A5100625307- RNA modifications and cancer
- Polyamine Metabolism and Applications
- S100 Proteins and Annexins
- Cancer-related Molecular Pathways
- RNA Research and Splicing
- NF-κB Signaling Pathways
- Liver Disease Diagnosis and Treatment
- Metabolism and Genetic Disorders
- Cancer, Lipids, and Metabolism
- Antibiotics Pharmacokinetics and Efficacy
- Biochemical effects in animals
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- MicroRNA in disease regulation
- Neurogenesis and neuroplasticity mechanisms
- Epigenetics and DNA Methylation
- Cancer-related gene regulation
- Cancer Research and Treatments
- Flavonoids in Medical Research
- Drug Transport and Resistance Mechanisms
- Protease and Inhibitor Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Electron Spin Resonance Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- interferon and immune responses
- Circular RNAs in diseases
China Agricultural University
2025
Hebei Medical University
2024
Second Hospital of Hebei Medical University
2024
Air Force Medical University
2004-2023
Fuyang Second People's Hospital
2023
Anhui Medical University
2023
Shanxi Provincial Cancer Hospital
2021
Gansu Provincial Hospital
2020
China-Japan Friendship Hospital
2019
Guangdong Provincial Center for Disease Control and Prevention
2018
Peripheral T cell lymphopenia is a clinical phenomenon in some patients with dermatomyositis (DM). Patients are more susceptible to life-threatening infections. However, the pathogenesis of remains unclear. In this study, we aimed determine retinoic acid-inducible gene I (RIG-I) expression peripheral lymphocytes and explore correlation between RIG-I DM. The mRNA protein levels were determined 26 treatment-naive DM by q-PCR Western blot. apoptosis was detected flow cytometry. associations...
The objective was to investigate the anti-inflammatory effects of salidroside through PI3K/Akt signaling pathway and its protective on acute hypoxia-induced myocardial injury in rats.
5-Azacytidine is a well-known anticancer drug that clinically used in the treatment of breast cancer, melanoma and colon cancer. It has been reported 5-azacytidine suppresses biological behavior esophageal cancer cells. However, corresponding mechanisms remain unclear. In this study, using Transwell invasion cell proliferation assays, we demonstrated significantly inhibited metastasis EC9706 cells, upregulated expression cadherin 1 (CDH1) SRY-box containing gene 17 (SOX17). Moreover,...
Ciprofol is a novel short-acting intravenous anaesthetic developed in China that mainly metabolized by cytochrome P450 2B6 (CYP2B6) and uridine diphosphate glucuronosyltransferase 1A9 (UGT1A9). Currently, insufficient evidence available to support drug‒drug interactions between ciprofol CYP2B6 inactivators. Here, we established high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method assess the concentration of investigated effects psoralen clopidogrel on...
To investigate the effects of exposure to an 1800 MHz electromagnetic field on cell death and proliferation in developing brain, postnatal day 7 (P7) P21 healthy Kunming mice were randomly assigned into experimental control groups. The groups exposed for 8 h daily three consecutive days. thymidine analog 5-bromo-2-deoxyuridine (BrdU) was injected intraperitoneally 1 before each session, all animals sacrificed 24 after last exposure. Cell markers detected by immunohistochemistry dentate gyrus...
Circular RNAs (circRNAs) are reported as competing endogenous (ceRNAs) and play key roles in non-small-cell lung cancer (NSCLC) progression. Thus, this study was aimed at clarifying underlying molecular mechanisms of circHUWE1 NSCLC.The quantitative real-time polymerase chain reaction (RT-qPCR) western blot analyses were used for examining circHUWE1, microRNA-34a-5p (miR-34a-5p), tumor necrosis factor alpha-induced protein 8 (TNFAIP8). IC50 cisplatin (DDP) A549/DDP H1299/DDP cells cell...
Abstract Phosgene, a highly dangerous chemical warfare agent, is widely used as an industrial chemical. Phosgene inhalation causes acute lung injury (ALI), which may further progress into pulmonary edema. Currently, there no known antidote for phosgene poisoning. Alpha-1 antitrypsin (α1-AT) protease inhibitor that has been to treat emphysema patients, who are deficient in α1-AT, decades. Recent studies have shown α1-AT both anti-inflammatory and anti-SARS-CoV-2 effects. In this study, we...