A5066266709- Plant-Microbe Interactions and Immunity
- Plant Molecular Biology Research
- Plant Reproductive Biology
- Plant Pathogens and Resistance
- Plant Virus Research Studies
- Plant Pathogens and Fungal Diseases
- Plant Pathogenic Bacteria Studies
- Fungal Plant Pathogen Control
- Plant Stress Responses and Tolerance
- Mycotoxins in Agriculture and Food
- Plant tissue culture and regeneration
- Plant Parasitism and Resistance
- Legume Nitrogen Fixing Symbiosis
- Plant Disease Resistance and Genetics
- Antimicrobial Peptides and Activities
- Monoclonal and Polyclonal Antibodies Research
- Phytoplasmas and Hemiptera pathogens
- Toxin Mechanisms and Immunotoxins
- Vaccine Coverage and Hesitancy
- Genomics and Phylogenetic Studies
- SARS-CoV-2 and COVID-19 Research
- RNA and protein synthesis mechanisms
- Transgenic Plants and Applications
- COVID-19 diagnosis using AI
- Polysaccharides and Plant Cell Walls
Nanjing Agricultural University
2021-2025
China Agricultural University
2012-2025
Max Planck Institute for Plant Breeding Research
2017-2023
Affiliated Hospital of Guizhou Medical University
2020-2023
Guiyang Medical University
2020-2023
University of Pennsylvania
2017-2023
University of Cologne
2017-2022
Tsinghua University
2013-2022
Center for Life Sciences
2015-2022
Philadelphia University
2021
Tetrameric immune receptors Nucleotide-binding/leucine-rich repeat (NLR) detect pathogen effectors and trigger a plant's response. Two groups have now defined the structures of two NLRs that carry Toll-like interleukin-1 receptor (TIR) domains (TIR-NLRs) (see Perspective by Tian Li). Ma et al. studied Arabidopsis thaliana TIR-NLR RPP1 (recognition Peronospora parasitica 1) its response to from an oomycete pathogen. Martin Nicotiana benthamiana ROQ1 XopQ Xanthomonas effector. Both found these...
Plant nucleotide-binding leucine-rich repeat-containing (NLR) receptors with an N-terminal Toll/interleukin-1 receptor (TIR) domain sense pathogen effectors to enable TIR-encoded nicotinamide adenine dinucleotide hydrolase (NADase) activity for immune signaling. TIR-NLR signaling requires the helper NLRs N requirement gene 1 (NRG1), Activated Disease Resistance (ADR1), and Enhanced Susceptibility (EDS1), which forms a heterodimer each of its paralogs Phytoalexin Deficient 4 (PAD4)...
Plant pathogen-activated immune signaling by nucleotide-binding leucine-rich repeat (NLR) receptors with an N-terminal Toll/interleukin-1 receptor (TIR) domain converges on Enhanced Disease Susceptibility 1 (EDS1) and its direct partners, Phytoalexin Deficient 4 (PAD4) or Senescence-Associated Gene 101 (SAG101). TIR-encoded nicotinamide adenine dinucleotide hydrolase (NADase) produces molecules to promote exclusive EDS1-PAD4 EDS1-SAG101 interactions helper NLR subclasses. In this work, we...
Abstract Plant nucleotide-binding leucine-rich repeat (NLR) immune receptors with an N-terminal Toll/interleukin-1 receptor (TIR) domain mediate recognition of strain-specific pathogen effectors, typically via their C-terminal ligand-sensing domains 1 . Effector binding enables TIR-encoded enzymatic activities that are required for TIR–NLR (TNL)-mediated immunity 2,3 Many truncated TNL proteins lack effector-sensing but retain similar and 4,5 The mechanism underlying the activation these TIR...
Quantitative studies using validated questionnaires on post-traumatic stress disorder (PTSD) of Nurses exposed to corona virus disease 2019 (COVID-19) in China are rare and the baseline PTSD must first be evaluated before prevention. This study aimed investigate factors potentially involved level COVID-19 China.In this cross-sectional study, male female (n = 202) from HuBei were included final sample. The Checklist-Civilian (PCL-C) questionnaire Simplified Coping Style Questionnaire (SCSQ)...
How specificity is conferred within gene regulatory networks an important problem in biology. The basic helix-loop-helix PHYTOCHROME-INTERACTING FACTORs (PIFs) and single zinc-finger CYCLING DOF (CDFs) mediate growth responses of Arabidopsis to light temperature. We show that these two classes transcription factor (TF) act cooperatively. CDF2 PIF4 are temporally spatially co-expressed, they interact form a protein complex the same genetic pathway promote hypocotyl cell elongation....
Fusarium head blight (FHB), caused by the graminearum species complex, is a devastating fungal disease resulting in substantial yield and quality losses. Ergosterol biosynthesis inhibitors (EBIs) are most popular chemicals for controlling FHB. Recently, resistance of F. to EBIs has emerged field, an amino acid substitution (G443S) sterol 14α-demethylase FgCYP51A was detected field resistant strains. To further illustrate mechanism EBIs, site-directed mutants conferring G443S were generated...
To evaluate the clinical and computed tomographic (CT) features in patients with COVID-19 pneumonia confirmed by real-time reverse transcriptase polymerase chain reaction (rRT-PCR) amplification of viral DNA from a sputum sample.
In a survey and three experiments (one preregistered with nationally representative sample), we examined if vaccination requirements are likely to backfire, as commonly feared. We investigated relative encouraging free choice in vaccination, requiring vaccine weakens or strengthens intentions, both general among individuals predisposition experience psychological reactance. the four studies, compared choice, strengthened intentions across racial ethnic groups, levels of trait The results...
Abstract Gametophyte development in angiosperms occurs within diploid sporophytic structures and requires coordinated development; e.g., of the male gametophyte pollen depends on surrounding tissue, tapetum. The mechanisms underlying this interaction remain poorly characterized. peptide CLAVATA3/EMBRYO SURROUNDING REGION-RELATED 19 (CLE19) plays a “braking” role preventing harmful overexpression tapetum transcriptional regulators to ensure normal Arabidopsis . However, CLE19 receptor is...
Inhibiting pathogen chemotaxis is a promising strategy for reducing disease pressure. However, this currently in the proof-of-concept stage. Here, Phytophthora sojae was used as model, its biflagellated zoospores could sense genistein, soybean root exudate, to navigate host and initiate infection. We identify P. IRK1 (isoflavone-insensitive receptor kinase 1) with PsIRK2 functioning coreceptor that enhances binding affinity of PsIRK1 genistein regulates by phosphorylating G protein α...
Phytophthora cactorum is a devastating pathogen that infects wide range of plants and causes rot disease, which has resulted in great economic losses crop production. Therefore, the rapid practicable detection P. important for disease monitoring forecasting. In this study, we developed lateral flow recombinase polymerase amplification (LF-RPA) assay sensitive visual cactorum. Specific primers were designed based on ras-related protein gene Ypt1; all 10 isolates yielded positive results,...
Abstract Plant nucleotide-binding leucine-rich-repeat receptors (NLRs) with an N-terminal toll/interleukin-1 receptor (TIR) domain sense pathogen effectors to enable TIR-encoded NADase activity for immune signaling. TIR-NLR (TNL) signaling requires conserved helper NLRs NRG1 and ADR1 the lipase-like protein EDS1 that functions as a heterodimer each of its paralogs PAD4 SAG101. We show TIR-containing proteins catalyze production 2’-(5’’-phosphoribosyl)-5’-adenosine mono-/di-phosphate...