatic duodenal adenocarcinoma. Methods Resected metachronous tumor tissues were implanted into...
Gastric cancer is a frequent malignant tumor worldwide and its early detection crucial for curing the disease enhancing patients' survival rate. This study aimed to assess whether multi-disciplinary team (MDT) can improve rate of gastric (EGC).The EGC at Digestive Endoscopy Center, Affiliated Hospital, Zunyi Medical College, China between September 2013 2015 was analyzed. MDT diagnosis in hospital established 2014. The divided into 2 time periods: 1, August 31, 2014 (period 1) 2).A total...
Bile acids (BAs) play a crucial role in the human body's defense against infections caused by bacteria, fungi, and viruses. BAs counteract not only through interactions with intestinal bacteria exhibiting bile salt hydrolases (BSHs) activity but also directly combat infections. Building upon our research group's previous discoveries highlighting of combating infections, we have initiated an in-depth investigation into between microbiota. Leveraging existing literature,...
Objectives: China has entered the aging society, but social support systems for elderly are underdeveloped, which may make feel anxiety about their health and life quality. Given prevalence of generalized disorder (GAD) in elderly, it is very important to pay more attention treatment old adults. Although cognitive behavioral therapy targeting intolerance uncertainty (CBT-IU) been applied different groups patients with GAD, few studies have performed date. In addition, effects CBT-IU not well...
The antiaging effect of Inula britannica flower total flavonoids (IBFTF) on aging mice induced by D‐galactose and its mechanism was examined in this study. From the results, biochemical indexes histological analysis skin tissues showed that IBFTF could effectively improve antioxidant enzyme activity mice, enhance activities superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GSH‐Px) tissue, decrease malondialdehyde (MDA) content. Besides, maintain collagen, hydroxyproline...
Multifunctional nano-materials that can be used to monitor the expression of specific biomarkers and serve as vehicles for controlled drug delivery are highly desirable. Herein, we report a new DNA-hybrid-gated core-shell upconversion nanoprobe (UCNP@MOF/DOX) fluorescence analysis microRNA-21 (miR-21), which also triggers release loaded in probes on-demand anti-cancer treatment. The is built on merits ultraviolet-visible light nanoparticles (UCNPs) excited by near-infrared (NIR)...
Abstract An efficient, safe, and viable process has been developed for large-scale preparation of salidroside, a natural product. The consists two chemical steps, which produce the salidroside on multikilogram scale with 72% overall yield >98% purity. A series novel analogs were prepared according to same method.
Abstract Background IGF‐binding protein 3（IGFBP‐3）has previously been identified as tumor marker. The present study aimed to investigate the clinical significance of serum IGFBP‐3 in colorectal cancer (CRC). Methods Serum was collected from 70 CRC patients and 50 healthy volunteer controls. carcinoembryonic antigen (CEA) levels were measured using electrogenerated chemiluminescence immunoassay compared between groups. Relationships level characteristics also analyzed. A receiver operator...
In December 2019, a severe acute respiratory syndrome caused by SARS-CoV-2 spread rapidly worldwide. Portable nucleic acid tests of are critically important for diagnostics. this study, we used an isothermal amplification method—Multienzyme Isothermal Rapid Amplification (MIRA)—for rapid detection SARS-CoV-2. We designed the primers and probes in ORF1ab N gene The amplicons could be monitored lateral flow dipsticks (LFDs). reaction temperature, time, concentrations probes, working volume...